scholarly journals Low-power adiabatic sequences for in vivo localized two-dimensional chemical shift correlated MR spectroscopy

2010 ◽  
Vol 64 (6) ◽  
pp. 1542-1556 ◽  
Author(s):  
Ovidiu C. Andronesi ◽  
Saadallah Ramadan ◽  
Carolyn E. Mountford ◽  
A.Gregory Sorensen
2010 ◽  
Vol 32 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Aparna Singhal ◽  
Rajakumar Nagarajan ◽  
Charles H. Hinkin ◽  
Rajesh Kumar ◽  
James Sayre ◽  
...  

1992 ◽  
Vol 33 (3) ◽  
pp. 258-261 ◽  
Author(s):  
M. Harada ◽  
H. Nishitani ◽  
K. Koga ◽  
I. Miura ◽  
R. Kido

The metabolism of 5-fluorotryptophan in rat liver was examined by in vivo 19F MR spectroscopy. After i.v. injection of 200 mg/kg b.w. of 5-fluorotryptophan the substance was noted immediately as a strong peak, which decreased gradually. Another peak appeared about 40 min after the injection. The chemical shift value of this peak was 1.6 ppm from that of 5-fluorotryptophan. Kynurenine is known to be a major metabolite of tryptophan in the liver. We synthesized 5-fluorokynurenine from 5-fluorotryptophan by ozonolysis. The chemical shift value of 5-fluorokynurenine was confirmed to be coincident with that of the metabolite peak. This strongly suggests that the metabolite peak of 5-fluorotryptophan observed in this study was the 5-fluorokyrurenine signal. We also applied this method for the CCl4-injured liver. In the liver injury group, the metabolite peak appeared slowly and the intensity was low compared to that of the normal group, though the peak of 5-fluorotryptophan decreased similarly as in the normal liver. These results suggest that the decrease of 5-fluorotryptophan is due mainly to the renal excretion, as the injured liver could not metabolize 5-fluorotryptophan.


2011 ◽  
Vol 43 (5) ◽  
pp. 1570-1575 ◽  
Author(s):  
P. Vyhnanovská ◽  
M. Dezortová ◽  
V. Herynek ◽  
P. Táborský ◽  
O. Viklický ◽  
...  

Radiology ◽  
2009 ◽  
Vol 250 (1) ◽  
pp. 95-102 ◽  
Author(s):  
Boris Guiu ◽  
Jean-Michel Petit ◽  
Romaric Loffroy ◽  
Douraied Ben Salem ◽  
Serge Aho ◽  
...  

2008 ◽  
Vol 60 (2) ◽  
pp. 449-456 ◽  
Author(s):  
Niels Braakman ◽  
Thomas Oerther ◽  
Huub J.M. de Groot ◽  
A. Alia

Radiology ◽  
2011 ◽  
Vol 259 (2) ◽  
pp. 540-549 ◽  
Author(s):  
Saadallah Ramadan ◽  
Ovidiu C. Andronesi ◽  
Peter Stanwell ◽  
Alexander P. Lin ◽  
A. Gregory Sorensen ◽  
...  

2003 ◽  
Vol 49 (4) ◽  
pp. 615-619 ◽  
Author(s):  
Zhiyue J. Wang ◽  
Christina Bergqvist ◽  
Jill V. Hunter ◽  
Dongzhu Jin ◽  
Dah-Jyuu Wang ◽  
...  

2008 ◽  
Vol 21 (6) ◽  
pp. 443-458 ◽  
Author(s):  
M. Albert Thomas ◽  
Thomas Lange ◽  
S. Sendhil Velan ◽  
Rajakumar Nagarajan ◽  
Steve Raman ◽  
...  

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