scholarly journals Non‐contrast enhanced simultaneous 3D whole‐heart bright‐blood pulmonary veins visualization and black‐blood quantification of atrial wall thickness

2018 ◽  
Vol 81 (2) ◽  
pp. 1066-1079 ◽  
Author(s):  
Giulia Ginami ◽  
Karina Lòpez ◽  
Rahul K. Mukherjee ◽  
Radhouene Neji ◽  
Camila Munoz ◽  
...  
Keyword(s):  
Wall Thickness ◽  
Pulmonary Veins ◽  
Black Blood ◽  
Atrial Wall ◽  
Contrast Enhanced ◽  
Whole Heart ◽  
Bright Blood

scholarly journals Accelerated high-resolution free-breathing 3D whole-heart T2-prepared black-blood and bright-blood cardiovascular magnetic resonance

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Teresa Correia ◽  
Giulia Ginami ◽  
Imran Rashid ◽  
Giovanna Nordio ◽  
Reza Hajhosseiny ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Healthy Subjects ◽  
Free Breathing ◽  
Black Blood ◽  
Contrast Injection ◽  
Post Contrast ◽  
Whole Heart ◽  
Bright Blood

Abstract Background The free-breathing 3D whole-heart T2-prepared Bright-blood and black-blOOd phase SensiTive inversion recovery (BOOST) cardiovascular magnetic resonance (CMR) sequence was recently proposed for simultaneous bright-blood coronary CMR angiography and black-blood late gadolinium enhancement (LGE) imaging. This sequence enables simultaneous visualization of cardiac anatomy, coronary arteries and fibrosis. However, high-resolution (< 1.4 × 1.4 × 1.4 mm3) fully-sampled BOOST requires long acquisition times of ~ 20 min. Methods In this work, we propose to extend a highly efficient respiratory-resolved motion-corrected reconstruction framework (XD-ORCCA) to T2-prepared BOOST to enable high-resolution 3D whole-heart coronary CMR angiography and black-blood LGE in a clinically feasible scan time. Twelve healthy subjects were imaged without contrast injection (pre-contrast BOOST) and 10 patients with suspected cardiovascular disease were imaged after contrast injection (post-contrast BOOST). A quantitative analysis software was used to compare accelerated pre-contrast BOOST against the fully-sampled counterpart (vessel sharpness and length of the left and right coronary arteries). Moreover, three cardiologists performed diagnostic image quality scoring for clinical 2D LGE and both bright- and black-blood 3D BOOST imaging using a 4-point scale (1–4, non-diagnostic–fully diagnostic). A two one-sided test of equivalence (TOST) was performed to compare the pre-contrast BOOST images. Nonparametric TOST was performed to compare post-contrast BOOST image quality scores. Results The proposed method produces images from 3.8 × accelerated non-contrast-enhanced BOOST acquisitions with comparable vessel length and sharpness to those obtained from fully- sampled scans in healthy subjects. Moreover, in terms of visual grading, the 3D BOOST LGE datasets (median 4) and the clinical 2D counterpart (median 3.5) were found to be statistically equivalent (p < 0.05). In addition, bright-blood BOOST images allowed for visualization of the proximal and middle left anterior descending and right coronary sections with high diagnostic quality (mean score > 3.5). Conclusions The proposed framework provides high‐resolution 3D whole-heart BOOST images from a single free-breathing acquisition in ~ 7 min.

scholarly journals 3D high-resolution atrial wall thickness maps using black-blood PSIR

2015 ◽  
Vol 17 (S1) ◽  
Author(s):  
Marta Varela ◽  
Christoph Kolbitsch ◽  
Adeline Theron ◽  
Ross Morgan ◽  
Markus Henningsson ◽  
...  
Keyword(s):  
High Resolution ◽  
Wall Thickness ◽  
Black Blood ◽  
Atrial Wall

scholarly journals Simultaneous 3D whole‐heart bright‐blood and black blood imaging for cardiovascular anatomy and wall assessment with interleaved T 2 prep‐IR

2019 ◽  
Vol 82 (1) ◽  
pp. 312-325 ◽  
Author(s):  
Giorgia Milotta ◽  
Giulia Ginami ◽  
Gastao Cruz ◽  
Radhouene Neji ◽  
Claudia Prieto ◽  
...  
Keyword(s):  
Black Blood ◽  
Black Blood Imaging ◽  
Whole Heart ◽  
Blood Imaging ◽  
Bright Blood

scholarly journals Personalized atrial fibrillation ablation by tailoring ablation index to the left atrial wall thickness. the ablate by-law single center study

EP Europace ◽  
2021 ◽  
Vol 23 (Supplement_3) ◽  
Author(s):  
C Teres ◽  
D Penela ◽  
D Soto-Iglesias ◽  
B Jauregui ◽  
A Ordonez ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Wall Thickness ◽  
Left Atrial ◽  
Pulmonary Veins ◽  
Procedure Time ◽  
Atrial Wall ◽  
Af Ablation ◽  
Left Atrial Wall ◽  
Ablation Index ◽  
First Pass

