scholarly journals PPARA genetic variants increase the risk for cardiac pumping function reductions following acute high‐altitude exposure: A self‐controlled study

2019 ◽  
Vol 7 (10) ◽  
Author(s):  
Jie Yang ◽  
Chuan Liu ◽  
Zhang Jihang ◽  
Jie Yu ◽  
Limeng Dai ◽  
...  
Keyword(s):  
High Altitude ◽  
Genetic Variants ◽  
Controlled Study ◽  
Altitude Exposure ◽  
Cardiac Pumping ◽  
Pumping Function

scholarly journals Changes in Subendocardial Viability Ratio With Acute High-Altitude Exposure and Protective Role of Acetazolamide

Hypertension ◽  
2013 ◽  
Vol 61 (4) ◽  
pp. 793-799 ◽  
Author(s):  
Paolo Salvi ◽  
Miriam Revera ◽  
Andrea Faini ◽  
Andrea Giuliano ◽  
Francesca Gregorini ◽  
...  
Keyword(s):  
High Altitude ◽  
Protective Role ◽  
Altitude Exposure ◽  
Subendocardial Viability Ratio

scholarly journals Mechanisms of Memory Dysfunction during High Altitude Hypoxia Training in Military Aircrew

2016 ◽  
Vol 23 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Daniel A. Nation ◽  
Mark W. Bondi ◽  
Ellis Gayles ◽  
Dean C. Delis
Keyword(s):  
High Altitude ◽  
Situational Awareness ◽  
Neuropsychological Testing ◽  
Memory Retention ◽  
Memory Encoding ◽  
Memory Dysfunction ◽  
Critical Window ◽  
Altitude Exposure ◽  
Life Saving ◽  
Mechanisms Of Memory

AbstractObjectives: Cognitive dysfunction from high altitude exposure is a major cause of civilian and military air disasters. Pilot training improves recognition of the early symptoms of altitude exposure so that countermeasures may be taken before loss of consciousness. Little is known regarding the nature of cognitive impairments manifesting within this critical window when life-saving measures may still be taken. Prior studies evaluating cognition during high altitude simulation have predominantly focused on measures of reaction time and other basic attention or motor processes. Memory encoding, retention, and retrieval represent critical cognitive functions that may be vulnerable to acute hypoxic/ischemic events and could play a major role in survival of air emergencies, yet these processes have not been studied in the context of high altitude simulation training. Methods: In a series of experiments, military aircrew underwent neuropsychological testing before, during, and after brief (15 min) exposure to high altitude simulation (20,000 ft) in a pressure-controlled chamber. Results: Acute exposure to high altitude simulation caused rapid impairment in learning and memory with relative preservation of basic visual and auditory attention. Memory dysfunction was predominantly characterized by deficiencies in memory encoding, as memory for information learned during high altitude exposure did not improve after washout at sea level. Retrieval and retention of memories learned shortly before altitude exposure were also impaired, suggesting further impairment in memory retention. Conclusions: Deficits in memory encoding and retention are rapidly induced upon exposure to high altitude, an effect that could impact life-saving situational awareness and response. (JINS, 2017, 23, 1–10)

High-Altitude Adaptation of Yak Based on Genetic Variants and Activity of Lactate Dehydrogenase-1

2010 ◽  
Vol 48 (5-6) ◽  
pp. 418-427 ◽  
Author(s):  
Liangde Kuang ◽  
Yucai Zheng ◽  
Yaqiu Lin ◽  
Yaou Xu ◽  
Suyu Jin ◽  
...  
Keyword(s):  
Lactate Dehydrogenase ◽  
High Altitude ◽  
Genetic Variants ◽  
High Altitude Adaptation ◽  
Altitude Adaptation

Cardiopulmonary Response and Body Composition Changes after Prolonged High Altitude Exposure in Women

2011 ◽  
Vol 12 (4) ◽  
pp. 357-369 ◽  
Author(s):  
Andrea Ermolao ◽  
Marco Bergamin ◽  
Alberto Carlo Rossi ◽  
Luca Dalle Carbonare ◽  
Marco Zaccaria
Keyword(s):  
Body Composition ◽  
High Altitude ◽  
Altitude Exposure ◽  
Composition Changes

Reversible Increase of Central Choroidal Thickness During High-Altitude Exposure

2015 ◽  
Vol 56 (8) ◽  
pp. 4499 ◽  
Author(s):  
M. Dominik Fischer ◽  
Andreas Schatz ◽  
Immanuel P. Seitz ◽  
Kai Schommer ◽  
Karl U. Bartz-Schmidt ◽  
...  
Keyword(s):  
High Altitude ◽  
Choroidal Thickness ◽  
Altitude Exposure
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