Gracilis myocutaneous flap: Evaluation of potential risk factors and long-term donor-site morbidity

Microsurgery ◽  
2011 ◽  
Vol 31 (6) ◽  
pp. 448-453 ◽  
Author(s):  
Othon Papadopoulos ◽  
Petros Konofaos ◽  
Panos Georgiou ◽  
Chrisostomos Chrisostomidis ◽  
Zacharias Tsantoulas ◽  
...  
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Myocutaneous Flap ◽  
Donor Site ◽  
Donor Site Morbidity ◽  
Potential Risk Factors ◽  
Gracilis Myocutaneous Flap

scholarly journals Utilisation of distally based sural fasciocutaneous flaps in lower extremity reconstruction: a single-centre experience with 88 paediatric patients

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Zhaobiao Luo ◽  
Jiangdong Ni ◽  
Guohua Lv ◽  
Jianwei Wei ◽  
Lihong Liu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Donor Site ◽  
Width Ratio ◽  
Partial Necrosis ◽  
Paediatric Patients ◽  
Skin Island ◽  
Potential Risk Factors ◽  
Lower Extremity Reconstruction ◽  
Distally Based

Abstract Background No large series have analysed distally based sural fasciocutaneous (DBSF) flaps in paediatric patients. The aims of this study were to assess the reliability and analyse the potential risk factors for these flaps and to describe complications in the donor site and the functional follow-up results. Methods Between June 2002 and November 2017, 88 DBSF flaps were used to reconstruct soft tissue defects in paediatric patients. Potential risk factors, reconstruction outcomes, and complications in the donor site of the flaps were analysed. Results Among the 88 flaps, partial necrosis developed in 8 flaps (9.1%). The partial necrosis rate was significantly higher in flaps with the top edge located in the 9th zone (26.1%), with a length-width ratio (LWR) ≥ 5:1 (28.6%), and with a dimension of the skin island ≥ 100 cm2 (22.7%). Partial necrosis did not occur in flaps with a dimension of the skin island < 80.0 cm2 or with a skin-island width < 7.0 cm. The reconstruction outcomes in most paediatric patients were evaluated as “excellent” or “good”. The incidence of obvious scarring was higher in the donor site. Conclusions Partial necrosis of DBSF flaps will significantly increase when the top edge of the flap is located in the 9th zone, when the LWR of the flap is ≥ 5:1, or when the dimension of the skin island is ≥ 100.0 cm2. Flaps with a skin-island width < 7.0 cm or with a dimension of the skin island < 80 cm2 are relatively safe and reliable.

scholarly journals Assessment of Potential Risk Factors and Skin Ultrasound Presentation Associated with Breast Cancer-Related Lymphedema in Long-Term Breast Cancer Survivors

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1303
Author(s):  
Khairunnisa’ Md Yusof ◽  
Kelly A. Avery-Kiejda ◽  
Shafinah Ahmad Suhaimi ◽  
Najwa Ahmad Zamri ◽  
Muhammad Ehsan Fitri Rusli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Survivors ◽  
Potential Risk ◽  
Breast Cancer Survivors ◽  
Ultrasound Examination ◽  
Arm Circumference ◽  
Potential Risk Factors ◽  
Breast Cancer Related Lymphedema

Breast cancer has been reported to have the highest survival rate among various cancers. However, breast cancer survivors face several challenges following breast cancer treatment including breast cancer-related lymphedema (BCRL), sexual dysfunction, and psychological distress. This study aimed to investigate the potential risk factors of BCRL in long term breast cancer survivors. A total of 160 female breast cancer subjects were recruited on a voluntary basis and arm lymphedema was assessed through self-reporting of diagnosis, arm circumference measurement, and ultrasound examination. A total of 33/160 or 20.5% of the women developed BCRL with significantly higher scores for upper extremity disability (37.14 ± 18.90 vs. 20.08 ± 15.29, p < 0.001) and a lower score for quality of life (103.91 ± 21.80 vs. 115.49 ± 16.80, p = 0.009) as compared to non-lymphedema cases. Univariate analysis revealed that multiple surgeries (OR = 5.70, 95% CI: 1.21–26.8, p < 0.001), axillary lymph nodes excision (>10) (OR = 2.83, 95% CI: 0.94–8.11, p = 0.047), being overweight (≥25 kg/m2) (OR = 2.57, 95% CI: 1.04 – 6.38, p = 0.036), received fewer post-surgery rehabilitation treatment (OR = 2.37, 95% CI: 1.05–5.39, p = 0.036) and hypertension (OR = 2.38, 95% CI: 1.01–5.62, p = 0.043) were associated with an increased risk of BCRL. Meanwhile, multivariate analysis showed that multiple surgeries remained significant and elevated the likelihood of BCRL (OR = 5.83, 95% CI: 1.14–29.78, p = 0.034). Arm swelling was more prominent in the forearm area demonstrated by the highest difference of arm circumference measurement when compared to the upper arm (2.07 ± 2.48 vs. 1.34 ± 1.91 cm, p < 0.001). The total of skinfold thickness of the affected forearm was also significantly higher than the unaffected arms (p < 0.05) as evidenced by the ultrasound examination. The continuous search for risk factors in specific populations may facilitate the development of a standardized method to reduce the occurrence of BCRL and provide better management for breast cancer patients.

