A Novel ABC Triblock Copolymer with Very Low Surface Energy: Poly(dimethylsiloxane)-block-Poly(methyl methacrylate)-block-Poly(2,2,3,3,4,4,4-heptafluorobutyl methacrylate)

2008 ◽  
Vol 2 (5) ◽  
pp. 398-406 ◽  
Author(s):  
Zhenghong Luo ◽  
Tengyun He ◽  
Haijiang Yu ◽  
Lizong Dai
Keyword(s):  
Surface Energy ◽  
Methyl Methacrylate ◽  
Triblock Copolymer ◽  
Poly Methyl Methacrylate ◽  
Low Surface Energy ◽  
Abc Triblock Copolymer

Surface-energy characteristics of films of molecular brushes based on polyimide and poly(methyl methacrylate)

2016 ◽  
Vol 58 (3) ◽  
pp. 336-344 ◽  
Author(s):  
A. E. Chalykh ◽  
V. Yu. Stepanenko ◽  
N. Yu. Budylin ◽  
A. A. Shcherbina ◽  
I. V. Ivanov ◽  
...  
Keyword(s):  
Surface Energy ◽  
Methyl Methacrylate ◽  
Energy Characteristics ◽  
Poly Methyl Methacrylate ◽  
Molecular Brushes

Substrate Surface Energy Dependent Morphology and Dewetting in an ABC Triblock Copolymer Film

Langmuir ◽  
2007 ◽  
Vol 23 (6) ◽  
pp. 3355-3362 ◽  
Author(s):  
Thomas H. Epps ◽  
Dean M. DeLongchamp ◽  
Michael J. Fasolka ◽  
Daniel A. Fischer ◽  
Erin L. Jablonski
Keyword(s):  
Surface Energy ◽  
Triblock Copolymer ◽  
Substrate Surface ◽  
Copolymer Film ◽  
Abc Triblock Copolymer ◽  
Energy Dependent

Decreased Attachment of Bacteria to Lubricin Coated Intraocular Lenses

2011 ◽  
Vol 1316 ◽  
Author(s):  
George E. Aninwene ◽  
Erik Taylor ◽  
Amy Mei ◽  
Gregory D. Jay ◽  
Thomas J. Webster
Keyword(s):  
Staphylococcus Aureus ◽  
Synovial Fluid ◽  
Surface Energy ◽  
Methyl Methacrylate ◽  
Intraocular Lens ◽  
Bacterial Attachment ◽  
Intraocular Lenses ◽  
Poly Methyl Methacrylate ◽  
Bacterial Proliferation

ABSTRACTLubricin is an amphiphilic glycoprotein that is found in the synovial fluid [1]. This protein holds promise as an anti-biofouling agent. This study investigated lubricin’s ability to prevent bacterial attachment and proliferation on intraocular lenses. The findings from this study indicated that lubricin is able to reduce the attachment of Staphylococcus aureus to poly (methyl methacrylate) intraocular lens. Lubricin coatings were confirmed on the surfaces after a 2 hour soak by changes in surface energy. Also, lubricin reduced bacterial proliferation.

scholarly journals Cell Morphology on Poly(methyl methacrylate) Microstructures as Function of Surface Energy

2019 ◽  
Vol 2019 ◽  
pp. 1-12
Author(s):  
Matthias Katschnig ◽  
Boris Maroh ◽  
Natascha Andraschek ◽  
Sandra Schlögl ◽  
Ulrike Zefferer ◽  
...  
Keyword(s):  
Contact Angle ◽  
Cell Adhesion ◽  
Surface Energy ◽  
Methyl Methacrylate ◽  
Cell Elongation ◽  
Cell Phenotype ◽  
Critical Surface ◽  
Poly Methyl Methacrylate ◽  
Angle Measurements ◽  
Contact Angle Measurements

Whilst the significance of substrate topography as a regulator of cell function is well established, a systematic analysis of the principles underlying this is still unavailable. Here we evaluate the hypothesis that surface energy plays a decisive role in substrate-mediated modulation of cell phenotype by evaluation of cell behaviour on synthetic microstructures exhibiting pronounced differences in surface energy. These microstructures, specifically cubes and walls, were fabricated from a biocompatible base polymer, poly(methyl methacrylate), by variotherm injection molding. The dimensions of the cubes were 1 μm x 1 μm x 1 μm (height x width x length) with a periodicity of 1:1 and 1:5 and the dimensions of the walls 1 μm x 1 μm x 15 mm (height x width x length) with a periodicity of 1:1 and 1:5. Mold inserts were made by lithography and electroplating. The surface energy of the resultant microstructures was determined by static contact angle measurements. Light scanning microscopy of the morphology of NT2/D1 and MC3T3-E1 preosteoblast cells cultured on structured PMMA samples in both cases revealed a profound surface energy dependence. “Walls” appeared to promote significant cell elongation, whilst a lack of cell adhesion was observed on “cubes” with the lowest periodicity. Contact angle measurements on walls revealed enhanced surface energy anisotropy (55 mN/m max., 10 mN/m min.) causing a lengthwise spreading of the test liquid droplet, similar to cell elongation. Surface energy measurements for cubes revealed increased isotropic hydrophobicity (87° max., H2O). A critical water contact angle of ≤ 80° appears to be necessary for adequate cell adhesion. A “switch” for cell adhesion and subsequently cell growth could therefore be applied by, for example, adjusting the periodicity of hydrophobic structures. In summary cell elongation on walls and a critical surface energy level for cell adhesion could be produced for NT2/D1 and MC3T3-E1 cells by symmetrical and asymmetrical energy barrier levels. We, furthermore, propose a water-drop model providing a common physicochemical cause regarding similar cell/droplet geometries and cell adhesion on the investigated microstructures.

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