scholarly journals Non-contrast myocardial infarct scar assessment using a hybrid native T1 and magnetization transfer imaging sequence at 1.5T

2018 ◽  
Vol 81 (5) ◽  
pp. 3192-3201 ◽  
Author(s):  
Chong Duan ◽  
Yanjie Zhu ◽  
Jihye Jang ◽  
Jennifer Rodriguez ◽  
Ulf Neisius ◽  
...  
Biosensors ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 302
Author(s):  
Baolan Lu ◽  
Jinjiang Lin ◽  
Jinfang Du ◽  
Shaofu He ◽  
Qinghua Cao ◽  
...  

In this study, we investigated the utility of native T1 mapping in differentiating between various grades of fibrosis and compared its diagnostic accuracy to magnetization transfer imaging (MTI) in a rat model of CD. Bowel specimens (64) from 46 CD model rats undergoing native T1 mapping and MTI were enrolled. The longitudinal relaxation time (T1 value) and normalized magnetization transfer ratio (MTR) were compared between none-to-mild and moderate-to-severe fibrotic bowel walls confirmed by pathological assessments. The results showed that the correlation between the T1 value and fibrosis (r = 0.438, p < 0.001) was lower than that between the normalized MTR and fibrosis (r = 0.623, p < 0.001). Overall, the T1 values (t = −3.066, p = 0.004) and normalized MTRs (z = 0.081, p < 0.001) in none-to-mild fibrotic bowel walls were lower than those in moderate-to-severe fibrotic bowel walls. The area under the curve (AUC) of the T1 value (AUC = 0.716, p = 0.004) was significantly lower than that of the normalized MTR (AUC = 0.881, p < 0.001) in differentiating moderate-to-severe fibrosis from none-to-mild fibrosis (z = −2.037, p = 0.042). Our results support the view that the T1 value could be a promising imaging biomarker in grading the fibrosis severity of CD. However, the diagnostic performance of native T1 mapping was not superior to MTI.


2007 ◽  
Vol 28 (10) ◽  
pp. 1938-1942 ◽  
Author(s):  
A.C.G.M. van Es ◽  
W.M. van der Flier ◽  
F. Admiraal Behloul ◽  
H. Olofsen ◽  
E.L.E.M. Bollen ◽  
...  

2004 ◽  
Vol 137 (6) ◽  
pp. 1172
Author(s):  
S.J. Hickman ◽  
A.T. Toosy ◽  
S.J. Jones ◽  
D.R. Altmann ◽  
K.A. Miszkiel ◽  
...  

Author(s):  
Avinash Kali ◽  
Ivan Cokic ◽  
Hsin-Jung Yang ◽  
Behzad Sharif ◽  
Rohan Dharmakumar

2020 ◽  
Vol 68 ◽  
pp. 66-74 ◽  
Author(s):  
Matthew J. Cronin ◽  
Junzhong Xu ◽  
Francesca Bagnato ◽  
Daniel F. Gochberg ◽  
John C. Gore ◽  
...  

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