Noninvasive determination of regional cerebral blood flow in rats using dynamic imaging with Gd(DTPA)

1991 ◽  
Vol 22 (1) ◽  
pp. 32-46 ◽  
Author(s):  
Markus Rudin ◽  
Andre Sauter
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Dynamic Imaging ◽  
Regional Cerebral Blood

Tc-99m HMPAO/SPECT Determination of Regional Cerebral Blood Flow Changes in Schizophrenics

1990 ◽  
Vol 15 (12) ◽  
pp. 904-907 ◽  
Author(s):  
BELKIS ERBAS ◽  
HAKAN KUMBASAR ◽  
G??NAYDIN ERBENGI ◽  
COSKUN BEKDIK
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood ◽  
Hmpao Spect ◽  
Flow Changes

scholarly journals 107. On the Clinical Application of Kr85 Clearance Technique to the Determination of Regional Cerebral Blood Flow

1965 ◽  
Vol 7 ◽  
pp. 244b-245
Author(s):  
Hajime NAGAI ◽  
Masahiro FURUSE ◽  
Kazuhiko OKAMURA ◽  
Inezo TODA ◽  
Yoshihiko OKA ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Clinical Application ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood ◽  
Clearance Technique

The Determination of Regional Cerebral Blood Flow by Means of Water Labeled with Radioactive Oxygen 15

Radiology ◽  
1969 ◽  
Vol 93 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Michel M. Ter-Pogossian ◽  
John O. Eichling ◽  
David O. Davis ◽  
Michael J. Welch ◽  
Judith M. Metzger
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood

Positron Emission Tomography in the Newborn: Extensive Impairment of Regional Cerebral Blood Flow with Intraventricular Hemorrhage and Hemorrhagic Intracerebral Involvement

PEDIATRICS ◽  
1983 ◽  
Vol 72 (5) ◽  
pp. 589-601 ◽  
Author(s):  
Joseph J. Volpe ◽  
Peter Herscovitch ◽  
Jeffrey M. Perlman ◽  
Marcus E. Raichle
Keyword(s):  
Positron Emission Tomography ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Intraventricular Hemorrhage ◽  
Regional Cerebral Blood Flow ◽  
Emission Tomography ◽  
Regional Cerebral Blood ◽  
Ischemic Lesion ◽  
Positron Emission

Of all patients with intraventricular hemorrhage, those with hemorrhagic intracerebral involvement exhibit the highest rates of mortality and neurologic morbidity and, indeed, account for the vast majority of all neurologic impairment in infants with intraventricular hemorrhage. Insight into the basic nature of the critical cerebral involvement requires determination of regional cerebral blood flow, previously not possible. Positron emission tomography (PET) now provides the capability of measuring regional cerebral blood flow with high resolution and little risk. In this study, we utilized PET in six premature infants (920 to 1,200 g) with major intraventricular hemorrhage and hemorrhagic intracerebral involvement to measure regional cerebral blood flow during the acute period (5 to 17 days of age). Cerebral blood flow was determined after intravenous injection of H2O, labeled with the positron-emitting isotope, 15O (oxygen 15). Findings were similar and dramatic in all six infants. In the area of hemorrhagic intracerebral involvement, little or no cerebral blood flow was detected. However, in addition, surprisingly, a marked two- to fourfold reduction in cerebral blood flow was observed throughout the affected hemisphere, well posterior and lateral to the intracerebral hematoma, including cerebral white matter and, to a lesser extent, frontal, temporal, and parietal cortex. In the one infant studied a second time, ie, at 3 months of age, the extent and severity of the decreased cerebral blood flows in the affected hemisphere were similar to those observed on the study during the neonatal period. At the three autopsies, the affected left hemisphere showed extensive infarction, corroborating the PET scans. These observations, the first demonstration of the use of PET in the determination of regional cerebral blood flow in the newborn, show marked impairments in regional cerebral blood flow in the hemisphere containing an apparently restricted intra cerebralhematoma, indicating that the hemorrhagic intracerebral involvement is only a component of a much larger lesion, ischemic in basic nature, ie, an infarction. This large ischemic lesion explains the poor neurologic outcome in infants with intraventricular hemorrhage and hemorrhagic intracerebral involvement.

scholarly journals Determination of Regional Cerebral Blood Flow by Inhalation of 133-Xenon

1967 ◽  
Vol 20 (1) ◽  
pp. 124-135 ◽  
Author(s):  
WALTER D. OBRIST ◽  
HOWARD K. THOMPSON ◽  
HERSCHEL KING ◽  
HSIOH SHAN WANG
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood
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