In vivo magnetization transfer imaging of the lung using a zero echo time sequence at 4.7 Tesla in mice: Initial experience

2015 ◽  
Vol 76 (1) ◽  
pp. 156-162 ◽  
Author(s):  
Moritz C. Wurnig ◽  
Markus Weiger ◽  
Mingming Wu ◽  
David Kenkel ◽  
Wolfgang Jungraithmayr ◽  
...  
Keyword(s):  
Magnetization Transfer ◽  
Time Sequence ◽  
Magnetization Transfer Imaging ◽  
Initial Experience ◽  
Echo Time

Use of magnetization transfer imaging in vivo to investigate the neuropathology in schizophrenia

1998 ◽  
Vol 29 (1-2) ◽  
pp. 80 ◽  
Author(s):  
J. Foong ◽  
M. Maier ◽  
G. Barker ◽  
D.H. Miller ◽  
M.A. Ron
Keyword(s):  
Magnetization Transfer ◽  
Magnetization Transfer Imaging

In vivo evaluation of remyelination in rat brain by magnetization transfer imaging

2000 ◽  
Vol 178 (1) ◽  
pp. 10-16 ◽  
Author(s):  
M.S.A Deloire-Grassin ◽  
B Brochet ◽  
B Quesson ◽  
C Delalande ◽  
V Dousset ◽  
...  
Keyword(s):  
Rat Brain ◽  
Magnetization Transfer ◽  
Magnetization Transfer Imaging ◽  
In Vivo Evaluation

Optic nerve magnetization transfer imaging and measures of axonal loss and demyelination in optic neuritis

2007 ◽  
Vol 13 (7) ◽  
pp. 875-879 ◽  
Author(s):  
SA Trip ◽  
PG Schlottmann ◽  
SJ Jones ◽  
W-Y. Li ◽  
DF Garway-Heath ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Optic Neuritis ◽  
Magnetization Transfer ◽  
Quantitative Information ◽  
Magnetization Transfer Ratio ◽  
Central Field ◽  
Axonal Loss ◽  
Magnetization Transfer Imaging ◽  
Vep Latency

Magnetization transfer imaging is an MRI technique that provides quantitative information about in vivo tissue integrity, including myelin and axonal content, and is expressed as the magnetization transfer ratio (MTR). The optic neuritis lesion can model the MS lesion in vivo and permits use of non-invasive markers of optic nerve myelination (visual evoked potential [VEP] latency) and retinal neuroaxonal loss (optical coherence tomography [OCT]) to provide further information about the in vivo substrates of optic nerve MTR. Twenty-five patients with optic neuritis were studied using an optic nerve MTR sequence, quantitative visual function testing, VEPs and OCT, along with 15 controls. MTR was reduced in affected nerves compared to both clinically unaffected nerves from patients and control nerves ( P < 0.001). Whole-nerve MTR correlated modestly with central-field VEP latency but more strongly when lesion-only MTR was measured, when a modest correlation with whole-field VEP latency emerged. OCT-quantified retinal neuroaxonal loss also correlated with MTR. In conclusion, markers of optic nerve myelination and axonal loss both correlate with optic nerve MTR. Because axonal loss following optic neuritis also results in myelin loss, the relative contributions of the two pathological conditions to the MTR measures cannot be estimated from this study. Multiple Sclerosis 2007; 13: 875—879. http://msj.sagepub.com

In vivo quantitative magnetization transfer imaging correlates with histology during de- and remyelination in cuprizone-treated mice

2015 ◽  
Vol 28 (3) ◽  
pp. 327-337 ◽  
Author(s):  
Laura Turati ◽  
Marco Moscatelli ◽  
Alfonso Mastropietro ◽  
Nicholas G. Dowell ◽  
Ileana Zucca ◽  
...  
Keyword(s):  
Magnetization Transfer ◽  
Magnetization Transfer Imaging
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