scholarly journals Bone marrow fat quantification in the presence of trabecular bone: Initial comparison between water-fat imaging and single-voxel MRS

2013 ◽  
Vol 71 (3) ◽  
pp. 1158-1165 ◽  
Author(s):  
Dimitrios C. Karampinos ◽  
Gerd Melkus ◽  
Thomas Baum ◽  
Jan S. Bauer ◽  
Ernst J. Rummeny ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Trabecular Bone ◽  
Marrow Fat ◽  
Fat Quantification ◽  
Bone Marrow Fat ◽  
Single Voxel ◽  
Initial Comparison

scholarly journals Validation of bone marrow fat quantification in the presence of trabecular bone using MRI

2014 ◽  
Vol 42 (2) ◽  
pp. 539-544 ◽  
Author(s):  
Christina S. Gee ◽  
Jennifer T.K. Nguyen ◽  
Candice J. Marquez ◽  
Julia Heunis ◽  
Andrew Lai ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Trabecular Bone ◽  
Marrow Fat ◽  
Fat Quantification ◽  
Bone Marrow Fat

The need forT2correction on MRS-based vertebral bone marrow fat quantification: implications for bone marrow fat fraction age dependence

2015 ◽  
Vol 28 (4) ◽  
pp. 432-439 ◽  
Author(s):  
Michael Dieckmeyer ◽  
Stefan Ruschke ◽  
Christian Cordes ◽  
Samuel P. Yap ◽  
Hendrik Kooijman ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Age Dependence ◽  
Marrow Fat ◽  
Fat Quantification ◽  
Vertebral Bone ◽  
Bone Marrow Fat ◽  
Fat Fraction ◽  
Vertebral Bone Marrow

Bone marrow fat quantification of osteoporotic vertebral compression fractures: comparison of multi-voxel proton MR spectroscopy and chemical-shift gradient-echo MR imaging

2011 ◽  
Vol 52 (9) ◽  
pp. 1032-1036 ◽  
Author(s):  
Anne Régis-Arnaud ◽  
Boris Guiu1 ◽  
Paul-Michael Walker ◽  
Denis Krausé ◽  
Frédéric Ricolfi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Mr Imaging ◽  
Phase Method ◽  
Vertebral Compression Fractures ◽  
Gradient Echo ◽  
Marrow Fat ◽  
Fat Quantification ◽  
Compression Fractures ◽  
Bone Marrow Fat ◽  
Fat Fraction

Background Only a few studies have used in/opposed phase method for a quantitative evaluation of fat fraction in the spine. Purpose To compare multivoxel proton MR spectroscopy and chemical-shift gradient-echo MR imaging for bone marrow fat quantification in vertebral compression fractures (VCF). Material and Methods Vertebral marrow fat quantification in fifteen patients was measured at 3.0-T. Multi-voxel proton spectroscopy (MRS) and in/opposed-phase MR imaging using a fat map build with a triple-echo gradient-echo sequence was used. All the patients had benign vertebral collapse. Bone marrow fat content was evaluated by both techniques in compressed (acute or chronic) and in non-compressed vertebrae. Results The percentage of fat fraction measured by the triple-echo sequence was well correlated with those calculated by MRS ( r2 = 0.85; P < 10−4). There was a significant decrease of fat fraction in acute VCF versus both chronic VCF ( P < 10−9) and non-fractured vertebrae ( P < 10−7). There was no significant difference in fat fraction evaluated by both techniques between non-fractured vertebrae and chronic VCF. Conclusion We have validated the in/opposed phase method compared with MRS for vertebral bone marrow fat quantification. The fat mapping using a triple-echo gradient-echo sequence allows distinguishing acute and chronic benign VCF.

