In‐vivo evaluation of angulated needle‐guide template for MRI‐guided transperineal prostate biopsy

2021 ◽  
Author(s):  
Pedro Moreira ◽  
John Grimble ◽  
Nicusor Iftimia ◽  
Camden P Bay ◽  
Kemal Tuncali ◽  
...  
Keyword(s):  
Prostate Biopsy ◽  
In Vivo Evaluation ◽  
Transperineal Prostate Biopsy ◽  
Mri Guided

MRI-Guided Transperineal Prostate Biopsy Using Commercially Available Prostate Biopsy Planning Systems

Brachytherapy ◽  
2017 ◽  
Vol 16 (3) ◽  
pp. S67
Author(s):  
R. Alex Hsi ◽  
Keith Schulze ◽  
Scott Bildsten ◽  
Carleen T. Bensen ◽  
Aaron Sabolch ◽  
...  
Keyword(s):  
Prostate Biopsy ◽  
Planning Systems ◽  
Transperineal Prostate Biopsy ◽  
Mri Guided

scholarly journals MRI-Guided, Transperineal Prostate Biopsy Using Fixed Coordinate Needle Guide: Initial Feasibility Study

2019 ◽  
Author(s):  
Pankaj Kulkarni ◽  
Sumit Laha ◽  
Sakura Sikander ◽  
Pradipta Biswas ◽  
Heather Cornnell ◽  
...  
Keyword(s):  
Image Registration ◽  
Prostate Biopsy ◽  
Clinical Applications ◽  
Proof Of Concept ◽  
Procedure Time ◽  
3T Mri ◽  
Transperineal Prostate Biopsy ◽  
Guide System ◽  
Mri Guided ◽  
Initial Results

Most of the existing MRI guided robotic needle guide systems have been limited to research purposes and have not progressed towards clinical applications due to complex and bulky structures. The ‘device-to-image’ registration step further complicates the operation and significantly increases the overall procedure time. To address limitations, we developed an MRI guided transperineal prostate biopsy guide system that uses the concept of a ‘fixed coordinate device’ to simplify the overall biopsy procedure and eliminate the registration step, making the procedure more clinically friendly. We performed proof-of-concept targeting experiments using an agar phantom under 3T MRI. The targeting results were analyzed, and initial results prove that the simplified intervention concept would well be feasible. We plan to extend the study further to identify error components.

Development of a Device-to-Image Registration Free Needle Guide for Magnetic Resonance Imaging-Guided Targeted Prostate Biopsy

2020 ◽  
Vol 14 (4) ◽  
Author(s):  
Pankaj Kulkarni ◽  
Sakura Sikander ◽  
Pradipta Biswas ◽  
Sumit Laha ◽  
Heather Cornnell ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Image Registration ◽  
Prostate Biopsy ◽  
Signal To Noise Ratio ◽  
Clinical Environment ◽  
Resonance Imaging ◽  
Transperineal Prostate Biopsy ◽  
Mri Guided ◽  
Magnetic Resonance Imaging Mri

Abstract Significant research has been done in the past decade for the development of magnetic resonance imaging (MRI) guided needle guide (NG) systems for prostate intervention. Most of these systems have been restricted to application in the lab environment with lack of progress toward clinical application. Bulky and complex designs can be attributed to this practice. These systems also demand complex technical setup and usage procedures, which require extra technical personnel during the intervention in addition to specialized training for physicians. Moreover, “device-to-image” registration, essential for accurate and precise targeting, further complicates the overall process while increasing total time for intervention. In order to address these limitations, a simplified, MRI-guided, transperineal prostate biopsy NG system was designed and developed for rapid adoption into the clinical environment. The system consists of a NG device and a software toolkit. It does not require any special intraprocedural technical expertise or dedicated training. Also, to simplify and shorten total procedure time, the device uses the unique concept of “fixed coordinate device” eliminating the need for any device-to-image registration making it clinically friendly. To verify the NG design along with the registration free feature, image quality tests and agar phantom-based targeting experiments were performed under the guidance of 3T MRI scanner. The imaging tests resulted in a distortion of less than 1% in presence of the device and an average change of 1.3% in signal-to-noise ratio. For targeting experiments, maximum in-plane error distance of 3.8 mm with a mean of 2.2 mm and standard deviation of 0.8 mm was observed. The results show that an MRI-compatible simplified intervention device without the need of device-to-image registration is technically feasible.

