Brain perfusion territory imaging applying oblique-plane arterial spin labeling with a standard send/receive head coil

2004 ◽  
Vol 52 (6) ◽  
pp. 1443-1447 ◽  
Author(s):  
Richard Werner ◽  
Karsten Alfke ◽  
Tobias Schaeffter ◽  
Arya Nabavi ◽  
H. Maximilian Mehdorn ◽  
...  
Keyword(s):  
Arterial Spin Labeling ◽  
Brain Perfusion ◽  
Spin Labeling ◽  
Head Coil ◽  
Perfusion Territory

Challenges for Non-Invasive Brain Perfusion Quantification Using Arterial Spin Labeling

2011 ◽  
Vol 24 (1) ◽  
pp. 77-83 ◽  
Author(s):  
I. Sousa ◽  
N. Santos ◽  
J. Sanches ◽  
P. Vilela ◽  
P. Figueiredo
Keyword(s):  
Arterial Spin Labeling ◽  
Brain Perfusion ◽  
Spin Labeling ◽  
Non Invasive ◽  
Perfusion Quantification

scholarly journals Effects of Acquisition Parameter Modifications and Field Strength on the Reproducibility of Brain Perfusion Measurements Using Arterial Spin-Labeling

2020 ◽  
Vol 42 (1) ◽  
pp. 109-115
Author(s):  
K.P.A. Baas ◽  
J. Petr ◽  
J.P.A. Kuijer ◽  
A.J. Nederveen ◽  
H.J.M.M. Mutsaerts ◽  
...  
Keyword(s):  
Field Strength ◽  
Arterial Spin Labeling ◽  
Brain Perfusion ◽  
Spin Labeling ◽  
Perfusion Measurements

scholarly journals Dual-Echo Arterial Spin Labeling for Brain Perfusion Quantification and Functional Analysis

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
André Monteiro Paschoal ◽  
Fernando Fernandes Paiva ◽  
Renata Ferranti Leoni
Keyword(s):  
Arterial Spin Labeling ◽  
Pulse Sequence ◽  
Brain Connectivity ◽  
Motor Task ◽  
Brain Perfusion ◽  
Spin Labeling ◽  
Blood Oxygenation ◽  
Specific Response ◽  
Bivariate Correlation ◽  
Dual Echo

Arterial Spin Labeling (ASL) is a noninvasive MRI-based method to measure cerebral blood flow (CBF). Recently, the study of ASL as a functional tool has emerged once CBF fluctuation comes from capillaries in brain tissue, giving a more spatially specific response when compared to the standard functional MRI method, based on the blood oxygenation level-dependent (BOLD) contrast. Although the BOLD effect could be desirable to study brain function, if one aims to quantify CBF, such effect is considered contamination that can be more attenuated if short TE value is used in the image acquisition. An approach that provides both CBF and function information in a simultaneous acquisition is the use of a dual-echo ASL (DE-ASL) readout. Our purpose was to evaluate the information provided by DE-ASL regarding CBF quantification and functional connectivity with a motor task. Pseudocontinuous ASL of twenty healthy subjects (age: 32.4 ± 10.2 years, 13 male) was acquired at a 3T scanner. We analyzed the influence of TE on CBF values and brain connectivity provided by CBF and concurrent BOLD (cc-BOLD) time series. Brain networks were obtained by the general linear model and independent component analysis. Connectivity matrices were generated using a bivariate correlation (Fisher Z values). No effect of the sequence readout, but significant effect of the TE value, was observed on gray matter CBF values. Motor networks with reduced extension and more connections with important regions for brain integration were observed for CBF data acquired with short TE, proving its higher spatial specificity. Therefore, it was possible to use a dual-echo readout provided by a standard commercial ASL pulse sequence to obtain reliable quantitative CBF values and functional information simultaneously.

