Simulation studies of time reversal‐based protoacoustic reconstruction for range and dose verification in proton therapy

2019 ◽  
Vol 46 (8) ◽  
pp. 3649-3662 ◽  
Author(s):  
Yajun Yu ◽  
Zhongxing Li ◽  
Dong Zhang ◽  
Lei Xing ◽  
Hao Peng
Keyword(s):  
Proton Therapy ◽  
Time Reversal ◽  
Simulation Studies ◽  
Dose Verification

scholarly journals Fast MCsquare-Based Independent Dose Verification Platform for Pencil Beam Scanning Proton Therapy

2021 ◽  
Vol 20 ◽  
pp. 153303382110330
Author(s):  
Chunbo Liu ◽  
Meng Wei Ho ◽  
Jiyeon Park ◽  
Wen Chien Hsi ◽  
Xiaoying Liang ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Treatment Plan ◽  
Dose Calculation ◽  
Pencil Beam ◽  
Dose Verification ◽  
Beam Scanning ◽  
Water Phantom ◽  
Pencil Beam Scanning ◽  
The Absolute ◽  
Clinical Cases

Purpose: To commission MCsquare (a multi-cores CPU-based dose calculation engine) for pencil beam scanning (PBS) proton therapy, integrate it into RayStation treatment plan system (TPS) to create a dedicated platform for fast independent dose verification. Method: A MCsquare-based independent dose verification platform (MC2InRS) was developed to realize automatic dose re-calculation for clinical use, including data preparation, dose calculation, 2D/3D gamma analysis. MCsquare was commissioned based on in-air lateral dose profiles, integrated depth dose, and the absolute dose of different beam energies for Proteus®ONE. MC2InRS was validated with measurement data using various targets and depths in a water phantom. This study also investigated 15 clinical cases to demonstrate the feasibility and effectiveness of MC2InRS platform in clinic practice. Results: Between simulation and measurement, the distal range differences at 80% (R80) and 20% (R20) dose levels for each energy were below 0.05 mm, and 0.1 mm, respectively, and the absolute dose differences were below 0.5%. 29 out of 36 QA planes reached a 100% gamma passing rate (GPR) for 2%/2mm criteria, and a minimum of 98.3% gamma was obtained in water phantom between simulation and measurement. For the 15 clinical cases investigated, the average 2D GPR (2%/2mm) was 95.4%, 99.3% for MCsquare vs. measurement, MCsquare vs. TPS, respectively. The average 3D GPR (2%/2mm) was 98.9%, 95.3% for MCsquare vs. TPS in water, and computed tomography (CT), respectively. Conclusion: MC2InRS, a fast, independent dose verification platform, has been developed to perform dose verification with high accuracy and efficiency for Pencil Bream Scanning (PBS). Its potential to be applied in routine clinical practice has also been discussed.

TOPAS Monte Carlo model of MD anderson scanning proton beam for simulation studies in proton therapy

2018 ◽  
Vol 4 (3) ◽  
pp. 037001 ◽  
Author(s):  
J Hartman ◽  
X Zhang ◽  
X R Zhu ◽  
S J Frank ◽  
J J W Lagendijk ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Proton Beam ◽  
Proton Therapy ◽  
Monte Carlo Model ◽  
Simulation Studies ◽  
Md Anderson

TH-C-T-617-03: Implementation of Monte Carlo Dose Verification for Proton Therapy QA

2005 ◽  
Vol 32 (6Part21) ◽  
pp. 2164-2164
Author(s):  
J Fan ◽  
W Luo ◽  
J Li ◽  
E Fourkal ◽  
Z Chen ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Proton Therapy ◽  
Dose Verification

SU-E-T-361: Three Dimensional Dose Verification in Proton Therapy Using EBT2 Film Array

2011 ◽  
Vol 38 (6Part16) ◽  
pp. 3570-3570
Author(s):  
M Yoon ◽  
S Kim ◽  
S Choi ◽  
J Han ◽  
D Hwang ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Three Dimensional ◽  
Dose Verification ◽  
Ebt2 Film

A machine learning framework with anatomical prior for online dose verification using positron emitters and PET in proton therapy

2020 ◽  
Vol 65 (18) ◽  
pp. 185003
Author(s):  
Zongsheng Hu ◽  
Guangyao Li ◽  
Xiaoke Zhang ◽  
Kuangkuang Ye ◽  
Jiade Lu ◽  
...  
Keyword(s):  
Machine Learning ◽  
Proton Therapy ◽  
Dose Verification ◽  
Learning Framework ◽  
Positron Emitters
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