Proton electron double resonance imaging of the in vivo distribution and clearance of a triaryl methyl radical in mice

2002 ◽  
Vol 48 (3) ◽  
pp. 530-534 ◽  
Author(s):  
Haihong Li ◽  
Yuanmu Deng ◽  
Guanglong He ◽  
Periannan Kuppusamy ◽  
David J. Lurie ◽  
...  
2011 ◽  
Vol 35 (2) ◽  
pp. 471-475 ◽  
Author(s):  
Ziqi Sun ◽  
Haihong Li ◽  
Sergey Petryakov ◽  
Alex Samouilov ◽  
Jay L. Zweier

2018 ◽  
Vol 28 (15) ◽  
pp. 1345-1364 ◽  
Author(s):  
Shun Kishimoto ◽  
Murali C. Krishna ◽  
Valery V. Khramtsov ◽  
Hideo Utsumi ◽  
David J. Lurie

2006 ◽  
Vol 55 (3) ◽  
pp. 669-675 ◽  
Author(s):  
Haihong Li ◽  
Guanglong He ◽  
Yuanmu Deng ◽  
Periannan Kuppusamy ◽  
Jay L. Zweier

2014 ◽  
Vol 86 (2) ◽  
pp. 1045-1052 ◽  
Author(s):  
Alexandre Samouilov ◽  
Olga V. Efimova ◽  
Andrey A. Bobko ◽  
Ziqi Sun ◽  
Sergey Petryakov ◽  
...  

A new technique called proton—electron double-resonance imaging is described for imaging free radicals in aqueous samples. The method is a combination of proton NMR imaging with nuclear electron double resonance. The results of using this technique to image free radicals in vivo in the rat are presented. Rats were injected intravenously with a nitroxide free radical solution and a series of images was obtained from which the clearance of the free radical through the liver and kidneys could be observed.


2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S692-S692
Author(s):  
Mathias Hoehn ◽  
Uwe Himmelreich ◽  
Ralph Weber ◽  
Pedro Ramos-Cabrer ◽  
Susanne Wegener ◽  
...  

1974 ◽  
Vol 13 (03) ◽  
pp. 252-257 ◽  
Author(s):  
K. Rörvik - Schümichen ◽  
G. Hoffmann ◽  
C. Schümichen

SummaryAt least two different 99mTc-Sn-pyrophosphate complexes are formed, as it is shown by comparative in vivo distribution studies: A 2 : 2 Sn : pyrophosphate complex is predominant at higher concentrations. Only this complex shows bone seeking properties. A 2 : 1 Sn : pyrophosphate complex exists only at low concentrations. This complex shows no deposition in bone but in the kidneys. Which complex is predominant depends on the pyrophosphate concentration in the equilibrium. Both complexes are rapidly excreted by the kidneys.


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