In vivo double quantum filtered sodium magnetic resonance imaging of human brain

2014 ◽  
Vol 73 (2) ◽  
pp. 497-504 ◽  
Author(s):  
Adrian Tsang ◽  
Robert W. Stobbe ◽  
Christian Beaulieu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Human Brain ◽  
Double Quantum ◽  
Resonance Imaging

Identification and Morphologic Assessment of Mesocoelic Recess by In Vivo Human Brain Imaging With 7.0-T Magnetic Resonance Imaging

2011 ◽  
Vol 35 (4) ◽  
pp. 486-491 ◽  
Author(s):  
Na Rae Kim ◽  
Je G. Chi ◽  
Sang Han Choi ◽  
Young-Bo Kim ◽  
Hee Young Hwang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Human Brain ◽  
Brain Imaging ◽  
Resonance Imaging

scholarly journals Depth-dependent intracortical myelin organization in the living human brain determined by in vivo ultra-high field magnetic resonance imaging

NeuroImage ◽  
2019 ◽  
Vol 185 ◽  
pp. 27-34 ◽  
Author(s):  
Emma Sprooten ◽  
Rafael O'Halloran ◽  
Juliane Dinse ◽  
Won Hee Lee ◽  
Dominik Andreas Moser ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Human Brain ◽  
High Field ◽  
Resonance Imaging ◽  
Ultra High Field

In Vivo Magnetic Resonance Imaging and 31P Spectroscopy of Large Human Brain Tumours at 1.5 Tesla

1988 ◽  
Vol 29 (1) ◽  
pp. 77-82 ◽  
Author(s):  
C. Thomsen ◽  
K. E. Jensen ◽  
E. Achten ◽  
O. Henriksen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Human Brain ◽  
Brain Tumours ◽  
Surface Coil ◽  
Normal Brain ◽  
Resonance Imaging ◽  
Before And After ◽  
Human Brain Tumours

31P MR spectroscopy of human brain tumours is one feature of magnetic resonance imaging. Eight patients with large superficial brain tumours and eight healthy volunteers were examined with 31P spectroscopy using an 8 cm surface coil for volume selection. Seven frequencies were resolved in our spectra. The spectra from patients with brain tumours showed a great scatter, but generally they overlapped those obtained in normal brain tissue. No characteristic pattern of the spectra was seen in the tumours. One patient with a metastasis from a small cell carcinoma of the lung was examined before and after chemotherapy. The spectra showed considerable changes during chemotherapy. It is concluded that 31P spectroscopy using surface coils is of limited value for tumour characterization, but may add useful information in monitoring the effect of chemotherapy.

scholarly journals Imaging Multiple Sclerosis Pathology at 160μm Isotropic Resolution by Human Whole-Brain Ex Vivo Magnetic Resonance Imaging at 3T

2021 ◽  
Author(s):  
Weigel Matthias ◽  
Dechent Peter ◽  
Galbusera Riccardo ◽  
Bahn Erik ◽  
Nair Govind ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Human Brain ◽  
Ex Vivo ◽  
Molecular Layer ◽  
Cortical Lesion ◽  
Resonance Imaging ◽  
Whole Brain

AbstractPostmortem magnetic resonance imaging (MRI) of the fixed healthy and diseased human brain facilitates spatial resolutions and image quality that is not achievable with in vivo MRI scans. Though challenging - and almost exclusively performed at 7T field strength - depicting the tissue architecture of the entire brain in fine detail is invaluable since it enables the study of neuroanatomy and uncovers important pathological features in neurological disorders. The objectives of the present work were (i) to develop a 3D isotropic ultra-high-resolution imaging approach for human whole-brain ex vivo acquisitions working on a standard clinical 3T MRI system, and (ii) to explore the sensitivity and specificity of this concept for specific pathoanatomical features of multiple sclerosis. The reconstructed images demonstrate unprecedented resolution and soft tissue contrast of the diseased human brain at 3T, thus allowing visualization of sub-millimetric lesions in the different cortical layers and in the cerebellar cortex, as well as unique cortical lesion characteristics such as the presence of incomplete / complete iron rims, and patterns of iron accumulation. Further details such as the subpial molecular layer, the line of Gennari, and some intrathalamic nuclei are also well distinguishable.

Anisotropy of spin-echo T 2 relaxation by magnetic resonance imaging in the human brain in vivo

2015 ◽  
Vol 4 (3) ◽  
pp. 299-310 ◽  
Author(s):  
Michael J. Knight ◽  
Bryony Wood ◽  
Elizabeth Couthard ◽  
Risto Kauppinen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Human Brain ◽  
Spin Echo ◽  
Resonance Imaging

Direct visualization of Parkinson's disease by in vivo human brain imaging using 7.0T magnetic resonance imaging

2011 ◽  
Vol 26 (4) ◽  
pp. 713-718 ◽  
Author(s):  
Zang-Hee Cho ◽  
Se-Hong Oh ◽  
Jong-Min Kim ◽  
Sung-Yeon Park ◽  
Dae-Hyuk Kwon ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Magnetic Resonance ◽  
Human Brain ◽  
Brain Imaging ◽  
Direct Visualization ◽  
Resonance Imaging

scholarly journals Imaging multiple sclerosis pathology at 160 μm isotropic resolution by human whole-brain ex vivo magnetic resonance imaging at 3 T

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Matthias Weigel ◽  
Peter Dechent ◽  
Riccardo Galbusera ◽  
Erik Bahn ◽  
Govind Nair ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Human Brain ◽  
Ex Vivo ◽  
Molecular Layer ◽  
Cortical Lesion ◽  
Resonance Imaging ◽  
Whole Brain

AbstractPostmortem magnetic resonance imaging (MRI) of the fixed healthy and diseased human brain facilitates spatial resolutions and image quality that is not achievable with in vivo MRI scans. Though challenging—and almost exclusively performed at 7 T field strength—depicting the tissue architecture of the entire brain in fine detail is invaluable since it enables the study of neuroanatomy and uncovers important pathological features in neurological disorders. The objectives of the present work were (1) to develop a 3D isotropic ultra-high-resolution imaging approach for human whole-brain ex vivo acquisitions working on a standard clinical 3 T MRI system; and (2) to explore the sensitivity and specificity of this concept for specific pathoanatomical features of multiple sclerosis. The reconstructed images demonstrate unprecedented resolution and soft tissue contrast of the diseased human brain at 3 T, thus allowing visualization of sub-millimetric lesions in the different cortical layers and in the cerebellar cortex, as well as unique cortical lesion characteristics such as the presence of incomplete/complete iron rims, and patterns of iron accumulation. Further details such as the subpial molecular layer, the line of Gennari, and some intrathalamic nuclei are also well distinguishable.

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