Continuous assessment of perfusion by tagging including volume and water extraction (CAPTIVE): A steady-state contrast agent technique for measuring blood flow, relative blood volume fraction, and the water extraction fraction

1998 ◽  
Vol 40 (5) ◽  
pp. 666-678 ◽  
Author(s):  
Greg Zaharchuk ◽  
Alexei A. Bogdanov ◽  
John J. A. Marota ◽  
Masao Shimizu-Sasamata ◽  
Robert M. Weisskoff ◽  
...  
Keyword(s):  
Blood Flow ◽  
Steady State ◽  
Contrast Agent ◽  
Blood Volume ◽  
Volume Fraction ◽  
Water Extraction ◽  
Continuous Assessment ◽  
Extraction Fraction ◽  
Relative Blood Volume

Continuous assessment of relative cerebral blood volume in transient ischemia using steady state susceptibility-contrast MRI

1996 ◽  
Vol 35 (2) ◽  
pp. 168-173 ◽  
Author(s):  
Leena M. Hamberg ◽  
Pia Boccalini ◽  
George Stranjalis ◽  
George J. Hunter ◽  
Zhihong Huang ◽  
...  
Keyword(s):  
Steady State ◽  
Blood Volume ◽  
Cerebral Blood Volume ◽  
Continuous Assessment ◽  
Transient Ischemia ◽  
Relative Cerebral Blood Volume ◽  
Susceptibility Contrast

Early evolution of deficits in acute ischemic stroke: Mean transit time, relative blood volume, and relative blood flow

2002 ◽  
Vol 11 (2) ◽  
pp. 66-71 ◽  
Author(s):  
Thanh G. Phan ◽  
John Huston ◽  
Norbert G. Campeau ◽  
Robert D. Brown ◽  
Jimmy R. Fulgham ◽  
...  
Keyword(s):  
Blood Flow ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Blood Volume ◽  
Transit Time ◽  
Mean Transit Time ◽  
Early Evolution ◽  
Relative Blood Volume

scholarly journals Absolute Cerebral Blood Volume and Blood Flow Measurements Based on Synchrotron Radiation Quantitative Computed Tomography

2003 ◽  
Vol 23 (4) ◽  
pp. 499-512 ◽  
Author(s):  
Jean-François Adam ◽  
Hélène Elleaume ◽  
Géraldine Le Duc ◽  
Stéphanie Corde ◽  
Anne-Marie Charvet ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Blood Flow ◽  
Synchrotron Radiation ◽  
Contrast Agent ◽  
Blood Volume ◽  
Cerebral Blood Volume ◽  
Quantitative Computed Tomography ◽  
Contrast Material ◽  
Flow Measurements ◽  
Computed Tomography Images

Synchrotron radiation computed tomography opens new fields by using monochromatic x-ray beams. This technique allows one to measure in vivo absolute contrast-agent concentrations with high accuracy and precision, and absolute cerebral blood volume or flow can be derived from these measurements using tracer kinetic methods. The authors injected an intravenous bolus of an iodinated contrast agent in healthy rats, and acquired computed tomography images to follow the temporal evolution of the contrast material in the blood circulation. The first image acquired before iodine infusion was subtracted from the others to obtain computed tomography slices expressed in absolute iodine concentrations. Cerebral blood volume and cerebral blood flow maps were obtained after correction for partial volume effects. Mean cerebral blood volume and flow values (n = 7) were 2.1 ± 0.38 mL/100 g and 129 ± 18 mL · 100 g–1 · min–1 in the parietal cortex; and 1.92 ± 0.32 mL/100 g and 125 ± 17 mL · 100 g–1 · min–1 in the caudate putamen, respectively. Synchrotron radiation computed tomography has the potential to assess these two brain-perfusion parameters.

Rapid-Steady-State-T1 signal modeling during contrast agent extravasation: Toward tumor blood volume quantification without requiring the arterial input function

2014 ◽  
Vol 73 (3) ◽  
pp. 1005-1014 ◽  
Author(s):  
Michel Sarraf ◽  
Adriana Teodora Perles-Barbacaru ◽  
Marie France Nissou ◽  
Boudewijn van der Sanden ◽  
François Berger ◽  
...  
Keyword(s):  
Steady State ◽  
Contrast Agent ◽  
Blood Volume ◽  
Arterial Input Function ◽  
Input Function ◽  
Signal Modeling
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