scholarly journals Listen to your dorsal mesentery: Asymmetric gut rotation is driven by the dorsal mesentery and Pitx2

2012 ◽  
Vol 79 (12) ◽  
pp. 815-815
Author(s):  
Natasza A. Kurpios
Keyword(s):  
Dorsal Mesentery

The development of the dorsal mesentery in human embryos and fetuses

2019 ◽  
Vol 92 ◽  
pp. 18-26 ◽  
Author(s):  
Jill P.J.M. Hikspoors ◽  
Nutmethee Kruepunga ◽  
Greet M.C. Mommen ◽  
Jean-Marie P.W.U. Peeters ◽  
Cindy J.M. Hülsman ◽  
...  
Keyword(s):  
Human Embryos ◽  
Human Embryos And Fetuses ◽  
Dorsal Mesentery

Agenesis of the dorsal mesentery without jejunoileal atresia (“apple peel small bowel”)

1975 ◽  
Vol 10 (2) ◽  
pp. 277-279 ◽  
Author(s):  
James D. Hull ◽  
John L. Kiesel ◽  
Warren H. Proudfoot ◽  
Robert P. Belin
Keyword(s):  
Small Bowel ◽  
Apple Peel ◽  
Jejunoileal Atresia ◽  
Dorsal Mesentery

The Relation of the Interrenal Blastema to the Origin of the Somatic Tissues of the Gonad in Frog Tadpoles

Development ◽  
1954 ◽  
Vol 2 (4) ◽  
pp. 275-289
Author(s):  
Enrico Vannini ◽  
Armando Sabbadin
Keyword(s):  
Germ Cells ◽  
Developmental Stages ◽  
Primordial Germ Cells ◽  
Lateral Position ◽  
Medullary Tissue ◽  
Somatic Tissues ◽  
Frog Tadpoles ◽  
Dorsal Mesentery

As long ago as 1941 and 1942 one of us (Vannini) found in a series of developmental stages of frog tadpoles that the somatic components of the medullary tissue of the gonad have their origin in the interrenal blastema, and not, as was then generally supposed, in the mesonephric blastema. In the earliest stages examined at that time the gonad rudiment had the structure of ‘paired genital ridges’, lying at each side of the dorsal mesentery, and were furnished with primordial germ-cells, but were still without medullary tissue. The interrenal blastema occupied a median site in the tadpole's body, ventral to the aorta and dorsal to the two subcardinal veins. The mesonephric blastemata appeared distinctly separate from the interrenal rudiment, because they were situated in a more lateral position, contiguous with the Wolffian ducts. In later stages the medullary tissue (‘medulla’) penetrated within the genital ridges.

Interactions between primordial germ cells play a role in their migration in mouse embryos

Development ◽  
1994 ◽  
Vol 120 (1) ◽  
pp. 135-141 ◽  
Author(s):  
M. Gomperts ◽  
M. Garcia-Castro ◽  
C. Wylie ◽  
J. Heasman
Keyword(s):  
Germ Cells ◽  
Primordial Germ Cells ◽  
Primitive Streak ◽  
Carbohydrate Antigen ◽  
Mature Stage ◽  
Conventional View ◽  
Embryonic Antigen ◽  
Hind Gut ◽  
Extraembryonic Mesoderm ◽  
Dorsal Mesentery

Primordial germ cells (PGCs) are the founder cell population of the gametes which form during the sexually mature stage of the life cycle. In the mouse, they arise early in embryogenesis, first becoming visible in the extraembryonic mesoderm, posterior to the primitive streak, at 7.5 days post coitum (d.p.c.). They subsequently become incorporated into the epithelium of the hind gut, from which they emigrate (9.5 d.p.c.) and move first into the dorsal mesentery (10.5 d.p.c.), and then into the genital ridges that lie on the dorsal body wall (11.5 d.p.c.). We have used confocal microscopy to study PGCs stained with an antibody that reacts with a carbohydrate antigen (Stage-Specific Embryonic Antigen-1, SSEA-1) carried on the PGC surface. This allows the study of the whole PGC surface, at different stages of their migration. The appearance of PGCs in tissue sections has given rise to the conventional view that they migrate as individuals, each arriving in turn at the genital ridge. In this paper, we show that PGCs leave the hind gut independently, but then extend long (up to 40 microns) processes, with which they link up to each other to form extensive networks. During the 10.5-11.5 d.p.c. period, these networks of PGCs aggregate into groups of tightly apposed cells in the genital ridges. As this occurs, their processes are lost, and their appearance suggests they are now non-motile. Furthermore, we find that PGCs taken from the dorsal mesentery at 10.5 d.p.c. perform the same sequence of movements in culture.(ABSTRACT TRUNCATED AT 250 WORDS)

