scholarly journals Accelerated whole-heart coronary MRA using motion-corrected sensitivity encoding with three-dimensional projection reconstruction

2014 ◽  
Vol 73 (1) ◽  
pp. 284-291 ◽  
Author(s):  
Jianing Pang ◽  
Behzad Sharif ◽  
Reza Arsanjani ◽  
Xiaoming Bi ◽  
Zhaoyang Fan ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Projection Reconstruction ◽  
Coronary Mra ◽  
Sensitivity Encoding ◽  
Whole Heart

scholarly journals Whole-heart coronary MRA with 100% respiratory gating efficiency: Self-navigated three-dimensional retrospective image-based motion correction (TRIM)

2013 ◽  
Vol 71 (1) ◽  
pp. 67-74 ◽  
Author(s):  
Jianing Pang ◽  
Himanshu Bhat ◽  
Behzad Sharif ◽  
Zhaoyang Fan ◽  
Louise E. J. Thomson ◽  
...  
Keyword(s):  
Motion Correction ◽  
Respiratory Gating ◽  
Three Dimensional ◽  
Coronary Mra ◽  
Whole Heart

scholarly journals Motion corrected sensitivity encoded isotropic projection reconstruction (SNIPR) for whole-heart coronary MRA

2013 ◽  
Vol 15 (S1) ◽  
Author(s):  
Jianing Pang ◽  
Behzad Sharif ◽  
Reza Arsanjani ◽  
Louise E Thomson ◽  
John D Friedman ◽  
...  
Keyword(s):  
Projection Reconstruction ◽  
Coronary Mra ◽  
Whole Heart ◽  
Isotropic Projection

Three-dimensional breathhold SSFP coronary MRA: A comparison between 1.5T and 3.0T

2005 ◽  
Vol 22 (2) ◽  
pp. 206-212 ◽  
Author(s):  
Xiaoming Bi ◽  
Vibhas Deshpande ◽  
Orlando Simonetti ◽  
Gerhard Laub ◽  
Debiao Li
Keyword(s):  
Three Dimensional ◽  
Coronary Mra

Abstract 2806: Whole Heart Coronary Magnetic Resonance Angiography Using 32-Channel Cardiac Coils and High Parallel Imaging Factor

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Motonori Nagata ◽  
Hajime Sakuma ◽  
Nanaka Ishida ◽  
Hiroshi Nakajima ◽  
Masaki Ishida ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Angiography ◽  
Parallel Imaging ◽  
Noninvasive Detection ◽  
Acquisition Time ◽  
Luminal Diameter ◽  
X Ray ◽  
Coronary Mra ◽  
Imaging Time ◽  
Whole Heart

PURPOSE Coronary MRA provides noninvasive detection of coronary artery disease (CAD) without administration of contrast medium or exposing the patient to radiation. However, use of coronary MRA in excluding patients with CAD has been limited due to lengthy imaging time. The purpose of this study was to reduce acquisition time of coronary MRA by using 32 channel cardiac coils and high parallel imaging factor, and to evaluate diagnostic performance of this method in detecting significant CAD. METHOD AND MATERIALS Sixty-two patients with suspected CAD were studied. Free-breathing coronary MRA encompassing the entire heart was acquired by using 32-channel coils and SENSE factor of 4. After monitoring motion of the coronary artery on cine MRI, MR angiograms were acquired during diastole in 46 patients (acquisition window 82±57ms) and during systole in 16 patients (50±19ms). Coronary MRA images were interpreted by 2 observers by employing a sliding SLAB MIP method. All patients underwent X-ray coronary angiography within 4 weeks from MRA, and significant CAD was defined as a luminal diameter reduction of 50% or more by QCA. All lesions with a reference diameter of 2mm or more on X-ray angiography were included when determining the accuracy of coronary MRA. RESULTS Acquisition of MRA was completed in all 62 patients, with the averaged imaging time of 6.1±2.6min. High SENSE factor achieved by 32-channel coils resulted in substantial reduction of imaging time by factor of >2, with the image quality score (4.6±0.2) at least equivalent to that by conventional 5-channel coils and SENSE factor of 2 (4.5±0.2). Significant CAD was observed on X-ray coronary angiography in 39 patients. MRA detected 33(85%) of 39 patients having CAD, with high specificity of 96%(22/23). All 16 patients with double- or triple-vessel diseases were detected by MRA. On a vessel based analysis, Whole-heart coronary MRA demonstrated sensitivity of 83%(49/59), specificity of 94%(119/127) and NPV of 92%(119/129). CONCLUSION Whole-heart coronary MRA with 1.5T MR imager and 32-chennel coils permits noninvasive detection of CAD with substantially reduced imaging time and high study success rate. High NPV (>90%) indicated the value of this approach in ruling out significant CAD.

scholarly journals Three-dimensional alignment of microvasculature and cardiomyocytes in the developing ventricle

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Maryse Lapierre-Landry ◽  
Hana Kolesová ◽  
Yehe Liu ◽  
Michiko Watanabe ◽  
Michael W. Jenkins
Keyword(s):  
Coronary Artery ◽  
Normal Development ◽  
Fluorescent Dyes ◽  
Developmental Stages ◽  
Three Dimensional ◽  
Left Ventricular ◽  
Vessel Density ◽  
Ventricular Wall ◽  
Major Coronary Artery ◽  
Whole Heart

Abstract While major coronary artery development and pathologies affecting them have been extensively studied, understanding the development and organization of the coronary microvasculature beyond the earliest developmental stages requires new tools. Without techniques to image the coronary microvasculature over the whole heart, it is likely we are underestimating the microvasculature’s impact on normal development and diseases. We present a new imaging and analysis toolset to visualize the coronary microvasculature in intact embryonic hearts and quantify vessel organization. The fluorescent dyes DiI and DAPI were used to stain the coronary vasculature and cardiomyocyte nuclei in quail embryo hearts during rapid growth and morphogenesis of the left ventricular wall. Vessel and cardiomyocytes orientation were automatically extracted and quantified, and vessel density was calculated. The coronary microvasculature was found to follow the known helical organization of cardiomyocytes in the ventricular wall. Vessel density in the left ventricle did not change during and after compaction. This quantitative and automated approach will enable future cohort studies to understand the microvasculature’s role in diseases such as hypertrophic cardiomyopathy where misalignment of cardiomyocytes has been observed in utero.

Evaluation of three-dimensional navigator-gated whole heart MR coronary angiography: The importance of systolic imaging in subjects with high heart rates

2007 ◽  
Vol 61 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Yen-Wen Wu ◽  
Eiji Tadamura ◽  
Masaki Yamamuro ◽  
Shotaro Kanao ◽  
Kazuki Nakayama ◽  
...  
Keyword(s):  
Coronary Angiography ◽  
Three Dimensional ◽  
Heart Rates ◽  
Mr Coronary Angiography ◽  
Whole Heart
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