Proteomic analysis of follicular fluid from women with and without endometriosis: New therapeutic targets and biomarkers

2013 ◽  
Vol 80 (6) ◽  
pp. 441-450 ◽  
Author(s):  
Edson Guimarães Lo Turco ◽  
Fernanda Bertuccez Cordeiro ◽  
Paula Helena de Carvalho Lopes ◽  
Fábio Cesar Gozzo ◽  
Eduardo Jorge Pilau ◽  
...  
Keyword(s):  
Follicular Fluid ◽  
Proteomic Analysis ◽  
Therapeutic Targets ◽  
New Therapeutic Targets

scholarly journals Comparative proteomic analysis of skin fibroblasts of patients with familial Alzheimer's and healthy controls: Searching for new therapeutic targets

2020 ◽  
Vol 16 (S4) ◽  
Author(s):  
Gustavo Lopez‐Toledo ◽  
Maria del Carmen Silva‐Lucero ◽  
Jose Antonio Arias‐Montaño ◽  
Mariaarmen del CCardenas‐Aguayo
Keyword(s):  
Proteomic Analysis ◽  
Therapeutic Targets ◽  
Skin Fibroblasts ◽  
Healthy Controls ◽  
Comparative Proteomic Analysis ◽  
New Therapeutic Targets

Therapeutic Targets for the Treatment of Comorbidities Associated with Epilepsy

2020 ◽  
Vol 13 (2) ◽  
pp. 85-93
Author(s):  
Kinjal Gangar ◽  
Lokesh Kumar Bhatt
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Neurological Disorders ◽  
Therapeutic Targets ◽  
Therapeutic Failure ◽  
Hyperactivity Disorder ◽  
Novel Targets ◽  
New Therapeutic Targets ◽  
Dual Mechanism ◽  
Seizure Suppression

One of the most common neurological disorders, which occurs among 1% of the population worldwide, is epilepsy. Therapeutic failure is common with epilepsy and nearly about 30% of patients fall in this category. Seizure suppression should not be the only goal while treating epilepsy but associated comorbidities, which can further worsen the condition, should also be considered. Treatment of such comorbidities such as depression, anxiety, cognition, attention deficit hyperactivity disorder and, various other disorders which co-exist with epilepsy or are caused due to epilepsy should also be treated. Novel targets or the existing targets are needed to be explored for the dual mechanism which can suppress both the disease and the comorbidity. New therapeutic targets such as IDO, nNOS, PAR1, NF-κb are being explored for their role in epilepsy and various comorbidities. This review explores recent therapeutic targets for the treatment of comorbidities associated with epilepsy.

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