q-space MR imaging of gastric carcinoma ex vivo: Correlation with histopathologic findings

2015 ◽  
Vol 76 (2) ◽  
pp. 602-612 ◽  
Author(s):  
Ichiro Yamada ◽  
Keigo Hikishima ◽  
Naoyuki Miyasaka ◽  
Keiji Kato ◽  
Eisaku Ito ◽  
...  
Radiology ◽  
2015 ◽  
Vol 275 (3) ◽  
pp. 841-848 ◽  
Author(s):  
Ichiro Yamada ◽  
Naoyuki Miyasaka ◽  
Keigo Hikishima ◽  
Keiji Kato ◽  
Kazuyuki Kojima ◽  
...  

2016 ◽  
Vol 34 (2) ◽  
pp. 144-151 ◽  
Author(s):  
Ichiro Yamada ◽  
Keigo Hikishima ◽  
Naoyuki Miyasaka ◽  
Keiji Kato ◽  
Kazuyuki Kojima ◽  
...  

2015 ◽  
Vol 33 (4) ◽  
pp. 413-419 ◽  
Author(s):  
Ichiro Yamada ◽  
Naoyuki Miyasaka ◽  
Keigo Hikishima ◽  
Yutaka Tokairin ◽  
Tatsuyuki Kawano ◽  
...  

2018 ◽  
Vol 43 (7) ◽  
pp. 1524-1530 ◽  
Author(s):  
Akitoshi Inoue ◽  
Shinichi Ohta ◽  
Norihisa Nitta ◽  
Masahiro Yoshimura ◽  
Hiromichi Sonoda ◽  
...  

2021 ◽  
Vol 11 (9) ◽  
pp. 4310
Author(s):  
Pietro Valerio Foti ◽  
Corrado Inì ◽  
Mario Travali ◽  
Renato Farina ◽  
Stefano Palmucci ◽  
...  

Background: Currently, radiotherapy represents the most widely employed therapeutic option in patients with uveal melanoma. Although the effects of proton beam radiotherapy on uveal melanoma end ocular tissues have been histologically documented, their appearance at MR imaging is still poorly understood. The purpose of our study was to elucidate the magnetic resonance (MR) semiotics of radiotherapy-induced changes to neoplastic tissues and ocular structures in patients with uveal melanoma undergoing secondary enucleation after proton beam radiotherapy. Methods: Nine patients with uveal melanoma who had undergone proton beam radiotherapy, MR imaging, and subsequent secondary enucleation were retrospectively selected. The histopathologic findings evaluated for irradiated tumors were necrosis, fibrosis, and viable tumor, while the histopathologic findings evaluated for extratumoral ocular/periocular tissues were radiation-related intraocular inflammation, vitreous hemorrhage, optic nerve degeneration, iris neovascularization, and periocular fibrotic adhesions. On MR images, the appearance of the abovementioned histologic features was assessed on conventional and diffusion-weighted sequences. Results: T2-weighted sequences performed better in detecting radiation-induced necrosis, fibrosis, optic nerve degeneration, and periocular fibrotic adhesions. T1-weighted sequences were preferable for identifying cataracts, vitreous hemorrhage, and inflammatory complications. Contrast-enhanced T1-weighted sequences were irreplaceable in assessing iris neovascularization, and in confirming inflammatory complications. Conclusions: In the light of their increasing role in the multidisciplinary management of patients with uveal melanoma, radiologists should be aware of the MR appearance of the effects of radiotherapy on neoplastic and ocular tissue, in order to improve the accuracy of follow-up MR examinations.


1995 ◽  
Vol 36 (2) ◽  
pp. 163-167 ◽  
Author(s):  
H. Honda ◽  
H. Onitsuka ◽  
Y. Kanazawa ◽  
T. Matsumata ◽  
T. Hayashi ◽  
...  

In order to clarify the factors contributing to the signal intensities (SIs) of HCC on T1-weighted images, the amount of water, lipid, copper (Cu), iron (Fe), and manganese (Mn) was determined in HCC and surrounding hepatic parenchyma of 13 patients. The relationships among these findings, the histopathologic findings, and the SIs of T1-weighted images were evaluated. Among the 13 HCC, 3 had a high SI, 5 were isointense, and 5 had a low SI on T1-weighted images compared to the surrounding hepatic parenchyma. The paramagnetic ions which contributed to the SI patterns were assumed to be Cu in HCC (38.0±62.4 μg/g ww), and Fe in the liver (61.1±42.4 μg/g ww) and HCC (40.0±34.3 μg/g ww). In 8 HCC with high- or isointensity, 2 were grades I, 5 were grade II, and one was grade III according to the Edmondson-Steiner's histopathologic classification. It is concluded that the SI patterns alone can not be a sign of low grade malignancy because of the existence of Fe in livers and HCC.


Radiology ◽  
2016 ◽  
Vol 279 (2) ◽  
pp. 385-394 ◽  
Author(s):  
Allyson L. Chesebro ◽  
Nicole S. Winkler ◽  
Robyn L. Birdwell ◽  
Catherine S. Giess

2008 ◽  
Vol 28 (6) ◽  
pp. 1435-1443 ◽  
Author(s):  
Miki Kobayashi ◽  
Hiroko Kawashima ◽  
Osamu Matsui ◽  
Yoh Zen ◽  
Masayuki Suzuki ◽  
...  

1997 ◽  
Vol 15 (4) ◽  
pp. 469-474 ◽  
Author(s):  
Mario Mascalchi ◽  
Xian-Nu Jin ◽  
Cristiana Agen ◽  
Pasquale Petruzzi ◽  
Denise Nardini ◽  
...  
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