scholarly journals Exogenous contrast agent improves sensitivity of gradient-echo functional magnetic resonance imaging at 9.4 T

2004 ◽  
Vol 52 (6) ◽  
pp. 1272-1281 ◽  
Author(s):  
Joseph B. Mandeville ◽  
Bruce G. Jenkins ◽  
Yin-Ching I. Chen ◽  
Ji-Kyung Choi ◽  
Young R. Kim ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Contrast Agent ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Gradient Echo ◽  
Exogenous Contrast Agent

A pH-Sensitive Contrast Agent for Functional Magnetic Resonance Imaging (MRI)

1998 ◽  
Vol 27 (7) ◽  
pp. 693-694 ◽  
Author(s):  
Masahito Mikawa ◽  
Naoto Miwa ◽  
Matthias Bräutigam ◽  
Toshihiro Akaike ◽  
Atsushi Maruyama
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Contrast Agent ◽  
Ph Sensitive ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

Functional Magnetic Resonance Imaging Measures of Blood Flow Patterns in the Human Auditory Cortex in Response to Sound

1998 ◽  
Vol 41 (3) ◽  
pp. 538-548 ◽  
Author(s):  
Sean C. Huckins ◽  
Christopher W. Turner ◽  
Karen A. Doherty ◽  
Michael M. Fonte ◽  
Nikolaus M. Szeverenyi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Blood Flow ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Speech Stimuli ◽  
Complex Stimuli ◽  
Scanning Session ◽  
Auditory Research

Functional Magnetic Resonance Imaging (fMRI) holds exciting potential as a research and clinical tool for exploring the human auditory system. This noninvasive technique allows the measurement of discrete changes in cerebral cortical blood flow in response to sensory stimuli, allowing determination of precise neuroanatomical locations of the underlying brain parenchymal activity. Application of fMRI in auditory research, however, has been limited. One problem is that fMRI utilizing echo-planar imaging technology (EPI) generates intense noise that could potentially affect the results of auditory experiments. Also, issues relating to the reliability of fMRI for listeners with normal hearing need to be resolved before this technique can be used to study listeners with hearing loss. This preliminary study examines the feasibility of using fMRI in auditory research by performing a simple set of experiments to test the reliability of scanning parameters that use a high resolution and high signal-to-noise ratio unlike that presently reported in the literature. We used consonant-vowel (CV) speech stimuli to investigate whether or not we could observe reproducible and consistent changes in cortical blood flow in listeners during a single scanning session, across more than one scanning session, and in more than one listener. In addition, we wanted to determine if there were differences between CV speech and nonspeech complex stimuli across listeners. Our study shows reproducibility within and across listeners for CV speech stimuli. Results were reproducible for CV speech stimuli within fMRI scanning sessions for 5 out of 9 listeners and were reproducible for 6 out of 8 listeners across fMRI scanning sessions. Results of nonspeech complex stimuli across listeners showed activity in 4 out of 9 individuals tested.

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