Chickpea extract ameliorates metabolic syndrome symptoms via restoring intestinal ecology and metabolic profile in type 2 diabetic rats

2021 ◽  
pp. 2100007
Author(s):  
Pei Li ◽  
Biyu Lu ◽  
Jing Gong ◽  
Lin Li ◽  
Guoping Chen ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Metabolic Profile ◽  
Diabetic Rats ◽  
Intestinal Ecology ◽  
Type 2 Diabetic

scholarly journals Tetrapleura tetraptera spice attenuates high-carbohydrate, high-fat diet-induced obese and type 2 diabetic rats with metabolic syndrome features

2015 ◽  
Vol 14 (1) ◽  
Author(s):  
Dieudonne Kuate ◽  
Anne Pascale Nouemsi Kengne ◽  
Cabral Prosper Nya Biapa ◽  
Boris Gabin Kingue Azantsa ◽  
Wan Abdul Manan Bin Wan Muda
Keyword(s):  
Metabolic Syndrome ◽  
High Fat Diet ◽  
Diabetic Rats ◽  
High Fat ◽  
High Carbohydrate ◽  
Tetrapleura Tetraptera ◽  
Type 2 Diabetic

Preventive action of retinoids in metabolic syndrome/type 2 diabetic rats fed with citrus functional food enriched in β-cryptoxanthin

2020 ◽  
Vol 11 (10) ◽  
pp. 9263-9271
Author(s):  
Claudie Dhuique-Mayer ◽  
Laura Gence ◽  
Karine Portet ◽  
Didier Tousch ◽  
Patrick Poucheret
Keyword(s):  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Functional Food ◽  
Diabetic Rats ◽  
Syndrome Type ◽  
Preventive Action ◽  
Type 2 Diabetic

A citrus functionnal food enriched in β-cryptoxanthin to prevent metabolic syndrome/type 2 diabetes.

scholarly journals Exercise and Beta-Glucan Consumption (Saccharomyces cerevisiae) Improve the Metabolic Profile and Reduce the Atherogenic Index in Type 2 Diabetic Rats (HFD/STZ)

Nutrients ◽  
2016 ◽  
Vol 8 (12) ◽  
pp. 792 ◽  
Author(s):  
Eric Andrade ◽  
Andressa Lima ◽  
Ingrid Nunes ◽  
Débora Orlando ◽  
Paula Gondim ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Metabolic Profile ◽  
Diabetic Rats ◽  
Atherogenic Index ◽  
Beta Glucan ◽  
Type 2 Diabetic

Study on the Effect of Cerium Oxide Nanocubes on Full-Thickness Cutaneous Wound Healing of Type 2 Diabetic Rats

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 643-P ◽  
Author(s):  
YANFEI HAN ◽  
LINDONG LI ◽  
YANJUN LIU ◽  
YOU WANG ◽  
CHUNHUA YAN ◽  
...  
Keyword(s):  
Wound Healing ◽  
Cerium Oxide ◽  
Diabetic Rats ◽  
Cutaneous Wound Healing ◽  
Full Thickness ◽  
Cutaneous Wound ◽  
Type 2 Diabetic

Neuroprotection of Maslinic Acid, a Novel Glycogen Phos-phorylase Inhibitor, in Type 2 Diabetic Rats

2010 ◽  
Vol 8 (4) ◽  
pp. 293-297 ◽  
Author(s):  
Teng GUAN ◽  
Yi-Song QIAN ◽  
Meng-Hao HUANG ◽  
Long-Fei HUANG ◽  
Xu-Zhen TANG ◽  
...  
Keyword(s):  
Diabetic Rats ◽  
Maslinic Acid ◽  
Type 2 Diabetic

Blockade of Renin Angiotensin System Ameliorates the Cardiac Arrhythmias and Sympathetic Neural Remodeling in Hearts of Type 2 DM Rat Model

2020 ◽  
Vol 20 (3) ◽  
pp. 464-478 ◽  
Author(s):  
Yomna M. Yehya ◽  
Abdelaziz M. Hussein ◽  
Khaled Ezam ◽  
Elsayed A. Eid ◽  
Eman M. Ibrahim ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiac Arrhythmias ◽  
Sympathetic Nerve ◽  
Renin Angiotensin System ◽  
Diabetic Rats ◽  
Angiotensin System ◽  
Type 2 Dm ◽  
Type 2 Diabetic ◽  
Diabetes Induction

Objectives:: The present study was designed to investigate the effects of renin angiotensin system (RAS) blockade on cardiac arrhythmias and sympathetic nerve remodelling in heart tissues of type 2 diabetic rats. Methods:: Thirty-two male Sprague Dawley rats were randomly allocated into 4 equal groups; a) normal control group: normal rats, b) DM group; after type 2 diabetes induction, rats received 2ml oral saline daily for 4 weeks, c) DM+ ACEi: after type 2 diabetes induction, rats were treated with enalapril (10 mg/kg, orally for 4 weeks) and d) DM+ ARBs: after type 2 diabetes induction, rats were treated with losartan (30 mg/kg, orally for 4 weeks). Results:: In type 2 diabetic rats, the results demonstrated significant prolongation in Q-T interval and elevation of blood sugar, HOMA-IR index, TC, TGs, LDL, serum CK-MB, myocardial damage, myocardial MDA, myocardial norepinephrine and tyrosine hydroxylase (TH) density with significant reduction in serum HDL, serum insulin and myocardial GSH and CAT. On the other hand, blockade of RAS at the level of either ACE by enalapril or angiotensin (Ag) receptors by losartan resulted in significant improvement in ECG parameters (Q-T), cardiac enzymes (CK-MB), cardiac morphology, myocardial oxidative stress (low MDA, high CAT and GSH) and myocardial TH density. Conclusions:: RAS plays a role in the cardiac sympathetic nerve sprouting and cardiac arrhythmias induced by type 2 DM and its blockade might have a cardioprotective effect via attenuation of sympathetic nerve fibres remodelling, myocardial norepinephrine contents and oxidative stress.

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