Modeling of T 2 * decay in vertebral bone marrow fat quantification

2015 ◽  
Vol 28 (11) ◽  
pp. 1535-1542 ◽  
Author(s):  
Dimitrios C. Karampinos ◽  
Stefan Ruschke ◽  
Michael Dieckmeyer ◽  
Holger Eggers ◽  
Hendrik Kooijman ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Marrow Fat ◽  
Fat Quantification ◽  
Vertebral Bone ◽  
Bone Marrow Fat ◽  
Vertebral Bone Marrow

scholarly journals Association of MRS-Based Vertebral Bone Marrow Fat Fraction with Bone Strength in a Human In Vitro Model

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Dimitrios C. Karampinos ◽  
Stefan Ruschke ◽  
Olga Gordijenko ◽  
Eduardo Grande Garcia ◽  
Hendrik Kooijman ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Biomechanical Testing ◽  
Marrow Fat ◽  
Bone Marrow Fat ◽  
Single Voxel ◽  
Microstructure Parameters ◽  
Human Cadavers ◽  
Fat Fraction ◽  
Vitro Model

Bone marrow adiposity has recently gained attention due to its association with bone loss pathophysiology. In this study, ten vertebrae were harvested from fresh human cadavers. Trabecular BMD and microstructure parameters were extracted from MDCT. Bone marrow fat fractions were determined using single-voxel MRS. Failure load (FL) values were assessed by destructive biomechanical testing. Significant correlations (P<0.05) were observed between MRS-based fat fraction and MDCT-based parameters (up tor=-0.72) and MRS-based fat fraction and FL (r=-0.77). These findings underline the importance of the bone marrow in the pathophysiology and imaging diagnostics of osteoporosis.

scholarly journals Dual-Energy Computed Tomography for Fat Quantification in the Liver and Bone Marrow: A Literature Review

2020 ◽  
Vol 192 (12) ◽  
pp. 1137-1153
Author(s):  
Isabel Molwitz ◽  
Miriam Leiderer ◽  
Cansu Özden ◽  
Jin Yamamura
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Bone Marrow ◽  
Hepatic Steatosis ◽  
Bone Mineral ◽  
Mineral Density ◽  
Marrow Fat ◽  
Fat Quantification ◽  
Bone Marrow Fat ◽  
Contrast Enhanced Ct

Background With dual-energy computed tomography (DECT) it is possible to quantify certain elements and tissues by their specific attenuation, which is dependent on the X-ray spectrum. This systematic review provides an overview of the suitability of DECT for fat quantification in clinical diagnostics compared to established methods, such as histology, magnetic resonance imaging (MRI) and single-energy computed tomography (SECT). Method Following a systematic literature search, studies which validated DECT fat quantification by other modalities were included. The methodological heterogeneity of all included studies was processed. The study results are presented and discussed according to the target organ and specifically for each modality of comparison. Results Heterogeneity of the study methodology was high. The DECT data was generated by sequential CT scans, fast-kVp-switching DECT, or dual-source DECT. All included studies focused on the suitability of DECT for the diagnosis of hepatic steatosis and for the determination of the bone marrow fat percentage and the influence of bone marrow fat on the measurement of bone mineral density. Fat quantification in the liver and bone marrow by DECT showed valid results compared to histology, MRI chemical shift relaxometry, magnetic resonance spectroscopy, and SECT. For determination of hepatic steatosis in contrast-enhanced CT images, DECT was clearly superior to SECT. The measurement of bone marrow fat percentage via DECT enabled the bone mineral density quantification more reliably. Conclusion DECT is an overall valid method for fat quantification in the liver and bone marrow. In contrast to SECT, it is especially advantageous to diagnose hepatic steatosis in contrast-enhanced CT examinations. In the bone marrow DECT fat quantification allows more valid quantification of bone mineral density than conventional methods. Complementary studies concerning DECT fat quantification by split-filter DECT or dual-layer spectral CT and further studies on other organ systems should be conducted. Key points: Citation Format

Bone marrow fat is metabolically distinct fat depot

2013 ◽  
Author(s):  
Riku Kiviranta ◽  
Tam Pham ◽  
Jarna Hannukainen ◽  
Juho Jarvelin ◽  
Anna Karmi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Marrow Fat ◽  
Bone Marrow Fat ◽  
Fat Depot
Sign in / Sign up

Export Citation Format

Share Document