scholarly journals Prospective high‐resolution respiratory‐resolved whole‐heart MRI for image‐guided cardiovascular interventions

2011 ◽  
Vol 68 (1) ◽  
pp. 205-213 ◽  
Author(s):  
Christoph Kolbitsch ◽  
Claudia Prieto ◽  
Christian Buerger ◽  
James Harrison ◽  
Reza Razavi ◽  
...  
Keyword(s):  
High Resolution ◽  
Image Guided ◽  
Whole Heart ◽  
Cardiovascular Interventions

TH-C-210A-04: New High Resolution Dynamic Detectors and Flow Modifying Stents for Neuro-Endovascular Image Guided Interventions

2009 ◽  
Vol 36 (6Part27) ◽  
pp. 2805-2806
Author(s):  
S Rudin ◽  
CN Ionita ◽  
A Kuhls-Gilcrist ◽  
A Jain ◽  
C Keleshis ◽  
...  
Keyword(s):  
High Resolution ◽  
Image Guided

scholarly journals Respiratory motion-compensated high-resolution 3D whole-heart T1ρ mapping

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Haikun Qi ◽  
Aurelien Bustin ◽  
Thomas Kuestner ◽  
Reza Hajhosseiny ◽  
Gastao Cruz ◽  
...  
Keyword(s):  
High Resolution ◽  
Respiratory Motion ◽  
T1ρ Mapping ◽  
Whole Heart

scholarly journals Accelerated high-resolution free-breathing 3D whole-heart T2-prepared black-blood and bright-blood cardiovascular magnetic resonance

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Teresa Correia ◽  
Giulia Ginami ◽  
Imran Rashid ◽  
Giovanna Nordio ◽  
Reza Hajhosseiny ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Healthy Subjects ◽  
Free Breathing ◽  
Black Blood ◽  
Contrast Injection ◽  
Post Contrast ◽  
Whole Heart ◽  
Bright Blood

Abstract Background The free-breathing 3D whole-heart T2-prepared Bright-blood and black-blOOd phase SensiTive inversion recovery (BOOST) cardiovascular magnetic resonance (CMR) sequence was recently proposed for simultaneous bright-blood coronary CMR angiography and black-blood late gadolinium enhancement (LGE) imaging. This sequence enables simultaneous visualization of cardiac anatomy, coronary arteries and fibrosis. However, high-resolution (< 1.4 × 1.4 × 1.4 mm3) fully-sampled BOOST requires long acquisition times of ~ 20 min. Methods In this work, we propose to extend a highly efficient respiratory-resolved motion-corrected reconstruction framework (XD-ORCCA) to T2-prepared BOOST to enable high-resolution 3D whole-heart coronary CMR angiography and black-blood LGE in a clinically feasible scan time. Twelve healthy subjects were imaged without contrast injection (pre-contrast BOOST) and 10 patients with suspected cardiovascular disease were imaged after contrast injection (post-contrast BOOST). A quantitative analysis software was used to compare accelerated pre-contrast BOOST against the fully-sampled counterpart (vessel sharpness and length of the left and right coronary arteries). Moreover, three cardiologists performed diagnostic image quality scoring for clinical 2D LGE and both bright- and black-blood 3D BOOST imaging using a 4-point scale (1–4, non-diagnostic–fully diagnostic). A two one-sided test of equivalence (TOST) was performed to compare the pre-contrast BOOST images. Nonparametric TOST was performed to compare post-contrast BOOST image quality scores. Results The proposed method produces images from 3.8 × accelerated non-contrast-enhanced BOOST acquisitions with comparable vessel length and sharpness to those obtained from fully- sampled scans in healthy subjects. Moreover, in terms of visual grading, the 3D BOOST LGE datasets (median 4) and the clinical 2D counterpart (median 3.5) were found to be statistically equivalent (p < 0.05). In addition, bright-blood BOOST images allowed for visualization of the proximal and middle left anterior descending and right coronary sections with high diagnostic quality (mean score > 3.5). Conclusions The proposed framework provides high‐resolution 3D whole-heart BOOST images from a single free-breathing acquisition in ~ 7 min.

