Bulk magnetic susceptibility effects on the assessment of intra- and extramyocellular lipids in vivo

2002 ◽  
Vol 47 (3) ◽  
pp. 607-610 ◽  
Author(s):  
Lidia S. Szczepaniak ◽  
Robert L. Dobbins ◽  
Daniel T. Stein ◽  
J. Denis McGarry
Keyword(s):  
Magnetic Susceptibility ◽  
Susceptibility Effects ◽  
Bulk Magnetic Susceptibility

scholarly journals Magnetic susceptibility imaging of human habenula at 3 T

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Seulki Yoo ◽  
Joo-won Kim ◽  
John F. Schenck ◽  
Seung-Kyun Lee
Keyword(s):  
Magnetic Susceptibility ◽  
High Resolution ◽  
Transverse Relaxation Rate ◽  
Transverse Relaxation ◽  
Reward Circuitry ◽  
High Prevalence ◽  
Psychiatric Conditions ◽  
Susceptibility Contrast ◽  
Deep Brain

Abstract The habenula plays an important role in brain reward circuitry and psychiatric conditions. While much work has been done on the function and structure of the habenula in animal models, in vivo imaging studies of the human habenula have been relatively scarce due to its small size, deep brain location, and lack of clear biomarkers for its heterogeneous substructure. In this paper, we report high-resolution (0.5 × 0.5 × 0.8 mm3) MRI of the human habenula with quantitative susceptibility mapping (QSM) at 3 T. By analyzing 48 scan datasets collected from 21 healthy subjects, we found that magnetic susceptibility contrast is highly non-uniform within the habenula and across the subjects. In particular, we observed high prevalence of elevated susceptibility in the posterior subregion of the habenula. Correlation analysis between the susceptibility and the effective transverse relaxation rate (R2*) indicated that localized susceptibility enhancement in the habenula is more associated with increased paramagnetic (such as iron) rather than decreased diamagnetic (such as myelin) sources. Our results suggest that high-resolution QSM could make a potentially useful tool for substructure-resolved in vivo habenula imaging, and provide a groundwork for the future development of magnetic susceptibility as a quantitative biomarker for human habenula studies.

Dynamic and magnetic susceptibility effects on the MAS NMR linewidth of a tetrapeptide bound to different resins

2002 ◽  
Vol 40 (2) ◽  
pp. 123-132 ◽  
Author(s):  
Julien Furrer ◽  
Karim Elbayed ◽  
Maryse Bourdonneau ◽  
J�sus Raya ◽  
David Limal ◽  
...  
Keyword(s):  
Magnetic Susceptibility ◽  
Mas Nmr ◽  
Susceptibility Effects

scholarly journals In Vivo Atherosclerotic Plaque Characterization Using Magnetic Susceptibility Distinguishes Symptom-Producing Plaques

2008 ◽  
Vol 1 (1) ◽  
pp. 49-57 ◽  
Author(s):  
Subha V. Raman ◽  
Marshall W. Winner ◽  
Tam Tran ◽  
Murugesan Velayutham ◽  
Orlando P. Simonetti ◽  
...  
Keyword(s):  
Magnetic Susceptibility ◽  
Atherosclerotic Plaque ◽  
Plaque Characterization
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