scholarly journals A generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol

2017 ◽  
Vol 79 (3) ◽  
pp. 1553-1558 ◽  
Author(s):  
Yin Wu ◽  
Iris Y. Zhou ◽  
Takahiro Igarashi ◽  
Dario L. Longo ◽  
Silvio Aime ◽  
...  
Keyword(s):  
Chemical Exchange ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer ◽  
Cest Mri

scholarly journals Renal pH Imaging Using Chemical Exchange Saturation Transfer (CEST) MRI: Basic Concept

2021 ◽  
pp. 241-256
Author(s):  
Dario Livio Longo ◽  
Pietro Irrera ◽  
Lorena Consolino ◽  
Phillip Zhe Sun ◽  
Michael T. McMahon
Keyword(s):  
Chemical Exchange ◽  
Kidney Diseases ◽  
Chemical Exchange Saturation Transfer ◽  
Functional Information ◽  
Saturation Transfer ◽  
Ph Changes ◽  
Ph Imaging ◽  
Cest Mri ◽  
Magnetic Resonance Imaging Mri ◽  
Renal Mri

AbstractMagnetic Resonance Imaging (MRI) has been actively explored in the last several decades for assessing renal function by providing several physiological information, including glomerular filtration rate, renal plasma flow, tissue oxygenation and water diffusion. Within MRI, the developing field of chemical exchange saturation transfer (CEST) has potential to provide further functional information for diagnosing kidney diseases. Both endogenous produced molecules as well as exogenously administered CEST agents have been exploited for providing functional information related to kidney diseases in preclinical studies. In particular, CEST MRI has been exploited for assessing the acid-base homeostasis in the kidney and for monitoring pH changes in several disease models. This review summarizes several CEST MRI procedures for assessing kidney functionality and pH, for monitoring renal pH changes in different kidney injury models and for evaluating renal allograft rejection.This chapter is based upon work from the COST Action PARENCHIMA, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This introduction chapter is complemented by two separate chapters describing the experimental procedure and data analysis.

scholarly journals A method for accurate pH mapping with chemical exchange saturation transfer (CEST) MRI

2015 ◽  
Vol 11 (3) ◽  
pp. 195-202 ◽  
Author(s):  
Phillip Zhe Sun ◽  
Gang Xiao ◽  
Iris Yuwen Zhou ◽  
Yingkun Guo ◽  
Renhua Wu
Keyword(s):  
Chemical Exchange ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer ◽  
Cest Mri

Progress toward quantitative in vivo chemical exchange saturation transfer (CEST) MRI

2017 ◽  
Vol 57 (9) ◽  
pp. 809-824 ◽  
Author(s):  
Yang Ji ◽  
Iris Yuwen Zhou ◽  
Bensheng Qiu ◽  
Phillip Zhe Sun
Keyword(s):  
Chemical Exchange ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer ◽  
Cest Mri
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