scholarly journals BRCA1/BRCA2 mutations in Japanese women with ductal carcinoma in situ

2019 ◽  
Vol 7 (3) ◽  
pp. e493 ◽  
Author(s):  
Yan Liu ◽  
Yoshimi Ide ◽  
Mayuko Inuzuka ◽  
Sakiko Tazawa ◽  
Yoko Kanada ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Japanese Women ◽  
Brca2 Mutations ◽  
Brca1 Brca2

scholarly journals Predictive factors for BRCA1/BRCA2 mutations in women with ductal carcinoma in situ

Cancer ◽  
2011 ◽  
Vol 118 (6) ◽  
pp. 1515-1522 ◽  
Author(s):  
Soley Bayraktar ◽  
Nisreen Elsayegh ◽  
Angelica M. Gutierrez Barrera ◽  
Heather Lin ◽  
Henry Kuerer ◽  
...  
Keyword(s):  
Predictive Factors ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Brca2 Mutations ◽  
Brca1 Brca2

Prevalence of BRCA1 and BRCA2 mutations in women diagnosed with ductal carcinoma in situ.

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. 1512-1512
Author(s):  
N. Elsayegh ◽  
S. Bayraktar ◽  
A. M. Gutierrez-Barrera ◽  
H. Lin ◽  
H. M. Kuerer ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Brca1 And Brca2 ◽  
Brca2 Mutations ◽  
Brca1 And Brca2 Mutations

The usefulness of ultrasonography in a ductal carcinoma in situ screening program for Japanese woman.

2012 ◽  
Vol 30 (27_suppl) ◽  
pp. 24-24
Author(s):  
Taijiro Kosaka
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Japanese Women ◽  
Breast Size ◽  
Tumor Diameter ◽  
Breast Cancers ◽  
Screening Programs ◽  
The U.S

24 Background: Although varying among areas, the mammogram (MMG) screening rate is very low in Japan as compared to the U.S. at approximately 20% versus nearly 80% in the U.S. On the other hand, rates of ductal carcinoma in situ (DCIS) detection among diagnosed breast cancers differ minimally: 20% in the U.S., and 15% in Japan. This is a small difference considering the difference MMG screening rates. Racial differences have been suggested to be attributable to the organization of screening programs in Japan, which also use ultrasonography (US) breast cancer screening, as well as breast size in Japanese women. Methods: We retrospectively evaluated MMG and US images of 91 DCIS cases, all 91 Japanese women who under underwent surgery between May 2010 and February 2012. US (TOSHIBA Aplio, probe 9MHz) was performed with knowledge of MMG findings. The 91 cases were divided into group with tumor detected by MMG and US (M&U), MMG detection only (M), and US detection only (U). The following parameters were analyzed: US shape (Tumor-forming lesion: TFL, Non-tumor-forming lesion: NTFL, Cystic-forming lesion: CFL), Skin-Muscle distance: SMD. We excluded asynchronous bilateral breast cancers and micro-invasive DCIS. Results: Sixty-eight lesions (73.0%) were identified by US, which revealed a NTLF in 52 cases, TLF in 9 cases and CFL in 7 cases. All cases with false-negative findings on US (Group M, n = 23) showed micro-calcifications on MMG (n=22) and with the tumor (n=1). In the U group, SMD was only 23 mm versus 43.4mm in the M group. No difference was observed in body mass index or pathological tumor diameter between the U and M. Conclusions: We found US to reveal DCIS in 73% of our cases upon reevaluation. Although US examination would not likely increase the screening detection rate for DCIS in Japanese women, US may reveal more DCIS in Japanese women, in which the breasts are comparatively small, than in western women. Further comparison of possible racial difference is warranted.

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