scholarly journals Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: Relevance for anti-aging intervention

2010 ◽  
Vol 55 (3) ◽  
pp. 430-442 ◽  
Author(s):  
Cristovao F. Lima ◽  
Cristina Pereira-Wilson ◽  
Suresh I. S. Rattan
Keyword(s):  
Human Skin ◽  
Heme Oxygenase ◽  
Redox Signaling ◽  
Skin Fibroblasts ◽  
Heme Oxygenase 1 ◽  
Human Skin Fibroblasts ◽  
Normal Human Skin ◽  
Aging Intervention ◽  
Normal Human

The Effect of Practolol, In Vitro Generated Metabolites of Practolol and Chemical Analogues on the Rate of Growth of Human Skin Fibroblasts

1984 ◽  
Vol 12 (2) ◽  
pp. 89-97
Author(s):  
Graham R. Elliott ◽  
H.E. Amos ◽  
James W. Bridges
Keyword(s):  
Human Skin ◽  
Psoriasis Patient ◽  
Skin Fibroblasts ◽  
Human Skin Fibroblasts ◽  
Cell Type ◽  
Normal Human Skin ◽  
Rate Of Growth ◽  
Structural Analogues ◽  
Normal Human

The rate of growth of normal human skin fibroblasts was inhibited in a dose related, reversible, fashion by practolol (N-4-(2-hydroxy)-3 (1-methyl)-aminopropoxyphenylacetamine) (ID50 1.35 ± 0.14 x 10-3M), propranolol (1-(isopropylamino)-3(1-naphthyl-oxy)-2-propranolol) (ID50 0.145 ± 0.02 x 10-3M) and paracetamol (N-(4-hydroxyphenyl) acetamide) (ID50 0.85 ± 0.2 x 10-3M). Skin fibroblasts isolated from a psoriasis patient were more sensitive towards practolol (ID50 0.48 ± 0.14 x 10-3M) and propranolol (ID50 0.032 ± 0.002 x 10-3M), but less sensitive towards paracetamol (ID50 1.3 ± 0.07 x 10-3M). In vitro generated metabolites of practolol, using normal or Arochlor 1254-pretreated hamster liver preparations, and structural analogues of practolol had no effect upon the growth of either cell type.

The role of Nrf2 in ultraviolet A mediated heme oxygenase 1 induction in human skin fibroblasts

2010 ◽  
Vol 9 (1) ◽  
pp. 18-24 ◽  
Author(s):  
Julia L. Zhong ◽  
Gavin P. Edwards ◽  
Chintan Raval ◽  
Haibin Li ◽  
Rex M. Tyrrell
Keyword(s):  
Human Skin ◽  
Heme Oxygenase ◽  
Skin Fibroblasts ◽  
Heme Oxygenase 1 ◽  
Human Skin Fibroblasts ◽  
Ultraviolet A

scholarly journals The effect of β-carotene on the expression of interleukin-6 and heme oxygenase-1 in UV-irradiated human skin fibroblasts in vitro

FEBS Letters ◽  
2001 ◽  
Vol 509 (2) ◽  
pp. 186-190 ◽  
Author(s):  
Ute C. Obermüller-Jevic ◽  
Beate Schlegel ◽  
Andrea Flaccus ◽  
Hans Konrad Biesalski
Keyword(s):  
Human Skin ◽  
Heme Oxygenase ◽  
Interleukin 6 ◽  
Skin Fibroblasts ◽  
Heme Oxygenase 1 ◽  
Human Skin Fibroblasts ◽  
Β Carotene
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