Anatomically aided PET image reconstruction using deep neural networks

2021 ◽  
Author(s):  
Zhaoheng Xie ◽  
Tiantian Li ◽  
Xuezhu Zhang ◽  
Wenyuan Qi ◽  
Evren Asma ◽  
...  
Proceedings ◽  
2019 ◽  
Vol 21 (1) ◽  
pp. 45 ◽  
Author(s):  
Álvaro Hervella ◽  
José Rouco ◽  
Jorge Novo ◽  
Marcos Ortega

This work explores the use of paired and unpaired data for training deep neural networks in the multimodal reconstruction of retinal images. Particularly, we focus on the reconstruction of fluorescein angiography from retinography, which are two complementary representations of the eye fundus. The performed experiments allow to compare the paired and unpaired alternatives.


Author(s):  
Luis Oala ◽  
Cosmas Heiß ◽  
Jan Macdonald ◽  
Maximilian März ◽  
Gitta Kutyniok ◽  
...  

Abstract Purpose The quantitative detection of failure modes is important for making deep neural networks reliable and usable at scale. We consider three examples for common failure modes in image reconstruction and demonstrate the potential of uncertainty quantification as a fine-grained alarm system. Methods We propose a deterministic, modular and lightweight approach called Interval Neural Network (INN) that produces fast and easy to interpret uncertainty scores for deep neural networks. Importantly, INNs can be constructed post hoc for already trained prediction networks. We compare it against state-of-the-art baseline methods (MCDrop, ProbOut). Results We demonstrate on controlled, synthetic inverse problems the capacity of INNs to capture uncertainty due to noise as well as directional error information. On a real-world inverse problem with human CT scans, we can show that INNs produce uncertainty scores which improve the detection of all considered failure modes compared to the baseline methods. Conclusion Interval Neural Networks offer a promising tool to expose weaknesses of deep image reconstruction models and ultimately make them more reliable. The fact that they can be applied post hoc to equip already trained deep neural network models with uncertainty scores makes them particularly interesting for deployment.


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