Abstract Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): Dr Teres is funded by the research fellowship grant from the Swiss Heart Rhythm Foundation, Dr Carreno was funded was funded by a Scholarship from Sociedad Española de Cardiología (SEC). Introduction Left atrial wall thickness (LAWT) is a determinant of transmural lesion formation during atrial fibrillation (AF) ablation. The utility of ablation index (AI) to dose radiofrequency (RF) delivery for the reduction of AF recurrences has already been proven with a target AI ≥ 400 at the posterior wall and ≥550 at the anterior wall. Objective To determine if adapting AI to atrial wall thickness (AWT) is feasible, effective and safe during AF ablation. Methods Consecutive patients referred for a first PAF ablation. LAWT 3D-maps were obtained from multidetector computed tomography (MDCT) and integrated into the CARTO navigation system. LAWT maps were semi-automatically computed from the MDCT as the local distance between the LA endo and epicardium and categorized into 1mm-layers and AI was titrated to the LAWT, as follows: Thickness &lt; 1 mm (red): 300; 1-2 mm (yellow): 350; 2-3 mm (green): 400; 3-4 mm (blue): 450; &gt; 4 mm (purple): 450 (Figure). The ablation line was designed in a personalized fashion to avoid thicker regions. All ablation procedures were performed under general anesthesia with a high frequency low-volume ventilation. Primary endpoints were acute efficacy and safety, and freedom from AF recurrences. Follow-up (FU) was scheduled at 1, 3, 6, and every 6 months thereafter. Results 90 patients [60 (67 %) male, age 58 ± 13 years] were included. Mean LAWT was 1.25 ± 0.62 mm. Mean AI was 366 ± 26 on the right pulmonary veins (RPVs) with a first-pass isolation in 84 (93%) patients and 380 ± 42 on the left pulmonary veins (LPVs) with first-pass in 87 (97%). Procedure time was 59 min [49-66]; RF time 14 min [12,5-16]; fluoroscopy time 0.7 min [0.5-1.4]. No major complication occurred. Eighty-six out of 90 (95.5%) patients were free of recurrence after a mean FU of 11 ± 4 months. Conclusions  Personalized AF ablation, adapting the AI to LAWT allowed decreasing RF delivery, fluoroscopy and procedure time while obtaining a high rate of first-pass isolation. Lesion durability as estimated by freedom from AF recurrences was as high as in more demanding ablation protocols. Abstract Figure. Personalized protocol and results

scholarly journals AB0474 CAROTID CONTRAST ENHANCED ULTRASOUND IN CASES OF TAKAYASU ARTERITIS COMPLICATED WITH BEHCET’S DISEASE

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1535.1-1535
Author(s):  
W. Fan ◽  
J. Zhu ◽  
P. Yu ◽  
L. Yu ◽  
X. Wang ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Clinical Data ◽  
Wall Thickness ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Contrast Enhanced Ultrasound ◽  
Artery Wall ◽  
Behcet's Disease ◽  
Contrast Enhanced ◽  
Carotid Wall

Background:Carotid contrast enhanced ultrasound (CEUS) is used for diagnosis and activity determination of patients with Takayasu’s arteritis (TA). However, very little is known about the carotid CEUS features of TA complicated with Behcet’s disease (BD).Objectives:This study reports the carotid CEUS features in cases of TA complicated with BD (TBD).Methods:A total of 10 carotid CEUS examinations were performed on 4 patients of TBD. 10 TA patients complicated with no rheumatoid disease were included as control group. For each carotid artery lesion, the carotid CEUS features was graded as follows: Grade 0, artery wall shows no microbubbles, Grade 1, artery wall shows limited or moderate microbubbles, Grade 2, artery wall shows severe microbubbles.Results:2/10 patients in TBD group has oral ulcer during the CEUS examination, while all the other patients included in our study showed no clinical symptoms related to active TA or BD. The carotid wall thickness was greater of CEUS grade 2 than grade 1 in both group(TBD: 2.62±0.74mm vs 1.66±0.22mm,p=0.001; TA:1.84±0.31mm vs 1.53±0.5mm,p=0.136). The carotid wall thickness was significantly greater in TBD group than TA group, but there was no significant differences between the two groups in clinical data and CEUS grade (table 1).Table 1.Clinical data and carotid CEUS features of both groupsTBDTApAge (year)32.5±3.4430.5±9.20.487Male320.605ESR (mm/h)4(2, 10)7(3.5, 11)0.406CRP (mg/L)6.42(0.55, 15.38)0.58(0.44, 5.05)0.168Wall thickness (mm)2.10±0.701.67±0.440.030CEUS grade 29120.527Conclusion:This study first shows carotid CEUS features in cases of TA complicated with BD, which may help with the comprehensive treatments of the disease.Disclosure of Interests: :None declared

scholarly journals Self-navigated 3D whole-heart MRA for non-enhanced surveillance of thoracic aortic dilation: a comparison to CTA