scholarly journals In-bore setup and software for 3T MRI-guided transperineal prostate biopsy

2012 ◽  
Vol 57 (18) ◽  
pp. 5823-5840 ◽  
Author(s):  
Junichi Tokuda ◽  
Kemal Tuncali ◽  
Iulian Iordachita ◽  
Sang-Eun Song ◽  
Andriy Fedorov ◽  
...  
Keyword(s):  
Prostate Biopsy ◽  
3T Mri ◽  
Transperineal Prostate Biopsy ◽  
Mri Guided

scholarly journals Multi-slice-to-volume registration for MRI-guided transperineal prostate biopsy

2014 ◽  
Vol 10 (5) ◽  
pp. 563-572 ◽  
Author(s):  
Helen Xu ◽  
Andras Lasso ◽  
Andriy Fedorov ◽  
Kemal Tuncali ◽  
Clare Tempany ◽  
...  
Keyword(s):  
Prostate Biopsy ◽  
Transperineal Prostate Biopsy ◽  
Volume Registration ◽  
Mri Guided

scholarly journals Image registration for targeted MRI-guided transperineal prostate biopsy

2012 ◽  
Vol 36 (4) ◽  
pp. 987-992 ◽  
Author(s):  
Andriy Fedorov ◽  
Kemal Tuncali ◽  
Fiona M. Fennessy ◽  
Junichi Tokuda ◽  
Nobuhiko Hata ◽  
...  
Keyword(s):  
Image Registration ◽  
Prostate Biopsy ◽  
Transperineal Prostate Biopsy ◽  
Mri Guided ◽  
Targeted Mri

scholarly journals System Integration and Preliminary Clinical Evaluation of a Robotic System for MRI-Guided Transperineal Prostate Biopsy

2019 ◽  
Vol 04 (02) ◽  
pp. 1950001 ◽  
Author(s):  
Niravkumar A. Patel ◽  
Gang Li ◽  
Weijian Shang ◽  
Marek Wartenberg ◽  
Tamas Heffter ◽  
...  
Keyword(s):  
Clinical Study ◽  
Prostate Biopsy ◽  
Modular Design ◽  
Surgical Navigation ◽  
Robotic System ◽  
Clinical Workflow ◽  
Preclinical Evaluation ◽  
Transperineal Prostate Biopsy ◽  
Patient Consent ◽  
Mri Guided

This paper presents the development, preclinical evaluation, and preliminary clinical study of a robotic system for targeted transperineal prostate biopsy under direct interventional magnetic resonance imaging (MRI) guidance. The clinically integrated robotic system is developed based on a modular design approach, comprised of surgical navigation application, robot control software, MRI robot controller hardware, and robotic needle placement manipulator. The system provides enabling technologies for MRI-guided procedures. It can be easily transported and setup for supporting the clinical workflow of interventional procedures, and the system is readily extensible and reconfigurable to other clinical applications. Preclinical evaluation of the system is performed with phantom studies in a 3 Tesla MRI scanner, rehearsing the proposed clinical workflow, and demonstrating an in-plane targeting error of 1.5[Formula: see text]mm. The robotic system has been approved by the institutional review board (IRB) for clinical trials. A preliminary clinical study is conducted with the patient consent, demonstrating the targeting errors at two biopsy target sites to be 4.0[Formula: see text]mm and 3.7[Formula: see text]mm, which is sufficient to target a clinically significant tumor foci. First-in-human trials to evaluate the system’s effectiveness and accuracy for MR image-guided prostate biopsy are underway.

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