scholarly journals Proton high-resolution magic angle spinning NMR analysis of fresh and previously frozen tissue of human prostate

2003 ◽  
Vol 50 (6) ◽  
pp. 1307-1311 ◽  
Author(s):  
Chin-Lee Wu ◽  
Jennifer L. Taylor ◽  
Wenlei He ◽  
Andrea G. Zepeda ◽  
Elkan F. Halpern ◽  
...  
Keyword(s):  
High Resolution ◽  
Magic Angle Spinning ◽  
Human Prostate ◽  
Magic Angle ◽  
Nmr Analysis ◽  
Frozen Tissue ◽  
Angle Spinning

scholarly journals High-resolution magic angle spinning proton NMR analysis of human prostate tissue with slow spinning rates

2003 ◽  
Vol 50 (3) ◽  
pp. 627-632 ◽  
Author(s):  
Jennifer L. Taylor ◽  
Chin-Lee Wu ◽  
David Cory ◽  
R. Gilberto Gonzalez ◽  
Anthony Bielecki ◽  
...  
Keyword(s):  
High Resolution ◽  
Proton Nmr ◽  
Magic Angle Spinning ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Magic Angle ◽  
Nmr Analysis ◽  
Human Prostate Tissue ◽  
Angle Spinning

1H high-resolution magic-angle spinning (HR-MAS) NMR analysis of ligand density on resins using a resin internal standard

2004 ◽  
Vol 380 (4) ◽  
pp. 627-631 ◽  
Author(s):  
Laura H. Lucas ◽  
Matthew A. Cerny ◽  
Yakov M. Koen ◽  
Robert P. Hanzlik ◽  
Cynthia K. Larive
Keyword(s):  
High Resolution ◽  
Internal Standard ◽  
Magic Angle Spinning ◽  
Mas Nmr ◽  
Magic Angle ◽  
Nmr Analysis ◽  
Ligand Density ◽  
Angle Spinning

scholarly journals Gelified Biofluids for High-Resolution Magic Angle Spinning 1H NMR Analysis: The Case of Urine

2017 ◽  
Vol 89 (2) ◽  
pp. 1054-1058 ◽  
Author(s):  
Panteleimon G. Takis ◽  
Leonardo Tenori ◽  
Enrico Ravera ◽  
Claudio Luchinat
Keyword(s):  
High Resolution ◽  
1H Nmr ◽  
Magic Angle Spinning ◽  
Magic Angle ◽  
Nmr Analysis ◽  
Angle Spinning

Complete Protocol for Slow-Spinning High-Resolution Magic-Angle Spinning NMR Analysis of Fragile Tissues

2014 ◽  
Vol 86 (21) ◽  
pp. 10749-10754 ◽  
Author(s):  
Marion André ◽  
Jean-Nicolas Dumez ◽  
Lamya Rezig ◽  
Laetitia Shintu ◽  
Martial Piotto ◽  
...  
Keyword(s):  
High Resolution ◽  
Magic Angle Spinning ◽  
Magic Angle ◽  
Nmr Analysis ◽  
Angle Spinning

Reduction of spinning sidebands in proton NMR of human prostate tissue with slow high-resolution magic angle spinning

2005 ◽  
Vol 54 (1) ◽  
pp. 34-42 ◽  
Author(s):  
Melissa A. Burns ◽  
Jennifer L. Taylor ◽  
Chin-Lee Wu ◽  
Andrea G. Zepeda ◽  
Anthony Bielecki ◽  
...  
Keyword(s):  
High Resolution ◽  
Proton Nmr ◽  
Magic Angle Spinning ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Magic Angle ◽  
Human Prostate Tissue ◽  
Angle Spinning

scholarly journals Evaluation of Tissue Metabolites with High Resolution Magic Angle Spinning MR Spectroscopy Human Prostate Samples after Three-Year Storage at –80 °C

2007 ◽  
Vol 2 ◽  
pp. 117727190700200 ◽  
Author(s):  
Kate W. Jordan ◽  
Wenlei He ◽  
Elkan F. Halpern ◽  
Chin-Lee Wu ◽  
Leo L. Cheng
Keyword(s):  
High Resolution ◽  
Mr Spectroscopy ◽  
Frozen Storage ◽  
Storage Conditions ◽  
Magic Angle Spinning ◽  
Human Prostate ◽  
Magic Angle ◽  
Metabolic Degradation ◽  
Specific Tissue ◽  
Angle Spinning

Accurate interpretation and correlation of tissue spectroscopy with pathological conditions requires disease-specific tissue metabolite databases; however, specimens for research are often kept in frozen storage for various lengths of time. Whether such frozen storage results in alterations to the measured metabolites is a critical but largely unknown issue. In this study, human prostate tissues from specimens that had been stored at –80 °C for 32 months were analyzed with high resolution magic angle spinning (HRMAS) magnetic resonance (MR) spectroscopy, and compared with the initial measurements of the adjacent specimens from the same cases when snap frozen in the operation room and kept frozen for less than 24 hours. Results of the current study indicate that that the storage-induced metabolite alterations are below the limits that tissue MR spectroscopy can discriminate. Furthermore, quantitative pathology evaluations suggest the observed alterations in metabolite profiles measured from the adjacent specimens of the same prostates may be accounted for by tissue pathological heterogeneities and are not a result of storage conditions. Hence, these results indicate that long-term frozen storage of prostate specimens can be quantitatively analyzed by HRMAS MR spectroscopy without concerns regarding significant metabolic degradation or alteration.

High resolution magic angle spinning NMR spectroscopy for metabolic assessment of cancer presence and Gleason score in human prostate needle biopsies

2008 ◽  
Vol 21 (6) ◽  
pp. 435-442 ◽  
Author(s):  
Jack J. A. van Asten ◽  
Vincent Cuijpers ◽  
Christina Hulsbergen-van de Kaa ◽  
Claudia Soede-Huijbregts ◽  
J. Alfred Witjes ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
High Resolution ◽  
Gleason Score ◽  
Magic Angle Spinning ◽  
Human Prostate ◽  
Magic Angle ◽  
Angle Spinning

High Resolution Magic Angle Spinning NMR in Combinatorial Chemistry

2001 ◽  
Vol 4 (4) ◽  
pp. 333-351 ◽  
Author(s):  
G. Lippens ◽  
R. Warrass ◽  
J. Wieruszeski ◽  
P. Rousselot-Pailley ◽  
G. Chessari
Keyword(s):  
High Resolution ◽  
Combinatorial Chemistry ◽  
Magic Angle Spinning ◽  
Magic Angle ◽  
Angle Spinning
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