Germ cell migration in toad (Bufo bufo): effect of ventral grafting of embryonic dorsal regions

Development ◽  
1974 ◽  
Vol 31 (1) ◽  
pp. 75-87
Author(s):  
Piero P. Giorgi
Keyword(s):  
Germ Cell ◽  
Germ Cells ◽  
Primordial Germ Cells ◽  
Ventral Side ◽  
Bufo Bufo ◽  
Tail Bud ◽  
Germ Cell Migration ◽  
Endodermal Cells ◽  
Toad Bufo ◽  
Dorsal Mesentery

Bufo bufo embryos were used at the tail-bud stage for the grafting of two different dorsal regions (cephalic and caudal tracts) into the ventral side of the embryo (cf. Fig. 1). Germ cell localization was studied at the beginning of larval life. The results seem to confirm the original finding of Gipouloux (1970) who suggested that in anurans germ cells migrate under the attraction of a substance produced by the dorsal mesodermal tissues. The attractive action of dorsal tissue was confined to the caudal region of the embryo. In operated specimens the migration of germ cells was drastically altered. The genital ridges of host embryos were almost sterile, while numerous germ cells appeared associated with caudal grafts. A considerably smaller number of germ cells was associated with cephalic grafts. About 80% of germ cells associated with caudal grafts were present at the same levels where a well-developed dorsal mesentery was also present. It is suggested that the formation of the dorsal mesentery plays a morphogenetic role in segregating primordial germ cells from other endodermal cells and contributes to their final localization in the genital ridges.

Differentiation of the dorsal mesentery in man

1970 ◽  
Vol 76 (1) ◽  
pp. 56-67 ◽  
Author(s):  
Y. Yokoh
Keyword(s):  
Dorsal Mesentery

Memoirs: On Certain Features in the Development of the Alimentary Canal in Lepidosiren and Protopterus

1910 ◽  
Vol s2-54 (216) ◽  
pp. 483-518
Author(s):  
J. GRAHAM KERR
Keyword(s):  
Main Part ◽  
Alimentary Canal ◽  
Buccal Cavity ◽  
Ventral Side ◽  
Main Mass ◽  
Lower Jaw ◽  
Right Lobe ◽  
Dorsal Mesentery

1. The fore-gut first becomes folded off from the main mass of yolk-cells. 2. The pyloric valve arises by the hind end of the fore-gut being pushed back into the cavity oE the mid-gut. 3. The main mass of yolk-cells becomes gradually "modelled" into a spirally-coiled intestinal rudiment. 4. The main part of the buccal lining is developed in situ from large yolk-cells. 5. The part of the ventral side of the head, on which, are the olfactory rudiments, becomes enclosed in the buccal cavity by the development of the upper lips and by the forward growth of the lower jaw. 6. The olfactory opening becomes divided into anterior and posterior tiares by the apposition and fusion of the intermediate portion of its lips. 7. The thyroid arises as a solid downgrowth from the buccopharyngeal floor, which gradually becomes cut off from behind forwards. 8. The tongue is a primary tongue like that of Urodeles, but without gland-field. 9. The lung arises from a solid mid-ventral rudiment. 10. When the lung becomes bilobed, the (actual) right lobe is for a time small in size as compared with its fellow. 11. Complicated torsional processes take place during the development of the lung. 12. Through the dorsal mesentery becoming partially merged in the splanchnocoele roof, the lungs come to lie outside the splanchnocoele.

Transfer of Primordial Germ-cells in Xenopus laevis

Development ◽  
1961 ◽  
Vol 9 (4) ◽  
pp. 634-641
Author(s):  
A. W. Blackler ◽  
M. Fischberg
Keyword(s):  
Xenopus Laevis ◽  
Germ Cells ◽  
Germ Line ◽  
Primordial Germ Cells ◽  
Dorsal Region ◽  
Blastula Stage ◽  
Early Embryonic Stage ◽  
Sex Cells ◽  
Fertilized Egg ◽  
Dorsal Mesentery

There have been many claims for the segregation of Anuran primordial germcells at an early embryonic stage. Most authors agree that these cells may be distinguished with ease in the most dorsal region of the larval endoderm and, somewhat later in development, at the base of the dorsal mesentery and in the undifferentiated gonad (see review by Johnston, 1951). Bounoure (1934) and Blackler (1958) claim to have traced the origin of the primordial germ-cells as early in development as the late blastula stage and to have recognized cell inclusions that become restricted to the germ line at all stages between the fertilized egg and the late blastula. As pointed out by Everett (1945), some workers in this field of embryological study have firmly denied the existence of primordial germ-cells, while others have been cautious of accepting the principle that these cells give rise to any of the definitive sex-cells (gametes).

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