scholarly journals Prediction of transient tumor enlargement using MRI tumor texture after radiosurgery on vestibular schwannoma

2020 ◽  
Vol 47 (4) ◽  
pp. 1692-1701 ◽  
Author(s):  
Patrick P. J. H. Langenhuizen ◽  
Sander H. P. Sebregts ◽  
Svetlana Zinger ◽  
Sieger Leenstra ◽  
Jeroen B. Verheul ◽  
...  
Keyword(s):  
Vestibular Schwannoma ◽  
Tumor Enlargement

Vestibular schwannoma management

1998 ◽  
Vol 89 (6) ◽  
pp. 949-955 ◽  
Author(s):  
Bruce E. Pollock ◽  
L. Dade Lunsford ◽  
Douglas Kondziolka ◽  
Raymond Sekula ◽  
Brian R. Subach ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Surgical Resection ◽  
Vestibular Schwannoma ◽  
Tumor Resection ◽  
Gamma Knife Radiosurgery ◽  
Gross Total Resection ◽  
Total Resection ◽  
Content Type ◽  
Tumor Enlargement ◽  
Fine Print

Object. The indications, operative findings, and outcomes of vestibular schwannoma microsurgery are controversial when it is performed after stereotactic radiosurgery. To address these issues, the authors reviewed the experience at two academic medical centers. Methods. During a 10-year interval, 452 patients with unilateral vestibular schwannomas underwent gamma knife radiosurgery. Thirteen patients (2.9%) underwent delayed microsurgery at a median of 27 months (range 7–72 months) after they had undergone radiosurgery. Six of the 13 patients had undergone one or more microsurgical procedures before they underwent radiosurgery. The indications for surgery were tumor enlargement with stable symptoms in five patients, tumor enlargement with new or increased symptoms in five patients, and increased symptoms without evidence of tumor growth in three patients. Gross-total resection was achieved in seven patients and near-gross-total resection in four patients. The surgery was described as more difficult than that typically performed for schwannoma in eight patients, no different in four patients, and easier in one patient. At the last follow-up evaluation, three patients had normal or near-normal facial function, three patients had moderate facial dysfunction, and seven had facial palsies. Three patients were incapable of caring for themselves, and one patient died of progression of a malignant triton tumor. Conclusions. Failed radiosurgery in cases of vestibular schwannoma was rare. No clear relationship was demonstrated between the use of radiosurgery and the subsequent ease or difficulty of delayed microsurgery. Because some patients have temporary enlargement of their tumor after radiosurgery, the need for surgical resection after radiosurgery should be reviewed with the neurosurgeon who performed the radiosurgery and should be delayed until sustained tumor growth is confirmed. A subtotal tumor resection should be considered for patients who require surgical resection of their tumor after vestibular schwannoma radiosurgery.

Facial neuropathy due to axonal degeneration and microvasculitis following gamma knife surgery for vestibular schwannoma: a histological analysis

2003 ◽  
Vol 99 (5) ◽  
pp. 916-920 ◽  
Author(s):  
Takashi Watanabe ◽  
Nobuhito Saito ◽  
Junko Hirato ◽  
Hidetoshi Shimaguchi ◽  
Hiroya Fujimaki ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Vestibular Schwannoma ◽  
Axonal Degeneration ◽  
Histological Analysis ◽  
Resonance Imaging ◽  
Total Removal ◽  
Content Type ◽  
Tumor Margin ◽  
Radiation Induced ◽  
Tumor Enlargement

✓ Complete facial palsy (House—Brackmann Grade VI) developed in a 63-year-old man with a vestibular schwannoma 25 months after he had undergone two gamma knife surgeries performed 33 months apart and involving a cumulative dose of 24 Gy directed to the tumor margin at the 50% isodose line. Magnetic resonance imaging demonstrated tumor enlargement with central nonenhancement, which initially had been recognized 21 months after the second radiosurgery. Microsurgery was performed to achieve total removal of the tumor. Histological and immunohistochemical examinations of the facial nerve specimen removed from the edge of the tumor revealed a loss of axons, proliferation of Schwann cells, and microvasculitis. In this case, microvasculitis and axonal degeneration were probably the major causes of the radiation-induced facial neuropathy.

Manchester Experience of Bevacizumab (Avastin) for Vestibular Schwannoma in Type II Neurofibromatosis

2012 ◽  
Vol 73 (S 02) ◽  
Author(s):  
A. Bala ◽  
G. Evans ◽  
S. Freeman ◽  
S. Lloyd ◽  
S. Rutherford ◽  
...  
Keyword(s):  
Vestibular Schwannoma ◽  
Type Ii

Developing Intraoperative Cochlear Nerve Monitoring during Vestibular Schwannoma Surgery

2012 ◽  
Vol 73 (S 02) ◽  
Author(s):  
A. Kasbekar ◽  
Y. Tam ◽  
R. Carlyon ◽  
J. Deeks ◽  
N. Donnelly ◽  
...  
Keyword(s):  
Vestibular Schwannoma ◽  
Cochlear Nerve ◽  
Nerve Monitoring
Sign in / Sign up

Export Citation Format

Share Document