scholarly journals Clinical Risk Factors for Long-term Hospital Stay in Common Patients with coronavirus disease 2019(COVID-19)

2020 ◽  
Author(s):  
Wei Lu ◽  
Junjie Fang ◽  
Bin Chen ◽  
Dan Wu ◽  
Chunyao Yu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hospital Stay ◽  
Potential Risk ◽  
Clinical Laboratory ◽  
Short Term ◽  
Factors Associated ◽  
Regression Methods ◽  
Potential Risk Factors ◽  
Multivariable Regression

Abstract Background This study aimed to investigate the potential risk factors associated with hospital stay in mild patients with COVID-19. Methods A total of 109 laboratory-confirmed COVID patients with initial common subtype diseased by real-time RT-PCR that meet discharge standards were retrospectively included from January 16 to March 15 of 2020. Baseline demographic, clinical, laboratory examination was extracted from electronic medical records at the first day of admission and compared between short-term hospital stay and long-term hospital stay. Univariable and multivariable logistic regression methods were used to explore the risk factors associated with hospital stay. Results Of 109 COVID-19 patients, 61 patients were short-term stay (≤ 10 days) and 48 patients were long-term stay (> 10 days). The average age of patients in short-term stay were younger than those long-term stay(P = 0.01). Hypertension was the most common comorbidity (34%, 21/61), followed by diabetes (15%,9/61) and Cardiopathy (8%, 5/61). Fever and cough were the typical clinical manifestation in two group. Decreased WBC, Hemoglobin and increased Monocyte, MLR (Monocyte Lymphocyte ratio) and Hypersensitive CRP showed a long-term stay (all P < 0.05). The treatment of Resochin and Human immunoglobulin had a shorter hospital stay. Multivariable regression showed that MLR and CRP on admission were risk factors for predicting the hospital stay, with the HR (hazard ratio 2.03, 1.02–5.39; P = 0.022) and (1.32,1.05–3.24, P = 0.045) respectively. Conclusions The potential risk factors of MLR and CRP may help clinicians to predict the hospital stay of COVID-19 patients.

Long-term Clinical Evaluation of Tapered Multi-threaded Implants: Results and Influences of Potential Risk Factors

2006 ◽  
Vol 32 (6) ◽  
pp. 300-307 ◽  
Author(s):  
Zeev Ormianer ◽  
Ady Palti
Keyword(s):  
Risk Factors ◽  
Bone Loss ◽  
Potential Risk ◽  
Survival Rates ◽  
Marginal Bone Loss ◽  
Wide Diameter ◽  
Clinical Complications ◽  
Bone Changes ◽  
Potential Risk Factors

Abstract This prospective study evaluated the long-term performance of tapered screw implants placed in patients with a variety of potentially compromising clinical variables. Sixty patients were treated with 218 implants; each case included one or more potential risk factors associated with increased rates of implant failure, peri-implant bone loss or clinical complications in the dental literature: short implants (23%), comorbid conditions (25%), maxillary implants (61%), immediate loading (88.5%), placement into extraction sockets (91%), and partial edentulism (97%). The implants were restored with a variety of prostheses. Marginal bone changes were calculated utilizing periapical radiographs taken at placement and at all subsequent appointments utilizing a standardized paralleling device and a 1-mm measurement grid. Mean clinical follow-up was 67.5 (range: 1–94) months for implants and 60 (range: 15–74) months for prostheses. Four implants failed to integrate and were immediately replaced by wide-diameter implants. Eight prostheses sustained porcelain fracture (n = 7) or cement failure (n = 1) and were replaced. No peri-implant marginal bone loss was observed for 98% of the implants; the remaining 2% exhibited 1 mm of bone loss. Cumulative survival rates were 98.2% for implants and 96.3% for prostheses after 5 years of clinical loading. Concerns that tapered implant designs may be more prone to crestal bone loss than cylinder designs are unsupported by the results of this study. Tapered implants maintained integration and marginal bone levels despite the presence of one or more potentially compromising variables.

scholarly journals Comparison of Outcomes After Primary Laparoscopic Versus Open Approach for T1b/T2 Gallbladder Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Jiasheng Cao ◽  
Yong Wang ◽  
Bin Zhang ◽  
Jiahao Hu ◽  
Win Topatana ◽  
...  
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Tumor Size ◽  
Open Approach ◽  
Gallbladder Stone ◽  
Long Term Outcomes ◽  
Recurrence Rates ◽  
Subgroup Analyses ◽  
Potential Risk Factors

