Toward automated and personalized organ dose determination in CT examinations — A comparison of two tissue characterization models for Monte Carlo organ dose calculation with a Therapy Planning System

2019 ◽  
Vol 46 (2) ◽  
pp. 1012-1023
Author(s):  
Hans‐Erik Källman ◽  
Erik Traneus ◽  
Anders Ahnesjö
Keyword(s):  
Monte Carlo ◽  
Tissue Characterization ◽  
Dose Calculation ◽  
Organ Dose ◽  
Planning System ◽  
Therapy Planning ◽  
Dose Determination

scholarly journals Evaluation of a treatment planning system developed for clinical boron neutron capture therapy and validation against an independent Monte Carlo dose calculation system

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Naonori Hu ◽  
Hiroki Tanaka ◽  
Ryo Kakino ◽  
Syuushi Yoshikawa ◽  
Mamoru Miyao ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Treatment Planning ◽  
Neutron Capture ◽  
Gamma Ray ◽  
Dose Calculation ◽  
Planning System ◽  
Treatment Planning System ◽  
Neutron Capture Therapy ◽  
Boron Neutron Capture ◽  
Monte Carlo Dose Calculation

AbstractBoron neutron capture therapy (BNCT) for the treatment of unresectable, locally advanced, and recurrent carcinoma of the head and neck cancer has been approved by the Japanese government for reimbursement under the national health insurance as of June 2020. A new treatment planning system for clinical BNCT has been developed by Sumitomo Heavy Industries, Ltd. (Sumitomo), NeuCure® Dose Engine. To safely implement this system for clinical use, the simulated neutron flux and gamma ray dose rate inside a water phantom was compared against experimental measurements. Furthermore, to validate and verify the new planning system, the dose distribution inside an anthropomorphic head phantom was compared against a BNCT treatment planning system SERA and an in-house developed Monte Carlo dose calculation program. The simulated results closely matched the experimental results, within 5% for the thermal neutron flux and 10% for the gamma ray dose rate. The dose distribution inside the head phantom closely matched with SERA and the in-house developed dose calculation program, within 3% for the tumour and a difference of 0.3 Gyw for the brain.

scholarly journals Moving from organ dose to microdosimetry: contribution of the Monte Carlo simulations

2005 ◽  
Vol 48 (spe2) ◽  
pp. 191-199 ◽  
Author(s):  
Christophe Champion
Keyword(s):  
Monte Carlo ◽  
Cross Sections ◽  
Dose Calculation ◽  
Organ Dose ◽  
Monte Carlo Event ◽  
Monte Carlo Code ◽  
Geometrical Modelling ◽  
Electrons And Positrons ◽  
Wave Methods ◽  
Event Simulations

When living cells are irradiated by charged particles, a wide variety of interactions occurs that leads to a deep modification of the biological material. To understand the fine structure of the microscopic distribution of the energy deposits, Monte Carlo event-by-event simulations are particularly suitable. However, the development of these track structure codes needs accurate interaction cross sections for all the electronic processes: ionization, excitation, Positronium formation (for incident positrons) and even elastic scattering. Under these conditions, we have recently developed a Monte Carlo code for electrons and positrons in water, this latter being commonly used to simulate the biological medium. All the processes are studied in detail via theoretical differential and total cross sections calculated by using partial wave methods. Comparisons with existing theoretical and experimental data show very good agreements. Moreover, this kind of detailed description allows one access to a useful microdosimetry, which can be coupled to a geometrical modelling of the target organ and then provide a detailed dose calculation at the nanometric scale.

Comparison of CCC and ETAR dose calculation algorithms in pituitary adenoma radiation treatment planning; Monte Carlo evaluation

2014 ◽  
Vol 13 (4) ◽  
pp. 447-455 ◽  
Author(s):  
K. Tanha ◽  
S. R. Mahdavi ◽  
G. Geraily
Keyword(s):  
Monte Carlo ◽  
Pituitary Adenoma ◽  
Treatment Planning ◽  
Radiation Treatment ◽  
Dose Calculation ◽  
Planning System ◽  
Treatment Planning System ◽  
Significant Difference ◽  
Calculation Algorithms ◽  
Dose Calculation Algorithms

AbstractAimsTo verify the accuracy of two common absorbed dose calculation algorithms in comparison to Monte Carlo (MC) simulation for the planning of the pituitary adenoma radiation treatment.Materials and methodsAfter validation of Linac's head modelling by MC in water phantom, it was verified in Rando phantom as a heterogeneous medium for pituitary gland irradiation. Then, equivalent tissue-air ratio (ETAR) and collapsed cone convolution (CCC) algorithms were compared for a conventional three small non-coplanar field technique. This technique uses 30 degree physical wedge and 18 MV photon beams.ResultsDose distribution findings showed significant difference between ETAR and CCC of delivered dose in pituitary irradiation. The differences between MC and dose calculation algorithms were 6.40 ± 3.44% for CCC and 10.36 ± 4.37% for ETAR. None of the algorithms could predict actual dose in air cavity areas in comparison to the MC method.ConclusionsDifference between calculation and true dose value affects radiation treatment outcome and normal tissue complication probability. It is of prime concern to select appropriate treatment planning system according to our clinical situation. It is further emphasised that MC can be the method of choice for clinical dose calculation algorithms verification.

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