scholarly journals Quantitative assessment of coronary artery plaque vulnerability by high-resolution magnetic resonance imaging and computational biomechanics: A pilot study ex vivo

2005 ◽  
Vol 54 (6) ◽  
pp. 1360-1368 ◽  
Author(s):  
Jie Zheng ◽  
Issam El Naqa ◽  
Faith E. Rowold ◽  
Thomas K. Pilgram ◽  
Pamela K. Woodard ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Coronary Artery ◽  
Pilot Study ◽  
High Resolution ◽  
Quantitative Assessment ◽  
Ex Vivo ◽  
Resonance Imaging ◽  
Plaque Vulnerability ◽  
Coronary Artery Plaque ◽  
Computational Biomechanics

scholarly journals Ex-vivo Assessment of Coronary Artery Atherosclerosis by Magnetic Resonance Imaging: Correlation with Histopathology

2014 ◽  
Vol 8 (1) ◽  
pp. 26-34
Author(s):  
Everli P. S. Gonçalves Gomes ◽  
Carlos Eduardo Rochitte ◽  
Clerio F. Azevedo ◽  
Pedro A. Lemos ◽  
Paulo Sampaio Gutierrez ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Coronary Artery ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Ex Vivo ◽  
Mean Difference ◽  
Resonance Imaging ◽  
Limits Of Agreement ◽  
Coronary Artery Atherosclerosis ◽  
Good Agreement

Introduction:In recent years, high-resolution magnetic resonance imaging (MRI) has emerged as a very promising technique for studying atherosclerotic disease in humans.Aim:In the present study we sought to determine whether MRI allowed for the morphological characterization of the coronary vessel wall and atherosclerotic plaques using histopathological assessment as the reference standard.Methods:The study population consisted of 13 patients who died of acute myocardial infarction and underwent autopsy. The proximal portions of the coronary arteries were excised and were evaluated both by MRI and by histopathology. For each arterial segment, the following parameters were calculated through manual planimetry: 1. total vessel area (TVA); 2. luminal area (LA) and 3. plaque area (PA).Results:A total of 207 coronary artery cross-sections were found to be suitable for analysis by both MRI and histopathology and were included in the final analyses. Both methods demonstrated moderate to good agreement for the quantification of TVA (mean difference = 2.4±2.4 mm2, 95‰ limits of agreement from -2.4 to +7.2 mm2; CCC = 0.69, 95‰ CI from 0.63 to 0.75), LA (mean difference = 0.0±1.7 mm2, 95‰ limits of agreement from -3.3 to + 3.3 mm2; CCC = 0.84, 95‰ CI from 0.80 to 0.88) and PA (mean difference = 2.4±2.4 mm2, 95‰ limits of agreement from -2.3 to + 7.1 mm2; CCC = 0.64, 95‰ CI from 0.58 to 0.71).Conclusion:In thisex vivoexperimental model we demonstrated good agreement between coronary artery morphometrical measurements obtained by high-resolution MRI and by histopathology.

High-Resolution Magnetic Resonance Imaging of the Human Median Nerve

2004 ◽  
Vol 18 (2) ◽  
pp. 80-87 ◽  
Author(s):  
Archie Heddings ◽  
Mehmet Bilgen ◽  
Randolph Nudo ◽  
Bruce Toby ◽  
Terence McIff ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Peripheral Nerve ◽  
Median Nerve ◽  
Ex Vivo ◽  
Imaging Techniques ◽  
Proton Density ◽  
Resonance Imaging ◽  
Imaging Protocols

Objectives. It is widely accepted that peripheral nerve repairs performed within 6 weeks of injury have much better outcomes than those performed at later dates. However, there is no diagnostic technique that can determine if a traumatic peripheral nerve injury requires surgical intervention in the early postinjury phase. The objective of this article was to determine whether novel, noninvasive magnetic resonance imaging techniques could demonstrate the microstructure of human peripheral nerves that is necessary for determining prognosis and determining if surgery is indicated following traumatic injury. Methods. Ex vivo magnetic resonance imaging protocols were developed on a 9.4-T research scanner using spin-echo proton density and gradient-echo imaging sequences and a specially designed, inductively coupled radio frequency coil. These imaging protocols were applied to in situ imaging of the human median nerve in 4 fresh-frozen cadaver arms. Results. Noninvasive high-resolution images of the human median nerve were obtained. Structures in the nerve that were observed included fascicles, interfascicular epineurium, perineurium, and intrafascicular septations. Conclusion. Application of these imaging techniques to clinical scanners could provide physicians with a tool that is capable of grading the severity of nerve injuries and providing indications for surgery in the early postinjury phase.

PD54-08 EX-VIVO EXPERIMENTAL 7 TESLA HIGH RESOLUTION MAGNETIC RESONANCE IMAGING - OF LOCALIZED PROSTATE CANCER

2020 ◽  
Vol 203 ◽  
pp. e1106-e1107
Author(s):  
Matthieu Durand* ◽  
Thomas Bessede ◽  
Patrick-Julien Treacy ◽  
Imad Bentellis ◽  
Idoia Corcuera-Solano ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Ex Vivo ◽  
Localized Prostate Cancer ◽  
7 Tesla ◽  
Resonance Imaging

scholarly journals Ex-vivo experimental 7 Tesla high resolution magnetic resonance imaging of localized prostate cancer

2020 ◽  
Vol 19 ◽  
pp. e585-e586
Author(s):  
M. Durand ◽  
T. Bessede ◽  
P-J. Treacy ◽  
I. Bentellis ◽  
I. Corcuera-Solano ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Ex Vivo ◽  
Localized Prostate Cancer ◽  
7 Tesla ◽  
Resonance Imaging

scholarly journals Presence of Vessel Wall Hyperintensity in Unruptured Arteriovenous Malformations on Vessel Wall Magnetic Resonance Imaging: Pilot Study of AVM Vessel Wall “Enhancement”

2021 ◽  
Vol 15 ◽  
Author(s):  
Laura B. Eisenmenger ◽  
Jacqueline C. Junn ◽  
Daniel Cooke ◽  
Steven Hetts ◽  
Chengcheng Zhu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Pilot Study ◽  
High Risk ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Arteriovenous Malformation ◽  
Arteriovenous Malformations ◽  
Vessel Wall ◽  
Susceptibility Weighted Imaging ◽  
Resonance Imaging

Purpose: High-resolution vessel wall magnetic resonance imaging (VW-MRI) could provide a way to identify high risk arteriovenous malformation (AVM) features. We present the first pilot study of clinically unruptured AVMs evaluated by high-resolution VW-MRI.Methods: A retrospective review of clinically unruptured AVMs with VW-MRI between January 1, 2016 and December 31, 2018 was performed documenting the presence or absence of vessel wall “hyperintensity,” or enhancement, within the nidus as well as perivascular enhancement and evidence of old hemorrhage (EOOH). The extent of nidal vessel wall “hyperintensity” was approximated into five groups: 0, 1–25, 26–50, 51–75, and 76–100%.Results: Of the nine cases, eight demonstrated at least some degree of vessel wall nidus “hyperintensity.” Of those eight cases, four demonstrated greater than 50% of the nidus with hyperintensity at the vessel wall, and three cases had perivascular enhancement adjacent to nidal vessels. Although none of the subjects had prior clinical hemorrhage/AVM rupture, of the six patients with available susceptibility weighted imaging to assess for remote hemorrhage, only two had subtle siderosis to suggest prior sub-clinical bleeds.Conclusion: Vessel wall “enhancement” occurs in AVMs with no prior clinical rupture. Additional studies are needed to further investigate the implication of these findings.

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