2021 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
P Poskaite ◽  
M Pamminger ◽  
C Kranewitter ◽  
C Kremser ◽  
M Reindl ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Aortic Aneurysm ◽  
Thoracic Aortic Aneurysm ◽  
Aortic Dilation ◽  
Subjective Image Quality ◽  
Contrast Enhanced ◽  
Whole Heart ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography

Abstract Funding Acknowledgements Type of funding sources: None. Background The natural history of thoracic aortic aneurysm (TAA) is one of progressive expansion. Asymptomatic patients who do not meet criteria for repair require conservative management including ongoing aneurysm surveillance, mostly carried out by contrast-enhanced computed tomography angiography (CTA). Purpose To prospectively compare image quality and reliability of a prototype non-contrast, self-navigated 3D whole-heart magnetic resonance angiography (MRA) with contrast-enhanced computed tomography angiography (CTA) for sizing of thoracic aortic aneurysm (TAA). Methods Self-navigated 3D whole-heart 1.5 T MRA was performed in 20 patients (aged 67 ± 8.6 years, 75% male) for sizing of TAA; a subgroup of 18 (90%) patients underwent additional contrast-enhanced CTA on the same day. Subjective image quality was scored according to a 4-point Likert scale and ratings between observers were compared by Cohen’s Kappa statistics. Continuous MRA and CTA measurements were analyzed with regression and Bland-Altman analysis. Results Overall subjective image quality as rated by two observers was 1 [interquartile range (IQR) 1-2] for self-navigated MRA and 1.5 [IQR 1-2] for CTA (p = 0.717). For MRA a perfect inter-observer agreement was found for presence of artefacts and subjective image sharpness (κ=1). Subjective signal inhomogeneity correlated highly with objectively quantified inhomogeneity of the blood pool signal (r = 0.78-0.824, all p &lt;0.0001). Maximum diameters of TAA as measured by self-navigated MRA and CTA showed excellent correlation (r = 0.997, p &lt; 0.0001) without significant inter-method bias (bias -0.0278, lower and upper limit of agreement -0.74 and 0.68, p = 0.749). Inter- and intraobserver correlation of aortic aneurysm as measured by MRA was excellent (r = 0.963 and 0.967, respectively) without significant bias (all p ≤ 0.05). Conclusion Self-navigated 3D whole-heart MRA enables reliable contrast- and radiation free aortic dilation surveillance without significant difference to standardized CTA while providing predictable acquisition time and by offering excellent image quality. Abstract Figure.

scholarly journals Aging Is Positively Associated with Peri-Sinus Lymphatic Space Volume: Assessment Using 3T Black-Blood MRI

2020 ◽  
Vol 9 (10) ◽  
pp. 3353
Author(s):  
Mina Park ◽  
Jin Woo Kim ◽  
Sung Jun Ahn ◽  
Yoon Jin Cha ◽  
Sang Hyun Suh
Keyword(s):  
Normal Subjects ◽  
The Elderly ◽  
Cancer Staging ◽  
Elderly Group ◽  
Black Blood ◽  
Intracranial Volume ◽  
Contrast Enhanced ◽  
Neurologically Normal ◽  
N 93 ◽  
Space Volume

Objectives: Aging is a major risk factor for many neurological disorders and is associated with dural lymphatic dysfunction. We sought to evaluate the association of aging with the volume of the peri-sinus lymphatic space using contrast-enhanced 3T T1-weighted black-blood magnetic resonance imaging (MRI). Methods: In this retrospective study, 165 presumed neurologically normal subjects underwent brain MRIs for cancer staging between April and November 2018. The parasagittal peri-sinus lymphatic space was evaluated using contrast-enhanced 3D T1-weighted black-blood MRIs, and volumes were measured with semiautomatic method. We compared the volumes of normalized peri-sinus lymphatic spaces between the elderly (≥65 years, n = 72) and non-elderly (n = 93) groups and performed multivariate logistic regression analyses to assess if aging is independently associated with the volume of normalized peri-sinus lymphatic spaces. Results: The normalized peri-sinus lymphatic space volume was significantly higher in the elderly than in the non-elderly (mean, 3323 ± 758.7 mL vs. 2968.7 ± 764.3 mL, p = 0.047). After adjusting the intracranial volume, age age was the strongest factor independently associated with peri-sinus lymphatic space volume (β coefficient, 28.4 (5.7–51.2), p = 0.015) followed by male sex (β coefficient, 672.4 (113.5–1230.8), p = 0.019). Conclusions: We found that the peri-sinus dural lymphatic space volume was higher in the elderly group than in the non-elderly group, and the increased peri-sinus lymphatic space was independently associated with aging. These findings indicate that the peri-sinus lymphatic space may be related with the aging process and lymphatic system dysfunction as well.

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