Conformal proton radiation treatment for retroperitoneal neuroblastoma: Introduction of a novel technique

2001 ◽  
Vol 37 (1) ◽  
pp. 36-41 ◽  
Author(s):  
Eugen B. Hug ◽  
Meinhard Nevinny-Stickel ◽  
Martin Fuss ◽  
Daniel W. Miller ◽  
Rosemary A. Schaefer ◽  
...  
Keyword(s):  
Radiation Treatment ◽  
Proton Radiation ◽  
Novel Technique

Clinical Applications of Proton Radiation Treatment at Loma Linda University: Review of a Fifteen-year Experience

2006 ◽  
Vol 5 (2) ◽  
pp. 81-89 ◽  
Author(s):  
Jerry D. Slater
Keyword(s):  
Radiation Treatment ◽  
Medical Center ◽  
Clinical Applications ◽  
Proton Radiation ◽  
Photon Irradiation ◽  
Normal Tissues ◽  
Loma Linda University ◽  
Effective Doses ◽  
Radiation Treatments ◽  
Cumulative Experience

Proton radiation therapy has been used at Loma Linda University Medical Center for 15 years, sometimes in combination with photon irradiation, surgery, and chemotherapy, but often as the sole modality. Our initial experience was based on established studies showing the utility of protons for certain management problems, but since then we have engaged in a planned program to exploit the capabilities of proton radiation and expand its applications in accordance with progressively accumulating clinical data. Our cumulative experience has confirmed that protons are a superb tool for delivering conformal radiation treatments, enabling delivery of effective doses of radiation and sparing normal tissues from radiation exposure.

Simulation of organ-specific patient effective dose due to secondary neutrons in proton radiation treatment

2005 ◽  
Vol 50 (18) ◽  
pp. 4337-4353 ◽  
Author(s):  
Hongyu Jiang ◽  
Brian Wang ◽  
X George Xu ◽  
Herman D Suit ◽  
Harald Paganetti
Keyword(s):  
Effective Dose ◽  
Radiation Treatment ◽  
Proton Radiation ◽  
Specific Patient ◽  
Organ Specific ◽  
Secondary Neutrons

scholarly journals Fundus image fusion in EYEPLAN software: An evaluation of a novel technique for ocular melanoma radiation treatment planning

2010 ◽  
Vol 37 (10) ◽  
pp. 5199-5207 ◽  
Author(s):  
Inder K. Daftari ◽  
Kavita K. Mishra ◽  
Joan M. O'Brien ◽  
Tony Tsai ◽  
Susanna S. Park ◽  
...  
Keyword(s):  
Image Fusion ◽  
Treatment Planning ◽  
Radiation Treatment ◽  
Ocular Melanoma ◽  
Fundus Image ◽  
Radiation Treatment Planning ◽  
Novel Technique

scholarly journals Multicomponent T 2 relaxometry reveals early myelin white matter changes induced by proton radiation treatment

2021 ◽  
Author(s):  
Pietro Bontempi ◽  
Daniele Scartoni ◽  
Dante Amelio ◽  
Marco Cianchetti ◽  
Ana Turkaj ◽  
...  
Keyword(s):  
White Matter ◽  
Radiation Treatment ◽  
Proton Radiation ◽  
White Matter Changes

scholarly journals Magnetic resonance imaging detected radiation-induced changes in patients with proton radiation-treated arteriovenous malformations

2021 ◽  
Vol 10 (10) ◽  
pp. 205846012110508
Author(s):  
Maria Correia de Verdier ◽  
Elisabeth Ronne-Engström ◽  
Ljubisa Borota ◽  
Kristina Nilsson ◽  
Erik Blomquist ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Contrast Enhancement ◽  
Arteriovenous Malformations ◽  
Radiation Treatment ◽  
Vasogenic Edema ◽  
Post Treatment ◽  
Proton Radiation ◽  
Radiation Induced ◽  
Mri Changes ◽  
Induced Changes

Background Treatment of intracranial arteriovenous malformations (AVMs) includes surgery, radiation therapy, endovascular occlusion, or a combination. Proton radiation therapy enables very focused radiation, minimizing dose to the surrounding brain. Purpose To evaluate the presence of radiation-induced changes on post-treatment MRI in patients with AVMs treated with proton radiation and to compare these with development of symptoms and nidus obliteration. Material and Methods Retrospective review of pre- and post-treatment digital subtraction angiography and MRI and medical records in 30 patients with AVMs treated with proton radiation. Patients were treated with two or five fractions; total radiation dose was 20–35 physical Gy. Vasogenic edema (minimal, perinidal, or severe), contrast enhancement (minimal or annular), cavitation and nidus obliteration (total, partial, or none) were assessed. Results 26 of 30 patients (87%) developed MRI changes. Vasogenic edema was seen in 25 of 30 (83%), abnormal contrast enhancement in 18 of 26 (69%) and cavitation in 5 of 30 (17%). Time from treatment to appearance of MRI changes varied between 5 and 25 months (median 7, mean 10). Seven patients developed new or deteriorating symptoms that required treatment with corticosteroids; all these patients had extensive MRI changes (severe vasogenic edema and annular contrast enhancement). Not all patients with extensive MRI changes developed symptoms. We found no relation between MRI changes and nidus obliteration. Conclusion Radiation-induced MRI changes are seen in a majority of patients after proton radiation treatment of AVMs. Extensive MRI changes are associated with new or deteriorating symptoms.

DESIGN AND KINEMATIC ANALYSIS OF A ROBOTIZED CHAIR FOR PROTON ADIATION THERAPY

2020 ◽  
Author(s):  
Aleksey Nikolaevich Chernykh
Keyword(s):  
Radiation Therapy ◽  
Head And Neck ◽  
Proton Beam ◽  
Kinematic Analysis ◽  
Radiation Treatment ◽  
Malignant Neoplasms ◽  
Proton Radiation ◽  
Proton Radiotherapy ◽  
Proton Radiation Therapy ◽  
Head Fixation

Proton radiotherapy becomes increasingly important in external radiotherapy. In particular, proton beam radiation therapy is the most successful and almost non-alternative method of radiation treatment of patients with intraocular malignant neoplasms. However, currently, the chairs for positioning patients during proton radiation therapy in the treatment rooms using the fixed proton beam direction do not have the functions of positioning the fixed head and neck. This article presents a new design of a chair for proton radiation therapy with a head and neck positioning device, which is being developed as part of the creation of a research complex for proton radiation therapy of patients with ophthalmic oncology based on the cyclotron C80 at the NRC “Kurchatov Institute” – PNPI. The proposed design of the robotic therapeutic chair is based on the theory of U-TRIZ and ergonomics requirements. The main components of the chair are the mechanism for adjusting the patient position and the device for head fixation device. According to design results, the following analyzes were carried out: weight pressure analysis in order to identify the chair parts, that do not support the required weight, and kinematic analysis for the mechanism that adjusts the chair position. Proposed structure of chair for proton radiotherapy meets requirements for correction of posture and performs function of head and neck positioning.

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