Targeting on Gut Microbial Metabolite Trimethylamine‐ N ‐Oxide and Short‐Chain Fatty Acid to Prevent Maternal High‐Fructose‐Diet‐Induced Developmental Programming of Hypertension in Adult Male Offspring

2019 ◽  
Vol 63 (18) ◽  
pp. 1900073 ◽  
Author(s):  
Chien‐Ning Hsu ◽  
Guo‐Ping Chang‐Chien ◽  
Sufan Lin ◽  
Chih‐Yao Hou ◽  
You‐Lin Tain
Keyword(s):  
Fatty Acid ◽  
Adult Male ◽  
Short Chain Fatty Acid ◽  
Developmental Programming ◽  
Chain Fatty Acid ◽  
Male Offspring ◽  
Short Chain ◽  
Microbial Metabolite ◽  
High Fructose Diet ◽  
High Fructose

l-Theanine affects intestinal mucosal immunity by regulating short-chain fatty acid metabolism under dietary fiber feeding

2020 ◽  
Vol 11 (9) ◽  
pp. 8369-8379
Author(s):  
Wei Xu ◽  
Ling Lin ◽  
An Liu ◽  
Tuo Zhang ◽  
Sheng Zhang ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Dietary Fiber ◽  
Fatty Acid Metabolism ◽  
Mucosal Immunity ◽  
Cholesterol Synthesis ◽  
Short Chain Fatty Acid ◽  
Acid Metabolism ◽  
Chain Fatty Acid ◽  
Short Chain

LTA regulates SCFA metabolism and improves intestinal mucosal immunity by improving cholesterol synthesis in the liver and inhibiting gluconeogenesis in the colon.

scholarly journals Influence of Supplementation of Lactoferrin, Melittin and Cecropin A to Rat Diet on Changes in Faecal Ammonia Concentrations, Short-Chain Fatty Acid Concentrations and Activities of Bacterial Enzymes

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1203
Author(s):  
Jerzy Juśkiewicz ◽  
Aleksandra Rawicka ◽  
Bartosz Fotschki ◽  
Michał Majewski ◽  
Zenon Zduńczyk
Keyword(s):  
Fatty Acid ◽  
Short Chain Fatty Acid ◽  
Control Diet ◽  
Chain Fatty Acid ◽  
Short Chain ◽  
Antimicrobial Protein ◽  
Enzyme Release ◽  
Bacterial Cells ◽  
Suppression Effect ◽  
Cecropin A

We hypothesised that the dietary addition of the bioactive antimicrobial protein lactoferrin (LF) and peptides melittin (MT) or cecropin A (CR) at a dosage of 100 mg/kg to the diet of Wistar rats would result in strong modulatory effects on faecal microbial enzymatic activity, short-chain fatty acid and ammonia concentrations. To date, the changes in bacterial extracellular and intracellular enzymatic activities upon addition of dietary AMPs have not yet been studied. This experiment lasted 15 days; during the first 5 day period, the rats were fed the control diet (S) and diets supplemented with LF, MT or CR. On days 6–15, all rats were fed the control S diet. The faecal fermentation processes were substantially stopped after two days of treatment, on average, in all rats receiving LF and two AMPs. The deepest suppression effect was observed on the last day of treatment (day 5) and persisted through days 5–8. The highest decreases in faecal bacterial β-glucosidase and β-glucuronidase activities as well as in SCFA and ammonia concentrations were observed in the rats fed the CR diet. Only in the CR animals did the mechanism of suppressed microbial fermentation involve diminished enzyme release from bacterial cells to the digesta.

Transmural trophic effect of short chain fatty acid infusions on atrophic, defunctioned rat colon

1995 ◽  
Vol 38 (9) ◽  
pp. 946-951 ◽  
Author(s):  
Peter Kissmeyer-Nielsen ◽  
Frank V. Mortensen ◽  
Søren Laurberg ◽  
Ib Hessov
Keyword(s):  
Fatty Acid ◽  
Short Chain Fatty Acid ◽  
Chain Fatty Acid ◽  
Short Chain ◽  
Rat Colon ◽  
Trophic Effect
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