Evaluation of a deep learning‐based computer‐aided diagnosis system for distinguishing benign from malignant thyroid nodules in ultrasound images

2020 ◽  
Vol 47 (9) ◽  
pp. 3952-3960 ◽  
Author(s):  
Chao Sun ◽  
Yukang Zhang ◽  
Qing Chang ◽  
Tianjiao Liu ◽  
Shaohang Zhang ◽  
...  
2019 ◽  
Vol 64 (23) ◽  
pp. 235013 ◽  
Author(s):  
Hiroki Tanaka ◽  
Shih-Wei Chiu ◽  
Takanori Watanabe ◽  
Setsuko Kaoku ◽  
Takuhiro Yamaguchi

2019 ◽  
Vol 45 ◽  
pp. S4 ◽  
Author(s):  
Hiroki Tanaka ◽  
Shih-Wei Chiu ◽  
Takanori Watanabe ◽  
Setsuko Kaoku ◽  
Takuhiro Yamaguchi

IEEE Access ◽  
2020 ◽  
Vol 8 ◽  
pp. 53223-53231 ◽  
Author(s):  
Shijie Zhang ◽  
Huarui Du ◽  
Zhuang Jin ◽  
Yaqiong Zhu ◽  
Ying Zhang ◽  
...  

2018 ◽  
Vol 54 (8) ◽  
pp. 659-669 ◽  
Author(s):  
Shintaro SUZUKI ◽  
Xiaoyong ZHANG ◽  
Noriyasu HOMMA ◽  
Kei ICHIJI ◽  
Yumi TAKANE ◽  
...  

2019 ◽  
Vol 9 (4) ◽  
pp. 186-193
Author(s):  
Lei Xu ◽  
Junling Gao ◽  
Quan Wang ◽  
Jichao Yin ◽  
Pengfei Yu ◽  
...  

Background: Computer-aided diagnosis (CAD) systems are being applied to the ultrasonographic diagnosis of malignant thyroid nodules, but it remains controversial whether the systems add any accuracy for radiologists. Objective: To determine the accuracy of CAD systems in diagnosing malignant thyroid nodules. Methods: PubMed, EMBASE, and the Cochrane Library were searched for studies on the diagnostic performance of CAD systems. The diagnostic performance was assessed by pooled sensitivity and specificity, and their accuracy was compared with that of radiologists. The present systematic review was registered in PROSPERO (CRD42019134460). Results: Nineteen studies with 4,781 thyroid nodules were included. Both the classic machine learning- and the deep learning-based CAD system had good performance in diagnosing malignant thyroid nodules (classic machine learning: sensitivity 0.86 [95% CI 0.79–0.92], specificity 0.85 [95% CI 0.77–0.91], diagnostic odds ratio (DOR) 37.41 [95% CI 24.91–56.20]; deep learning: sensitivity 0.89 [95% CI 0.81–0.93], specificity 0.84 [95% CI 0.75–0.90], DOR 40.87 [95% CI 18.13–92.13]). The diagnostic performance of the deep learning-based CAD system was comparable to that of the radiologists (sensitivity 0.87 [95% CI 0.78–0.93] vs. 0.87 [95% CI 0.85–0.89], specificity 0.85 [95% CI 0.76–0.91] vs. 0.87 [95% CI 0.81–0.91], DOR 40.12 [95% CI 15.58–103.33] vs. DOR 44.88 [95% CI 30.71–65.57]). Conclusions: The CAD systems demonstrated good performance in diagnosing malignant thyroid nodules. However, experienced radiologists may still have an advantage over CAD systems during real-time diagnosis.


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