ObjectivesThe primary laparoscopic approach (PLA) for T1b/T2 gallbladder cancer (GBC) remains contradicted. We aimed to compare the perioperative and long-term outcomes after PLA versus open approach (OA) for T1b/T2 GBC.MethodsPatients with resected T1b/T2 GBC were selected from our hospital between January 2011 and August 2018. Overall survival (OS), disease-free survival (DFS), and several secondary outcomes were used to evaluate safety and effectiveness. Subgroup analyses were performed to identify significant risk factors for OS/DFS in GBC patients undergoing PLA/OA.ResultsA total of 114 patients who underwent OA (n = 61) or PLA (n = 53) were included in the study. The percent of PLA cases was increased over time from 40.0% in 2011 to 70.0% in 2018 (p &lt; 0.05). There was no significant difference in OS [hazard ratio (HR), 1.572; 95% confidence interval (CI), 0.866–2.855; p = 0.13] and DFS (HR, 1.225; 95% CI, 0.677–2.218; p = 0.49). No significance was found for intraoperative drainage placement (p = 0.253), intraoperative blood loss (p = 0.497), operation time (p = 0.105), postoperative hospitalization (p = 0.797), positive LNs (p = 0.494), total harvested LNs (p = 0.067), and recurrence rates (P = 0.334). Subgroup analyses demonstrated no significance of conversion rates after PLA (all p &gt; 0.05). Patients undergoing PLA with good/poor OS would have similar recurrence rates (p = 0.402). Positive LNs (p = 0.032) and tumor differentiation (p = 0.048) were identified as risk factors for OS after PLA, while positive LNs (p = 0.005) was identified for OS after OA. Moreover, age (p = 0.013), gallbladder stone (p = 0.008), tumor size (p = 0.028), and positive LNs (p = 0.044) were potential risk factors for DFS after OA.ConclusionsPLA for T1b/T2 GBC was comparable to OA in terms of perioperative and long-term outcomes. Less positive LNs and well-differentiated tumors were independent predictors for better OS after PLA, and less positive LNs were also identified for better OS after OA. Additionally, younger age, without gallbladder stone, smaller tumor size, and less positive LNs were potential risk factors for better DFS after OA.

scholarly journals Mood Disorders in Late-Life

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Rachel Strauss ◽  
Paul Kurdyak ◽  
Richard H Glazier
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Food Insecurity ◽  
Mood Disorder ◽  
Mood Disorders ◽  
Potential Risk ◽  
Late Life ◽  
Term Care ◽  
Potential Risk Factors

Background: Mental health concerns in late-life is a growing public health challenge as the population aged 65 and older rapidly increases locally and worldwide. An updated understanding of the causes of mood disorders in late-life and their consequences could guide interventions for this underrecognized and undertreated problem. We undertook a population-based analysis to quantify the prevalence of mood disorders in late-life in Ontario, Canada and to identify potential risk factors, and consequences. Methods: Individuals aged 65 or older participating in 4 cycles of a nationally-representative survey were included. A self-reported diagnosis of a mood disorder was used to classify individuals with mood disorders. Using linked administrative data, we quantified associations between potential risk factors, such as demographic/socioeconomic factors, substance use, and morbidity, and mood disorder. We also determined associations between mood disorders and outcomes (health service utilization and mortality) 5 years after the index interview date. Findings: The overall prevalence of mood disorders was 6.1% (4.9% among males,7.1% among females). The proportion of individuals with a mood disorder was higher among females for all potential risk factors. Statistically significant associations with mood disorder included age, sex, food insecurity, chronic opioid use, smoking, and morbidity. Individuals with mood disorders had increased odds of all long-term consequences, including hospitalization (adjusted OR [odds ratio]=1.55 95% CI [confidence interval]: 1.31-1.83); admission to long-term care (adjusted OR=2.28 95% CI: 1.71-3.02); and death (adjusted OR=1.35 95% CI: 1.13-1.63). Interpretation: Mood disorders in late-life were strongly correlated with demographic and social/behavioural factors as well as long-term health utilization outcomes. The understanding of correlations between potential risk factors for mood disorders in late-life provides a basis for potential interventions to reduce their occurrence and consequences. Interventions that target females, younger age groups, those with food insecurity or substance use, and individuals with co-morbidities may be promising.

Potential risk factors for vitamin D levels in medium- and long-term use of antiepileptic drugs in childhood

2017 ◽  
Vol 117 (2) ◽  
pp. 447-453 ◽  
Author(s):  
Edibe Pempegül Yildiz ◽  
Şükran Poyrazoglu ◽  
Gonca Bektas ◽  
Aslı Derya Kardelen ◽  
Nur Aydinli
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Antiepileptic Drugs ◽  
Potential Risk ◽  
Vitamin D Levels ◽  
Potential Risk Factors
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