Plasma Phospholipids with Long‐Chain Polyunsaturated Fatty Acids and Dihydroceramides at the Crossroads of Iron Stores and Insulin Resistance

2020 ◽  
Vol 64 (5) ◽  
pp. 1901055
Author(s):  
Jordi Mayneris‐Perxachs ◽  
Aya Mousa ◽  
Negar Naderpoor ◽  
José‐Manuel Fernández‐Real ◽  
Barbora Courten
Keyword(s):  
Insulin Resistance ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Iron Stores ◽  
Plasma Phospholipids ◽  
Long Chain

scholarly journals Plasma Phospholipids with Long‐Chain Polyunsaturated Fatty Acids and Dihydroceramides at the Crossroads of Iron Stores and Insulin Resistance

2021 ◽  
Vol 65 (18) ◽  
pp. 2170045
Author(s):  
Jordi Mayneris‐Perxachs ◽  
Aya Mousa ◽  
Negar Naderpoor ◽  
José‐Manuel Fernández‐Real ◽  
Barbora Courten
Keyword(s):  
Insulin Resistance ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Iron Stores ◽  
Plasma Phospholipids ◽  
Long Chain

scholarly journals PPAR-γ2 Pro12Ala Variant, Insulin Resistance and Plasma Long-chain Polyunsaturated Fatty Acids in Childhood Obesity

2006 ◽  
Vol 60 (4) ◽  
pp. 485-489 ◽  
Author(s):  
Silvia Scaglioni ◽  
Elvira Verduci ◽  
Michela Salvioni ◽  
Maria Luisa Biondi ◽  
Giovanni Radaelli ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Fatty Acids ◽  
Childhood Obesity ◽  
Polyunsaturated Fatty Acids ◽  
Long Chain

scholarly journals Is There a FADS2-Modulated Link between Long-Chain Polyunsaturated Fatty Acids in Plasma Phospholipids and Polyphenol Intake in Adult Subjects Who Are Overweight?

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 296
Author(s):  
Manja M. Zec ◽  
Irena Krga ◽  
Ljiljana Stojković ◽  
Maja Živković ◽  
Biljana Pokimica ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Cardiometabolic Health ◽  
Dietary Polyphenols ◽  
Plasma Phospholipids ◽  
Treatment Changes ◽  
Total Pool ◽  
Polyphenol Intake ◽  
Overweight Adults ◽  
Long Chain

Dietary polyphenols promote cardiometabolic health and are linked with long-chain polyunsaturated fatty acids in plasma phospholipids (LC-PUFA). The FADS2 polymorphisms are associated with LC-PUFA metabolism and overweight/obesity. This 4-week study examined the link between polyphenol intake, FADS2 variants (rs174593, rs174616, rs174576) and obesity in 62 overweight adults (BMI ≥ 25), allocated to consume 100 mL daily of either: Aronia juice, a rich source of polyphenols, with 1177.11 mg polyphenols (expressed as gallic acid equivalents)/100 mL (AJ, n = 22), Aronia juice with 294.28 mg polyphenols/100 mL (MJ, n = 20), or nutritionally matched polyphenol-lacking placebo as a control (PLB, n = 20). We analyzed LC-PUFA (% of total pool) by gas chromatography and FADS2 variants by real-time PCR. Four-week changes in LC-PUFA, BMI, and body weight were included in statistical models, controlling for gender and PUFA intake. Only upon AJ and MJ, the presence of FADS2 variant alleles affected changes in linoleic, arachidonic, and eicosapentaenoic acid (EPA). Upon MJ treatment, changes in EPA were inversely linked with changes in BMI (β= −0.73, p = 0.029) and weight gain (β= −2.17, p = 0.024). Only in subjects drinking AJ, the link between changes in EPA and anthropometric indices was modified by the rs174576 variant allele. Our results indicate the interaction between FADS2, fatty acid metabolism, and polyphenol intake in overweight subjects.

scholarly journals The Relationship of Insulin Resistance With SNP 276G>T at Adiponectin Gene and Plasma Long-Chain Polyunsaturated Fatty Acids in Obese Children

2009 ◽  
Vol 66 (3) ◽  
pp. 346-349 ◽  
Author(s):  
Elvira Verduci ◽  
Silvia Scaglioni ◽  
Carlo Agostoni ◽  
Giovanni Radaelli ◽  
Marialuisa Biondi ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Adiponectin Gene ◽  
Obese Children ◽  
Relationship Of ◽  
The Relationship ◽  
Long Chain

Long-chain polyunsaturated fatty acids profile in plasma phospholipids of hyperphenylalaninemic children on unrestricted diet

2011 ◽  
Vol 84 (1-2) ◽  
pp. 39-42 ◽  
Author(s):  
Marcello Giovannini ◽  
Elvira Verduci ◽  
Giovanni Radaelli ◽  
Annamaria Lammardo ◽  
Diego Minghetti ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Plasma Phospholipids ◽  
Fatty Acids Profile ◽  
Unrestricted Diet ◽  
Long Chain

Long-chain polyunsaturated fatty acids amend palmitate-induced inflammation and insulin resistance in mouse C2C12 myotubes

2016 ◽  
Vol 7 (1) ◽  
pp. 270-278 ◽  
Author(s):  
Shiuan-Chih Chen ◽  
Pei-Yin Chen ◽  
Yu-Ling Wu ◽  
Ching-Wen Chen ◽  
Haw-Wen Chen ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
C2c12 Myotubes ◽  
Long Chain

Long-chain PUFAs inhibit inflammation and insulin resistance in mouse C2C12 myotubes.

scholarly journals Dietary (n-3) Long Chain Polyunsaturated Fatty Acids Prevent Sucrose-Induced Insulin Resistance in Rats

2005 ◽  
Vol 135 (11) ◽  
pp. 2634-2638 ◽  
Author(s):  
Ghafoorunissa ◽  
Ahamed Ibrahim ◽  
Laxmi Rajkumar ◽  
Vani Acharya
Keyword(s):  
Insulin Resistance ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Long Chain
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