High-resolution three-dimensional T2-weighted sequence for neuronavigation: a new setup and clinical trial

2005 ◽  
Vol 102 (4) ◽  
pp. 658-663 ◽  
Author(s):  
Jan Gralla ◽  
Raphael Guzman ◽  
Caspar Brekenfeld ◽  
Luca Remonda ◽  
Claus Kiefer
Keyword(s):  
Clinical Trial ◽  
High Resolution ◽  
Clinical Application ◽  
Three Dimensional ◽  
Whole Body ◽  
Low Grade ◽  
Data Set ◽  
Content Type ◽  
Image Guided ◽  
Fine Print

Object. Conventional imaging for neuronavigation is performed using high-resolution computerized tomography (CT) scanning or a T1-weighted isovoxel magnetic resonance (MR) sequence. The extension of some lesions, however, is depicted much better on T2-weighted MR images. A possible fusion process used to match low-resolution T2-weighted MR image set with a referenced CT or T1-weighted data set leads to poor resolution in the three-dimensional (3D) reconstruction and decreases accuracy, which is unacceptable for neuronavigation. The object of this work was to develop a 3D T2-weighted isovoxel sequence (3D turbo—spin echo [TSE]) for image-guided neuronavigation of the whole brain and to evaluate its clinical application. Methods. The authors performed a phantom study and a clinical trial on a newly developed T2-weighted isovoxel sequence, 3D TSE, for image-guided neuronavigation using a common 1.5-tesla MR imager (Siemens Sonata whole-body imager). The accuracy study and intraoperative image guidance were performed with the aid of the pointer-based Medtronic Stealth Station Treon. The 3D TSE data set was easily applied to the navigational setup and demonstrated a high registration accuracy during the experimental trial and during an initial prospective clinical trial in 25 patients. The sequence displayed common disposable skin fiducial markers and provided convincing delineation of lesions that appear hyperintense on T2-weighted images such as low-grade gliomas and cavernomas in its clinical application. Conclusions. Three-dimensional TSE imaging broadens the spectrum of navigational and intraoperative data sets, especially for lesions that appear hyperintense on T2-weighted images. The accuracy of its registration is very reliable and it enables high-resolution reconstruction in any orientation, maintaining the advantages of image-guided surgery.

Optical mapping of late myocardial infarction in rats

2006 ◽  
Vol 290 (3) ◽  
pp. H1298-H1306 ◽  
Author(s):  
William R. Mills ◽  
Niladri Mal ◽  
Farhad Forudi ◽  
Zoran B. Popovic ◽  
Marc S. Penn ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Ventricular Tachycardia ◽  
High Resolution ◽  
Action Potentials ◽  
Optical Mapping ◽  
Cellular Heterogeneity ◽  
Artery Ligation ◽  
Conduction Abnormalities ◽  
Mapping Techniques ◽  
Whole Heart

Late myocardial infarction (MI) is associated with ventricular arrhythmias and sudden cardiac death. The exact mechanistic relationship between abnormal cellular electrophysiology, conduction abnormalities, and arrhythmogenesis associated with late MI is not completely understood. We report a novel, rapid dye superfusion technique to enable whole heart, high-resolution optical mapping of late MI. Optical mapping of action potentials was performed in normal rats and rats with anterior MI 7 days after left anterior descending artery ligation. Hearts from normal rats exhibited normal action potentials and impulse conduction. With the use of programmed stimulation to assess arrhythmia inducibility, 29% of hearts with late MI had inducible sustained ventricular tachycardia, compared with 0% in normal rats. A causal relationship between the site of infarction, abnormal action potential conduction (i.e., block and slow conduction), and arrhythmogenesis was observed. Optical mapping techniques can be used to measure high-resolution action potentials in a whole heart model of late MI. This experimental model reproduces many of the electrophysiological characteristics (i.e., conduction slowing, block, and ventricular tachycardia) associated with MI in patients. Importantly, the results of this study can enhance our ability to understand the interplay between cellular heterogeneity, conduction abnormalities, and arrhythmogenesis associated with MI.

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