Effect of respiratory motion on free‐breathing 3D stack‐of‐radial liver relaxometry and improved quantification accuracy using self‐gating

2019 ◽  
Vol 83 (6) ◽  
pp. 1964-1978 ◽  
Author(s):  
Xiaodong Zhong ◽  
Tess Armstrong ◽  
Marcel D. Nickel ◽  
Stephan A.R. Kannengiesser ◽  
Li Pan ◽  
...  
Keyword(s):  
Respiratory Motion ◽  
Free Breathing ◽  
Quantification Accuracy

scholarly journals Correcting versus resolving respiratory motion in free-breathing whole-heart MRA: a comparison in patients with thoracic aortic disease

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Robert E. Stroud ◽  
Davide Piccini ◽  
U. Joseph Schoepf ◽  
John Heerfordt ◽  
Jérôme Yerly ◽  
...  
Keyword(s):  
Respiratory Motion ◽  
Free Breathing ◽  
Aortic Disease ◽  
Thoracic Aortic Disease ◽  
Whole Heart

scholarly journals Assessing and accounting for the impact of respiratory motion on FDG uptake and viable volume for liver lesions in free-breathing PET using respiration-suspended PET images as reference

2014 ◽  
Vol 41 (9) ◽  
pp. 091905 ◽  
Author(s):  
Guang Li ◽  
C. Ross Schmidtlein ◽  
Irene A. Burger ◽  
Carole A. Ridge ◽  
Stephen B. Solomon ◽  
...  
Keyword(s):  
Respiratory Motion ◽  
Free Breathing ◽  
Liver Lesions ◽  
Fdg Uptake ◽  
The Impact

scholarly journals Respiratory Motion-Registered Isotropic Whole-Heart T2 Mapping in Patients With Acute Non-ischemic Myocardial Injury

2021 ◽  
Vol 8 ◽  
Author(s):  
Karolina Dorniak ◽  
Lorenzo Di Sopra ◽  
Agnieszka Sabisz ◽  
Anna Glinska ◽  
Christopher W. Roy ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Respiratory Motion ◽  
Myocardial Injury ◽  
T2 Mapping ◽  
Myocardial Edema ◽  
Free Breathing ◽  
Myocardial Inflammation ◽  
Patient Cohort ◽  
Significant Difference ◽  
Whole Heart

Background: T2 mapping is a magnetic resonance imaging technique that can be used to detect myocardial edema and inflammation. However, the focal nature of myocardial inflammation may render conventional 2D approaches suboptimal and make whole-heart isotropic 3D mapping desirable. While self-navigated 3D radial T2 mapping has been demonstrated to work well at a magnetic field strength of 3T, it results in too noisy maps at 1.5T. We therefore implemented a novel respiratory motion-resolved compressed-sensing reconstruction in order to improve the 3D T2 mapping precision and accuracy at 1.5T, and tested this in a heterogeneous patient cohort.Materials and Methods: Nine healthy volunteers and 25 consecutive patients with suspected acute non-ischemic myocardial injury (sarcoidosis, n = 19; systemic sclerosis, n = 2; acute graft rejection, n = 2, and myocarditis, n = 2) were included. The free-breathing T2 maps were acquired as three ECG-triggered T2-prepared 3D radial volumes. A respiratory motion-resolved reconstruction was followed by image registration of the respiratory states and pixel-wise T2 mapping. The resulting 3D maps were compared to routine 2D T2 maps. The T2 values of segments with and without late gadolinium enhancement (LGE) were compared in patients.Results: In the healthy volunteers, the myocardial T2 values obtained with the 2D and 3D techniques were similar (45.8 ± 1.8 vs. 46.8 ± 2.9 ms, respectively; P = 0.33). Conversely, in patients, T2 values did differ between 2D (46.7 ± 3.6 ms) and 3D techniques (50.1 ± 4.2 ms, P = 0.004). Moreover, with the 2D technique, T2 values of the LGE-positive segments were similar to those of the LGE-negative segments (T2LGE−= 46.2 ± 3.7 vs. T2LGE+ = 47.6 ± 4.1 ms; P = 0.49), whereas the 3D technique did show a significant difference (T2LGE− = 49.3 ± 6.7 vs. T2LGE+ = 52.6 ± 8.7 ms, P = 0.006).Conclusion: Respiratory motion-registered 3D radial imaging at 1.5T led to accurate isotropic 3D whole-heart T2 maps, both in the healthy volunteers and in a small patient cohort with suspected non-ischemic myocardial injury. Significantly higher T2 values were found in patients as compared to controls in 3D but not in 2D, suggestive of the technique's potential to increase the sensitivity of CMR at earlier stages of disease. Further study will be needed to demonstrate its accuracy.

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