Clinical characteristics and treatment of azoospermia and severe oligospermia patients with Y-chromosome microdeletions

2013 ◽  
Vol 80 (11) ◽  
pp. 908-915 ◽  
Author(s):  
Fengbin Zhang ◽  
Lejun Li ◽  
Liquan Wang ◽  
Liming Yang ◽  
Zhongyan Liang ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Clinical Characteristics ◽  
Y Chromosome Microdeletions

Detection Y Chromosome Microdeletions Among Iraq Population in Infertile Patients with Azoospermia and Severe Oligospermia

2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Samah A Hammood ◽  
Alaauldeen S M AL-Sallami ◽  
Saleh M Al-Khafaji
Keyword(s):  
Y Chromosome ◽  
Karyotype Analysis ◽  
Semen Analysis ◽  
Obstructive Azoospermia ◽  
Severe Oligozoospermia ◽  
Infertile Men ◽  
Y Chromosome Microdeletions ◽  
Detailed Evaluation ◽  
Health Organization ◽  
Infertile Patients

Objective: To detection of microdeletions of Y chromosome and study the frequency of microdeletions in infertile men with non-obstructive azoospermia or severe oligozoospermia(Middle Euphrates center)in Iraq population. Material and methods: 153 males were included in the study, the casesweredivided into groups according to the infertility etiology and semen analysis according to Word health organization, the frequencies and the characteristicsof Y chromosome microdeletions were investigated in groups. Multiplex PCR was applied to detect the microdeletions. Results:Y chromosome microdeletion was detected in 42 (40.7%) of 153 cases ,Microdeletions in azoospermia showed more frequently detected 28 (52.8%), followed by severe oligospermia 14 (28 %),Microdeletions in the AZFc region were the most common 12 (22.64%), followed by AZFb 11(20.75%) and AZFa 5(9.43%) in azoospermia compared to severe oligospermisAZFc 6 (12%) AZFb 4 (8 %) and AZFa 4 (8%). Conclusion: Y chromosome microdeletions were detected quite frequently in certain infertility subgroups. Therefore, detailed evaluation of an infertile man by physical examination, semen analysis, hormonal evaluationsand when required, karyotype analysis may predict the patients for whom Y chromosome microdeletionanalysis is necessary and also prevent cost increases. Recommendation: This study emphasizes that analysis of microdeletions should be carried out for all patients with idiopathic azoospermia and severe oligospermia who are candidates for intracytoplasmic sperm injection

The incidence of Y-chromosome microdeletions in Pakistani infertile men

2011 ◽  
Vol 22 ◽  
pp. S42
Author(s):  
Nosheen Mujtaba ◽  
Mamoona Naz ◽  
Saima Perveen ◽  
Mamoona Yasmin ◽  
Fida Haider ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Infertile Men ◽  
Y Chromosome Microdeletions

Absence of de novo Y-chromosome microdeletions in male children conceived through intracytoplasmic sperm injection

2004 ◽  
Vol 82 (6) ◽  
pp. 1679-1680 ◽  
Author(s):  
Belén Buch ◽  
José Jorge Galán ◽  
Miguel Lara ◽  
Luis Miguel Real ◽  
Manuel Martínez-Moya ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Intracytoplasmic Sperm Injection ◽  
De Novo ◽  
Y Chromosome Microdeletions

scholarly journals Y-chromosome microdeletions are not associated with SHOX haploinsufficiency

2014 ◽  
Vol 29 (5) ◽  
pp. 1113-1114 ◽  
Author(s):  
C. J. Jorgez ◽  
J. W. Weedin ◽  
A. Sahin ◽  
M. Tannour-Louet ◽  
S. Han ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Y Chromosome Microdeletions

scholarly journals Natural Transmission of b2/b3 Subdeletion or Duplication to Expanded Y Chromosome Microdeletions

2018 ◽  
Vol 24 ◽  
pp. 6559-6563 ◽  
Author(s):  
Yuan Pan ◽  
Lei-lei Li ◽  
Yang Yu ◽  
Yu-ting Jiang ◽  
Xiao Yang ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Y Chromosome Microdeletions

scholarly journals A Study of Y Chromosome Microdeletions in Infertile Indian Males

2004 ◽  
Vol 4 (3) ◽  
pp. 179-185 ◽  
Author(s):  
Arundhati S. Athalye ◽  
Prochi F. Madon ◽  
Nandkishor J. Naik ◽  
Dattatray J. Naik ◽  
Smita S. Gavas ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Y Chromosome Microdeletions
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