scholarly journals A unified multi‐activation (UMA) model of cell survival curves over the entire dose range for calculating equivalent doses in stereotactic body radiation therapy (SBRT), high dose rate brachytherapy (HDRB), and stereotactic radiosurgery (SRS)

2021 ◽  
Author(s):  
Shidong Li ◽  
Curtis Miyamoto ◽  
Bin Wang ◽  
Tawfik Giaddui ◽  
Bizhan Micaily ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Cell Survival ◽  
Dose Rate ◽  
Stereotactic Radiosurgery ◽  
Stereotactic Body Radiation Therapy ◽  
Dose Range ◽  
High Dose Rate ◽  
High Dose ◽  
Survival Curves ◽  
Stereotactic Body Radiation

scholarly journals Stereotactic Radiotherapy in the Retreatment of Recurrent Cervical Cancers, Assessment of Toxicity, and Treatment Response

2016 ◽  
Vol 15 (6) ◽  
pp. 759-765 ◽  
Author(s):  
Antonio Pontoriero ◽  
Giuseppe Iatì ◽  
Dario Aiello ◽  
Stefano Pergolizzi
Keyword(s):  
Radiation Therapy ◽  
Dose Rate ◽  
Stereotactic Body Radiation Therapy ◽  
Radiation Therapy Oncology Group ◽  
High Dose Rate ◽  
High Dose ◽  
European Organization ◽  
Recurrent Cervical Cancer ◽  
Cervical Cancers ◽  
Stereotactic Body Radiation

Aim: To evaluate the role of stereotactic body radiation therapy in the retreatment of locally recurrent cervical cancers. Brachytherapy is the main choice to treat gynecologic cancers. Methods: Patients with recurrent cervical cancer, previously submitted to radiotherapy, were treated with stereotactic body radiation therapy using a CyberKnife system (Accuray Incorporated, Sunnyvale, California) with a fiducial tracking system. Results: From August 2011 to October 2014, 5 patients have been treated. Median age was 81 years (range, 70-84 years). Two patients were diagnosed with adenocarcinoma endometrioid and 3 with squamous cell carcinoma. Toxicity was scored according to the Radiation Therapy Oncology Group/European Organization for Research and Treatment of Cancer criteria. After a median follow-up of 12 months (range, 8-34 months), no severe (>grade 3) acute/late genitourinary or low gastrointestinal toxicity was observed. Conclusion: Our preliminary results of stereotactic body radiation therapy “simulating” high dose rate for recurrent cervical cancers confirm a minimal toxicity and an optimal outcome. The stereotactic body radiation therapy is an alternative to high dose rate brachytherapy for gynecologic tumors.

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