Gonadal dysfunction due to cis-platinum

2006 ◽  
Vol 17 (5-6) ◽  
pp. 409-413 ◽  
Author(s):  
W. H. B. Wallace ◽  
S. M. Shalet ◽  
E. C. Crowne ◽  
P. H. Morris-Jones ◽  
H. R. Gattamaneni ◽  
...  
Keyword(s):  
Gonadal Dysfunction

Update Treatment for Prolactinoma

2018 ◽  
Vol 3 (06) ◽  
Author(s):  
Chávez Hernández María Margarita ◽  
Jiménez Báez María Valeria ◽  
Armijo Medina María Fernanda ◽  
Domínguez Leyva Jorge Miguel ◽  
Góngora Valencia Karen Alejandra ◽  
...  
Keyword(s):  
Dopamine Agonist ◽  
Safety Profile ◽  
Pituitary Tumor ◽  
Common Type ◽  
Treatment Modalities ◽  
First Line ◽  
Agonist Therapy ◽  
Dopamine Agonist Therapy ◽  
Gonadal Dysfunction

Prolactinomas are the most common type of functional pituitary tumor. The present manuscript is an update on the treatment modalities for prolactinomas. Effective hyperprolactinemia treatment is of great importance, due to its potential deleterious effects including infertility, gonadal dysfunction and osteoporosis. Dopamine agonist therapy is the first line of treatment for prolactinomas; recurrence of disease after cessation of the drug may occur in patients. Its safety profile remains high, allowing its use during pregnancy.

scholarly journals Autism Spectrum Disorder in a Girl with aDe NovoX;19 Balanced Translocation

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Marcelo Razera Baruffi ◽  
Deise Helena de Souza ◽  
Rosana Aparecida Bicudo da Silva ◽  
Ester Silveira Ramos ◽  
Danilo Moretti-Ferreira
Keyword(s):  
X Chromosome ◽  
De Novo ◽  
Recurrent Miscarriage ◽  
Chromosomal Rearrangements ◽  
Position Effect ◽  
Autism Spectrum ◽  
Balanced Translocation ◽  
Replication Banding ◽  
Conventional Cytogenetic Analysis ◽  
Gonadal Dysfunction

Balanced X-autosome translocations are rare, and female carriers are a clinically heterogeneous group of patients, with phenotypically normal women, history of recurrent miscarriage, gonadal dysfunction, X-linked disorders or congenital abnormalities, and/or developmental delay. We investigated a patient with ade novoX;19 translocation. The six-year-old girl has been evaluated due to hyperactivity, social interaction impairment, stereotypic and repetitive use of language with echolalia, failure to follow parents/caretakers orders, inconsolable outbursts, and persistent preoccupation with parts of objects. The girl has normal cognitive function. Her measurements are within normal range, and no other abnormalities were found during physical, neurological, or dysmorphological examinations. Conventional cytogenetic analysis showed ade novobalanced translocation, with the karyotype 46,X,t(X;19)(p21.2;q13.4). Replication banding showed a clear preference for inactivation of the normal X chromosome. The translocation was confirmed by FISH and Spectral Karyotyping (SKY). Although abnormal phenotypes associated withde novobalanced chromosomal rearrangements may be the result of disruption of a gene at one of the breakpoints, submicroscopic deletion or duplication, or a position effect, X; autosomal translocations are associated with additional unique risk factors including X-linked disorders, functional autosomal monosomy, or functional X chromosome disomy resulting from the complex X-inactivation process.

Testicular Defect: The Primary Abnormality in Gonadal Dysfunction of Uremia

1987 ◽  
Vol 80 (6) ◽  
pp. 698-701 ◽  
Author(s):  
GERMAN RAMIREZ ◽  
DORIS BUTCHER ◽  
CARL D. BRUEGGEMEYER ◽  
ARUNHABA GANGULY
Keyword(s):  
Gonadal Dysfunction

scholarly journals PP-02 GONADAL DYSFUNCTION IN ADOLESCENT AND ADULT WOMEN WITH HODGKIN'S DISEASE PRIOR TO TREATMENT

2010 ◽  
Vol 20 ◽  
pp. S51
Author(s):  
Raffaella Fabbri ◽  
Gianandrea Pasquinelli ◽  
Declan Keane ◽  
Valentina Magnani ◽  
Roberto Paradisi ◽  
...  
Keyword(s):  
Hodgkin's Disease ◽  
Hodgkin’S Disease ◽  
Adult Women ◽  
Gonadal Dysfunction

