Optimizing Coded Aperture Imaging techniques to allow for online tracking of fiducial markers with high‐energy scattered radiation from treatment beam

2020 ◽  
Vol 47 (9) ◽  
pp. 4428-4438
Author(s):  
Adam Mahl ◽  
Brian Miller ◽  
Moyed Miften ◽  
Bernard L. Jones
1997 ◽  
Vol 487 ◽  
Author(s):  
P. F. Bloser ◽  
T. Narita ◽  
J. E. Grindlay ◽  
K. Shah

AbstractWe describe initial results of our program to develop and test Cd-Zn-Te (CZT) detectors with a pixellated array readout. Our primary interest is in the development of relatively thick CZT detectors for use in astrophysical coded aperture telescopes with response extending over the energy range ∼ 10 – 600 keV. The coded aperture imaging configuration requires only relatively large area pixels (1–3 mm), whereas the desired high energy response requires detector thicknesses of at least 3–5 mm. We have developed a prototype detector employing a 10 × 10 × 5 mm CZT substrate and 4 × 4 pixel (1.5 mm each) readout with gold metal contacts for the pixels and continuous gold contact for the bias on the opposite detector face. This MSM contact configuration was fabricated by RMD and tested at Harvard for uniformity, efficiency and spatial as well as spectral resolution. We have developed an ASIC readout (IDE-VA-1) and analysis system and report results, including ∼ 4% (FWHM) energy resolution at 60 keV. A prototype design for a full imaging detector array is discussed.


2004 ◽  
Author(s):  
Jae Sub Hong ◽  
Santosh V. Vadawale ◽  
Minhua Zhang ◽  
Eric C. Bellm ◽  
Andrew Yousef ◽  
...  

2004 ◽  
Vol 184 (5) ◽  
pp. 409-415 ◽  
Author(s):  
J. Eric Jensen ◽  
Jodi Miller ◽  
Peter C. Williamson ◽  
Richard W J. Neufeld ◽  
Ravi S. Menon ◽  
...  

BackgroundMembrane phospholipid and high-energy abnormalities measured with phosphorus magnetic resonance spectroscopy (31P-MRS) have been reported in patients with schizophrenia in several brain regions.AimsUsing improved imaging techniques, previously inaccessible brain regions were examined in patients with first-episode schizophrenia and healthy volunteers with 4.0 T 31P-MRS.MethodBrain spectra were collected in vivo from 15 patients with first-episode schizophrenia and 15 healthy volunteers from 15 cm3 effective voxels in the thalamus, cerebellum, hippocampus, anterior/posterior cingulate, prefrontal cortex and parieto-occipital cortex.ResultsPeople with first-episode schizophrenia showed increased levels of glycerophosphocholine in the anterior cingulate. Inorganic phosphate, phosphocreatine and adenosine triphosphate concentrations were also increased in the anterior cingulate in this group.ConclusionsThe increased phosphodiester and high-energy phosphate levels in the anterior cingulate of brains of people with first-episode schizophrenia may indicate neural overactivity in this region during the early stages of the illness, resulting in increased excitotoxic neural membrane breakdown.


1980 ◽  
Vol 27 (1) ◽  
pp. 375-380 ◽  
Author(s):  
A. Johansson ◽  
B. L. Beron ◽  
L. Campbell ◽  
R. Eichler ◽  
P. Gorodetsky ◽  
...  
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