The use of lanthanide-induced shifts for conformational and structural studies of (R)-MTPA (α-methoxy-α-trifluoromethyl-α-phenylacetic acid) esters. 2—Complexes of the (R)-MTPA esters of 4-tert-butylcyclohexanols with Eu(fod)3

1984 ◽  
Vol 22 (1) ◽  
pp. 24-28 ◽  
Author(s):  
L. Vanhoeck ◽  
J. Bossaerts ◽  
R. A. Dommisse ◽  
J. A. Lepoivre ◽  
F. C. Alderweireldt
Keyword(s):  
Phenylacetic Acid ◽  
Structural Studies ◽  
Lanthanide Induced Shifts ◽  
Acid Esters

Directed Iridium‐Catalyzed Hydrogen Isotope Exchange Reactions of Phenylacetic Acid Esters and Amides

2019 ◽  
Vol 25 (26) ◽  
pp. 6517-6522 ◽  
Author(s):  
Mégane Valero ◽  
Daniel Becker ◽  
Kristof Jess ◽  
Remo Weck ◽  
Jens Atzrodt ◽  
...  
Keyword(s):  
Hydrogen Isotope ◽  
Isotope Exchange ◽  
Phenylacetic Acid ◽  
Exchange Reactions ◽  
Hydrogen Isotope Exchange ◽  
Acid Esters

Stereoselective Synthesis of 3-azabicyclo[3,3,1]Nonan-9α-yl α-(cyclopentyl-1-ene)-α-hydroxy-α-phenylacetate Hydrochloride

2005 ◽  
Vol 2005 (5) ◽  
pp. 322-323 ◽  
Author(s):  
He Liu ◽  
Xiang-Yu Han ◽  
Bo-Hua Zhong ◽  
Ke-Liang Liu
Keyword(s):  
Mandelic Acid ◽  
Phenylacetic Acid ◽  
Stereoselective Synthesis ◽  
Enantiomeric Excess ◽  
Starting Material ◽  
Sterically Hindered ◽  
Acid Esters

The isomers of α-(cyclopentyl-1-ene)-α-hydroxy-α-phenylacetic acid esters derived from 3-azabicyclo[3,3,1]nonan-9α-ol ((R)-1 and (S)-1) were obtained in high enantiomeric excess by effective stereoselective synthesis from the chiral starting material, (S) or (R)-mandelic acid using pivaldehyde as a sterically hindered reagent

Structural studies of PdCl2L2 complexes with fluorinated phosphines, phosphites, and phosphinites as precursors of benzyl bromide carbonylation catalysts, and and X-ray crystal structure of cis-PdCl2[PPh2(OEt)]2

2001 ◽  
Vol 79 (5-6) ◽  
pp. 752-759 ◽  
Author(s):  
Anna M Trzeciak ◽  
Hubert Bartosz-Bechowski ◽  
Zbigniew Ciunik ◽  
Katarzyna Niesyty ◽  
Józef J Ziólkowski
Keyword(s):  
Phenylacetic Acid ◽  
Acid Methyl Ester ◽  
Benzyl Bromide ◽  
Palladium Complexes ◽  
Structural Studies ◽  
Trans Isomers ◽  
X Ray ◽  
Acid Methyl ◽  
Sterically Demanding ◽  
Nmr Methods

PdCl2L2-type complexes with phosphines (L = PPhx(C6F5)3-x (x = 0-3)), phosphites (L = P(OMe)3, P(OPh)3, P(OEt)3), and phosphinites (L = PPh2(OC6F5), PPh2(O-3,5-F2C6H3), PPh2(OEt), PPh2(O-n-Bu), PPh2(O-t-Bu)) were synthesized and characterized by UV-vis and 31P NMR methods. PdCl2L2 complexes with less sterically demanding phosphines (Θ < 140°) exist as cis isomers, which is confirmed by the X-ray structure of cis-PdCl2[PPh2(OEt)]2. These complexes react with CO in the presence of NEt3 forming Pd(CO)xLy (x + y = 4) type carbonyls characterized by IR spectra. All PdCl2L2 complexes studied are active as precursors of benzyl bromide carbonylation catalysts at 40°C and 1 atm CO; however, the activity of the cis isomers is higher than that of the trans isomers. The highest yields of the carbonylation product, phenylacetic acid methyl ester, were obtained using cis-PdCl2[P(OMe)3]2 (92%), cis-PdCl2[P(OPh)3]2 (89%), and cis-PdCl2[PPh2(O-n-Bu)]2 (78%) as catalyst precursors.Key words: palladium complexes, fluorinated phosphines, benzyl bromide carbonylation.

Mono- and bis(aminomethyl)phenylacetic acid esters as short-acting antiarrhythmic agents. 2

1993 ◽  
Vol 36 (17) ◽  
pp. 2494-2498 ◽  
Author(s):  
Robert J. Chorvat ◽  
Lawrence A. Black ◽  
Vasant V. Ranade ◽  
Cynthia Barcelon-Yang ◽  
David M. Stout ◽  
...  
Keyword(s):  
Phenylacetic Acid ◽  
Antiarrhythmic Agents ◽  
Short Acting ◽  
Acid Esters
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