To reverse or not to reverse? A systematic review of autograft polarity on functional outcomes following peripheral nerve repair surgery

Microsurgery ◽  
2016 ◽  
Vol 37 (2) ◽  
pp. 169-174 ◽  
Author(s):  
S. E. Roberts ◽  
S. Thibaudeau ◽  
J. C. Burrell ◽  
E. L. Zager ◽  
D. K. Cullen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Peripheral Nerve ◽  
Functional Outcomes ◽  
Nerve Repair ◽  
Peripheral Nerve Repair

The effects of sensory re-education on hand function recovery after peripheral nerve repair: A systematic review

2021 ◽  
pp. 1-12
Author(s):  
Weili Xia ◽  
Zhongfei Bai ◽  
Rongxia Dai ◽  
Jiaqi Zhang ◽  
Jiani Lu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Peripheral Nerve ◽  
Nerve Repair ◽  
Hand Function ◽  
Current Evidence ◽  
Motor Deficits ◽  
Peripheral Nerve Repair ◽  
Hand Functions ◽  
Function Recovery ◽  
Short And Long Term

BACKGROUND: Peripheral nerve injury can result in both sensory and motor deficits, and these impairments can last for a long period after nerve repair. OBJECTIVE: To systematically review the effects of sensory re-education (SR) on facilitating hand function recovery after peripheral nerve repair. METHODS: This systematic review was limited to articles published from 1970 to 20 December 2020. Electronic searching was performed in CINAHL, Embase, PubMed, Web of Science, and Medline databases to include trials investigating the effects of SR training on hand function recovery after peripheral nerve repair and included only those studies with controlled comparisons. RESULTS: Sixteen articles were included in final data synthesis. We found that only four studies could be rated as having good quality and noted obvious methodological limitations in the remaining studies. The current evidence showed that early SR with mirror visual feedback and the combinational use of classic SR and topical temporary anesthetic seemed to have long- and short-term effects, respectively on improving the sensibility and reducing the disabilities of the hand. The evidence to support the effects of conventional classical SR on improving hand functions was not strong. CONCLUSIONS: Further well-designed trials are needed to evaluate the effects of different SR techniques on hand function after nerve repair over short- and long-term periods.

scholarly journals Animal models used to study direct peripheral nerve repair: a systematic review

2020 ◽  
Vol 15 (3) ◽  
pp. 491 ◽  
Author(s):  
FranciscoJavier Vela ◽  
Guadalupe Martínez-Chacón ◽  
Alberto Ballestín ◽  
JoséLuis Campos ◽  
FranciscoMiguel Sánchez-Margallo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Animal Models ◽  
Peripheral Nerve ◽  
Nerve Repair ◽  
Peripheral Nerve Repair

Comparison of Collagen and Human Amniotic Membrane Nerve Wraps and Conduits for Peripheral Nerve Repair in Preclinical Models: A Systematic Review of the Literature

2022 ◽  
Author(s):  
Erin M. Wolfe ◽  
Sydney A. Mathis ◽  
Steven A. Ovadia ◽  
Zubin J. Panthaki
Keyword(s):  
Systematic Review ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Amniotic Membrane ◽  
Nerve Repair ◽  
Peripheral Nerve Regeneration ◽  
Human Amniotic Membrane ◽  
Preclinical Models ◽  
Peripheral Nerve Repair ◽  
Advantages And Disadvantages

Abstract Introduction Collagen and human amniotic membrane (hAM) are Food and Drug Administration (FDA)-approved biomaterials that can be used as nerve wraps or conduits for repair of peripheral nerve injuries. Both biomaterials have been shown to reduce scarring and fibrosis of injured peripheral nerves. However, comparative advantages and disadvantages have not been definitively shown in the literature. The purpose of this systematic review is to comprehensively evaluate the literature regarding the roles of hAM and collagen nerve wraps and conduits on peripheral nerve regeneration in preclinical models. Methods The MEDLINE database was queried using the PubMed search engine on July 7, 2019, with the following search strategy: (“amniotic membrane” OR “amnion”) OR (“collagen conduit” OR “nerve wrap”)] AND “nerve.” All resulting articles were screened by two independent reviewers. Nerve type, lesion type/injury model, repair type, treatment, and outcomes were assessed. Results Two hundred and fifty-eight articles were identified, and 44 studies remained after application of inclusion and exclusion criteria. Seventeen studies utilized hAM, whereas 27 studies utilized collagen wraps or conduits. Twenty-three (85%) of the collagen studies utilized conduits, and four (15%) utilized wraps. Six (35%) of the hAM studies utilized conduits and 11 (65%) utilized wraps. Two (9%) collagen studies involving a conduit and one (25%) involving a wrap demonstrated at least one significant improvement in outcomes compared with a control. While none of the hAM conduit studies showed significant improvements, eight (73%) of the studies investigating hAM wraps showed at least one significant improvement in outcomes. Conclusion The majority of studies reported positive outcomes, indicating that collagen and hAM nerve wraps and conduits both have the potential to enhance peripheral nerve regeneration. However, relatively few studies reported significant findings, except for studies evaluating hAM wraps. Preclinical models may help guide clinical practice regarding applications of these biomaterials in peripheral nerve repair.

A Systematic Review on the Use of Fibrin Glue for Peripheral Nerve Repair

2011 ◽  
Vol 127 (6) ◽  
pp. 2381-2390 ◽  
Author(s):  
Mojib Sameem ◽  
Thomas J. Wood ◽  
James R. Bain
Keyword(s):  
Systematic Review ◽  
Peripheral Nerve ◽  
Fibrin Glue ◽  
Nerve Repair ◽  
Peripheral Nerve Repair

Techniques of Peripheral Nerve Repair

1991 ◽  
Vol 2 (1) ◽  
pp. 93-104 ◽  
Author(s):  
Mark E. Harris ◽  
Suzie C. Tindall
Keyword(s):  
Peripheral Nerve ◽  
Nerve Repair ◽  
Peripheral Nerve Repair

MR imaging and T2 measurements in peripheral nerve repair with activation of Toll-like receptor 4 of neurotmesis

2014 ◽  
Vol 24 (5) ◽  
pp. 1145-1152 ◽  
Author(s):  
Xiang Zhang ◽  
Fang Zhang ◽  
Liejing Lu ◽  
Haojiang Li ◽  
Xuehua Wen ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Peripheral Nerve ◽  
Nerve Repair ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Peripheral Nerve Repair

Epineurial sheath tube (EST) technique: an experimental peripheral nerve repair model

2011 ◽  
Vol 33 (10) ◽  
pp. 1010-1015 ◽  
Author(s):  
Ahmet Bozkurt ◽  
Sebastian E Dunda ◽  
Dan O'Dey DM ◽  
Gary A Brook ◽  
Christoph V Suschek ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Nerve Repair ◽  
Peripheral Nerve Repair
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