Yerba Mate Stimulates Mitochondrial Biogenesis and Thermogenesis in High-Fat-Diet-Induced Obese Mice

2018 ◽  
Vol 62 (15) ◽  
pp. 1800142 ◽  
Author(s):  
Tanila Wood dos Santos ◽  
Jonatan Miranda ◽  
Lucimara Teixeira ◽  
Ana Aiastui ◽  
Ander Matheu ◽  
...  
Keyword(s):  
Mitochondrial Biogenesis ◽  
High Fat Diet ◽  
Yerba Mate ◽  
Obese Mice ◽  
High Fat

scholarly journals Antiobesity Effects of yerba maté Extract (Ilex paraguariensis ) in High-fat Diet-induced Obese Mice

Obesity ◽  
2009 ◽  
Vol 17 (12) ◽  
pp. 2127-2133 ◽  
Author(s):  
Demétrius P. Arçari ◽  
Waldemar Bartchewsky ◽  
Tanila W. dos Santos ◽  
Karim A. Oliveira ◽  
Alexandre Funck ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Ilex Paraguariensis ◽  
Yerba Mate ◽  
Obese Mice ◽  
High Fat

Cinnamomum cassiaPrevents High-Fat Diet-Induced Obesity in Mice through the Increase of Muscle Energy

2017 ◽  
Vol 45 (05) ◽  
pp. 1017-1031 ◽  
Author(s):  
Mi Young Song ◽  
Seok Yong Kang ◽  
Anna Kang ◽  
Ji Hye Hwang ◽  
Yong-Ki Park ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Mitochondrial Biogenesis ◽  
Lipid Accumulation ◽  
High Fat Diet ◽  
Muscle Cells ◽  
Skeletal Muscle Cells ◽  
Obese Mouse ◽  
Oral Glucose ◽  
Obese Mice ◽  
High Fat

The cortex of Cinnamomum cassia Presl (Cinnamomi Cortex: CC) has commonly been used for weight control in traditional medicines, but without a scientific basis. Therefore, this study was undertaken to investigate the anti-obesity effect of CC extract in a high-fat diet (HFD)-induced obese mouse model and in C2C12 mouse skeletal muscle cells. Male C57BL/6 mice were fed a normal diet or a HFD for 16 consecutive weeks, and orally administered CC extract (100 or 300[Formula: see text]mg/kg) or metformin (250[Formula: see text]mg/kg; positive control) daily for 16 weeks. CC extract administration significantly decreased body weights, food intakes, and serum levels of glucose, insulin, total cholesterol and ALT levels, prevented oral glucose tolerance and insulin resistance, inhibited the protein expressions of MyHC and PGC1[Formula: see text] and the phosphorylation of AMPK, suppressed lipid accumulation in liver, decreased adipocyte size and increased muscle mass in obese mice. For this in vitro study, C2C12 myoblasts were differentiated into the myotubes for five days, and then treated with CC extract (0.1 or 0.2[Formula: see text]mg/ml) for 24[Formula: see text]h. CC extract significantly increased ATP levels by increasing the mRNA expressions of mitochondrial biogenesis-related factors, such as, PGC1[Formula: see text], NRF-1, and Tfam, and the phosphorylations of AMPK and ACC. Our results suggest CC extract controls weight gain in obese mice by inhibiting lipid accumulation and increasing energy expenditure, and that its action mechanism involves the up-regulation of mitochondrial biogenesis in skeletal muscle cells.

Topical Application of Capsaicin Reduces Visceral Adipose Fat by Affecting Adipokine Levels in High-Fat Diet-Induced Obese Mice

Obesity ◽  
2012 ◽  
Author(s):  
Gong-Rak Lee ◽  
Mi Kyung Shin ◽  
Dong-Joon Yoon ◽  
Ah-Ram Kim ◽  
Rina Yu ◽  
...  
Keyword(s):  
Topical Application ◽  
High Fat Diet ◽  
Obese Mice ◽  
High Fat ◽  
Visceral Adipose

Proteomic analysis of the anti-obesity effect of Taeumjowui-Tang in high fat diet-induced obese mice

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
E Changkyun Park ◽  
SY Lee ◽  
SH Yun ◽  
WY Kim ◽  
Y Yi ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
High Fat Diet ◽  
Obese Mice ◽  
High Fat

Inhibition of Adipose Tissue Angiogenesis Prevents Rebound Weight Regain after Calorie Restriction Independent of Hypothalamic Melanocortin System in Obese Mice Fed a High-Fat Diet

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 287-LB
Author(s):  
HYE-JIN LEE ◽  
MUN-GYU SONG ◽  
NA-HEE HA ◽  
BO-YEONG JIN ◽  
SANG-HYUN CHOI ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Calorie Restriction ◽  
High Fat Diet ◽  
Weight Regain ◽  
Obese Mice ◽  
High Fat ◽  
Melanocortin System
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