Effect of formalin fixation on biexponential modeling of diffusion decay in prostate tissue

2012 ◽  
Vol 70 (4) ◽  
pp. 1160-1166 ◽  
Author(s):  
Roger Bourne ◽  
Andre Bongers ◽  
Ned Charles ◽  
Carl Power ◽  
Paul Sved ◽  
...  
Keyword(s):  
Formalin Fixation ◽  
Prostate Tissue ◽  
Diffusion Decay

scholarly journals Biexponential diffusion decay in formalin-fixed prostate tissue: Preliminary findings

2011 ◽  
Vol 68 (3) ◽  
pp. 954-959 ◽  
Author(s):  
Roger M. Bourne ◽  
Nyoman Kurniawan ◽  
Gary Cowin ◽  
Timothy Stait-Gardner ◽  
Paul Sved ◽  
...  
Keyword(s):  
Prostate Tissue ◽  
Diffusion Decay ◽  
Formalin Fixed

scholarly journals Biexponential characterization of prostate tissue water diffusion decay curves over an extended b-factor range

2006 ◽  
Vol 24 (5) ◽  
pp. 563-568 ◽  
Author(s):  
Robert V. Mulkern ◽  
Agnieszka Szot Barnes ◽  
Steven J. Haker ◽  
Yin P. Hung ◽  
Frank J. Rybicki ◽  
...  
Keyword(s):  
Water Diffusion ◽  
Prostate Tissue ◽  
Tissue Water ◽  
Diffusion Decay

Optimal formalin fixation and processing schedule of cell blocks from fine needle aspirates

Pathology ◽  
1989 ◽  
Vol 21 (2) ◽  
pp. 143-145 ◽  
Author(s):  
Ignatius T.M. Kung ◽  
Rose W.S. Yuen ◽  
John K.C. Chan
Keyword(s):  
Formalin Fixation ◽  
Fine Needle ◽  
Fine Needle Aspirates

The silent presence of Mycoplasma hominis in patients with prostate cancer

2020 ◽  
Vol 78 (7) ◽  
Author(s):  
Saman Saadat ◽  
Pezhman Karami ◽  
Mohammad Jafari ◽  
Mahdi Kholoujini ◽  
Zahra Rikhtegaran Tehrani ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Mycoplasma Hominis ◽  
Opportunistic Pathogen ◽  
Host Cells ◽  
Prostate Tissue ◽  
Control Group ◽  
P Value ◽  
Retrospective Case ◽  
Formalin Fixed Paraffin Embedded ◽  
Pcr Targeting

ABSTRACT Background Mycoplasma hominis, an opportunistic pathogen in human genitourinary tract, can cause chronic infection in the prostate. Intracellular survival of M. hominis leads to a prolonged presence in the host cells that can affect the cell's biological cycle. In the present study, we aimed to evaluate the frequency of M. hominis DNA in prostate tissue of Iranian patients with prostate cancer (PCa) in comparison to a control group with benign prostatic hyperplasia (BPH). Methods This research was a retrospective case-control study using 61 archived formalin-fixed paraffin-embedded (FFPE) blocks of prostate tissue from patients with PCa and 70 FFPE blocks of patients with BPH. Real-time PCR, targeting two different genes, 16S rRNA and yidC, in the M. hominis genome was performed for all specimens. Results Out of 61 blocks of prostate biopsy from patients with PCa, eight samples (13%) were positive for M. hominis, while the bacterium was not detected in any of the 70 blocks of patients with BPH (P value, 0.002). Conclusions The high frequency of M. hominis in patients with PCa likely shows a hidden role of the organism in prostate cancer during its chronic, apparently silent and asymptomatic colonization in prostate.

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