HP-09-002 Gonadal dysfunction in men with chronic kidney disease undergoning hemodialysis

2016 ◽  
Vol 13 (5) ◽  
pp. S139-S140
Author(s):  
N. Ati ◽  
Z. Elati ◽  
R. Sofiene ◽  
A. Mnasser ◽  
W. Zakhama ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Gonadal Dysfunction

Gonadal dysfunction in chronic kidney disease

2016 ◽  
Vol 18 (1) ◽  
pp. 117-130 ◽  
Author(s):  
Biff F. Palmer ◽  
Deborah J. Clegg
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Gonadal Dysfunction

Male gonadal dysfunction

1974 ◽  
Vol 3 (3) ◽  
pp. 507-531 ◽  
Author(s):  
H.W.G. Baker ◽  
Bryan Hudson
Keyword(s):  
Gonadal Dysfunction

scholarly journals Luteinizing Hormone and Follicle Stimulating Hormone-Releasing Hormone Test in Patients with Hypothalamic Pituitary-Gonadal Dysfunction

BMJ ◽  
1973 ◽  
Vol 4 (5884) ◽  
pp. 73-77 ◽  
Author(s):  
C. H. Mortimer ◽  
G. M. Besser ◽  
A. S. McNeilly ◽  
J. C. Marshall ◽  
P. Harsoulis ◽  
...  
Keyword(s):  
Luteinizing Hormone ◽  
Follicle Stimulating Hormone ◽  
Releasing Hormone ◽  
Gonadal Dysfunction ◽  
Stimulating Hormone

scholarly journals Biochemical criteria for the development mechanisms of various reproduction disorders in dairy cows

2021 ◽  
Vol 22 (11) ◽  
Author(s):  
Inna Ventsova ◽  
VLADIMIR SAFONOV
Keyword(s):  
Oxidative Stress ◽  
Dairy Cows ◽  
Malonic Dialdehyde ◽  
Antioxidant Protection ◽  
Factors Analysis ◽  
Gonadal Dysfunction ◽  
Vitamins E And C ◽  
Endocrine Status ◽  
Nitric Oxide Metabolites ◽  
Uterine Diseases

Abstract. Ventsova I, Safonov V. 2021. Biochemical criteria for the development mechanisms of various reproduction disorders in dairy cows. Biodiversitas 22: 4997-5002. The article presents the evaluation of peroxide, antioxidant, and hormonal conditions of high-producing red-and-white dairy cows in the physiological and pathological course of pregnancy and the postpartum period. The blood concentration of malonic dialdehyde, stable nitric oxide metabolites, S-nitrosothiols, vitamins E and C, carotin, gonadal, corticosteroid, and thyroid hormones, as well as activity of GPx, GR, SOD, catalase, and ceruloplasmin, were estimated to define major disorder-provoking factors. Analysis of the data shows that ketosis-gestosis syndrome during pregnancy, postpartum metritis, and gonadal dysfunction occur mainly because of oxidative stress in the context of unbalanced peroxide responses and antioxidant protection. Levels of malonic dialdehyde compared to healthy animals increased by 42.3%, 75%, 56.6%, respectively, as also enzyme activities of GR by 26%, 68.1%, 30.1% and catalase by 17.3%, 45.1%, and 23.9%, correspondingly. The endocrine status indicators in the animals with ketosis-gestosis syndrome changed as follows: progesterone levels were 29.5% lower in cows, 17?-estradiol and cortisol were 20.8% and 14.7% lower, respectively. In animals with inflammatory uterine diseases and depressing reproductive glands, progesterone level was 2 and 3 times lower than in healthy animals, the content of cortisol was 17.6% and 25.1% lower, and testosterone decreased by 21.4% and 75.1%, respectively.

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