Diagnostic utility of arterial spin labeling in identifying changes in brain perfusion in patients with carbon monoxide poisoning

2020 ◽  
Vol 64 ◽  
pp. 92-96
Author(s):  
Hakan Cebeci ◽  
Mehmet Sedat Durmaz ◽  
Serdar Arslan ◽  
Abdullah Arslan ◽  
Ali Fuat Tekin ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Arterial Spin Labeling ◽  
Carbon Monoxide Poisoning ◽  
Brain Perfusion ◽  
Spin Labeling ◽  
Diagnostic Utility

scholarly journals Stability of MR brain-perfusion measurement using arterial spin labeling

2015 ◽  
Vol 2 (S1) ◽  
Author(s):  
Jan Petr ◽  
Frank Hofheinz ◽  
Ivan Platzek ◽  
Georg Schramm ◽  
Jorg Van Den Hoff
Keyword(s):  
Arterial Spin Labeling ◽  
Brain Perfusion ◽  
Spin Labeling ◽  
Perfusion Measurement ◽  
Mr Brain

scholarly journals Comparison of cerebral blood flow measurement with [15O]-water positron emission tomography and arterial spin labeling magnetic resonance imaging: A systematic review

2016 ◽  
Vol 36 (5) ◽  
pp. 842-861 ◽  
Author(s):  
Audrey P Fan ◽  
Hesamoddin Jahanian ◽  
Samantha J Holdsworth ◽  
Greg Zaharchuk
Keyword(s):  
Positron Emission Tomography ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Brain Perfusion ◽  
Spin Labeling ◽  
Emission Tomography ◽  
Flow Measurements ◽  
Arterial Blood ◽  
Positron Emission

Noninvasive imaging of cerebral blood flow provides critical information to understand normal brain physiology as well as to identify and manage patients with neurological disorders. To date, the reference standard for cerebral blood flow measurements is considered to be positron emission tomography using injection of the [15O]-water radiotracer. Although [15O]-water has been used to study brain perfusion under normal and pathological conditions, it is not widely used in clinical settings due to the need for an on-site cyclotron, the invasive nature of arterial blood sampling, and experimental complexity. As an alternative, arterial spin labeling is a promising magnetic resonance imaging technique that magnetically labels arterial blood as it flows into the brain to map cerebral blood flow. As arterial spin labeling becomes more widely adopted in research and clinical settings, efforts have sought to standardize the method and validate its cerebral blood flow values against positron emission tomography-based cerebral blood flow measurements. The purpose of this work is to critically review studies that performed both [15O]-water positron emission tomography and arterial spin labeling to measure brain perfusion, with the aim of better understanding the accuracy and reproducibility of arterial spin labeling relative to the positron emission tomography reference standard.

scholarly journals Acute Effects of Alcohol on Brain Perfusion Monitored with Arterial Spin Labeling Magnetic Resonance Imaging in Young Adults

2014 ◽  
Vol 34 (3) ◽  
pp. 472-479 ◽  
Author(s):  
Michael Marxen ◽  
Gabriela Gan ◽  
Daniel Schwarz ◽  
Eva Mennigen ◽  
Maximilian Pilhatsch ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Young Adults ◽  
Magnetic Resonance ◽  
Arterial Spin Labeling ◽  
Time Course ◽  
Regional Distribution ◽  
Brain Perfusion ◽  
Spin Labeling ◽  
Acute Tolerance ◽  
Resonance Imaging

While a number of studies have established that moderate doses of alcohol increase brain perfusion, the time course of such an increase as a function of breath alcohol concentration (BrAC) has not yet been investigated, and studies differ about regional effects. Using arterial spin labeling (ASL) magnetic resonance imaging, we investigated (1) the time course of the perfusion increase during a 15-minute linear increase of BrAC up to 0.6 g/kg followed by a steady exposure of 100 minutes, (2) the regional distribution, (3) a potential gender effect, and (4) the temporal stability of perfusion effects. In 48 young adults who participated in the Dresden longitudinal study on alcohol effects in young adults, we observed (1) a 7% increase of global perfusion as compared with placebo and that perfusion and BrAC are tightly coupled in time, (2) that the increase reaches significance in most regions of the brain, (3) that the effect is stronger in women than in men, and (4) that an acute tolerance effect is not observable on the time scale of 2 hours. Larger studies are needed to investigate the origin and the consequences of the effect, as well as the correlates of inter-subject variations.

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