scholarly journals Rare variants in optic disc area gene CARD 10 enriched in primary open‐angle glaucoma

2016 ◽  
Vol 4 (6) ◽  
pp. 624-633 ◽  
Author(s):  
Tiger Zhou ◽  
Emmanuelle Souzeau ◽  
Shiwani Sharma ◽  
Owen M. Siggs ◽  
Ivan Goldberg ◽  
...  
Keyword(s):  
Optic Disc ◽  
Primary Open Angle Glaucoma ◽  
Rare Variants ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Disc Area

scholarly journals A Small Disc Area Is a Risk Factor for Visual Field Loss Progression in Primary Open-Angle Glaucoma: The Glaucoma Stereo Analysis Study

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Yasushi Kitaoka ◽  
Masaki Tanito ◽  
Yu Yokoyama ◽  
Koji Nitta ◽  
Maki Katai ◽  
...  
Keyword(s):  
Visual Field ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Visual Field Loss ◽  
Morphological Parameters ◽  
Open Angle ◽  
Analysis Study ◽  
Visual Field Progression ◽  
Stereo Analysis ◽  
Disc Area

Purpose. The Glaucoma Stereo Analysis Study, a cross-sectional multicenter collaborative study, used a stereo fundus camera (nonmyd WX) to assess various morphological parameters of the optic nerve head (ONH) in glaucoma patients. We compared the associations of each parameter between the visual field loss progression group and no-progression group. Methods. The study included 187 eyes of 187 patients with primary open-angle glaucoma or normal-tension glaucoma. We divided the mean deviation (MD) slope values of all patients into the progression group (<−0.3 dB/year) and no-progression group (≧−0.3 dB/year). ONH morphological parameters were calculated with prototype analysis software. The correlations between glaucomatous visual field progression and patient characteristics or each ONH parameter were analyzed with Spearman’s rank correlation coefficient. Results. The MD slope averages in the progression group and no-progression group were −0.58 ± 0.28 dB/year and 0.05 ± 0.26 dB/year, respectively. Among disc parameters, vertical disc width (diameter), disc area, cup area, and cup volume in the progression group were significantly less than those in the no-progression group. Logistic regression analysis revealed a significant association between the visual field progression and disc area (odds ratio 0.49/mm2 disc area). Conclusion. A smaller disc area may be associated with more rapid glaucomatous visual field progression.

scholarly journals Visual field indices and optic disc parameters in a 24-month follow-up of primary open angle glaucoma patients

1999 ◽  
Vol 77 (S229) ◽  
pp. 20-21
Author(s):  
Angelo Macrì ◽  
Maurizio Rolando ◽  
Guido Corallo ◽  
Michele Iester ◽  
Giuseppe Verrastro ◽  
...  
Keyword(s):  
Visual Field ◽  
Optic Disc ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Visual Field Indices

scholarly journals New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.

2017 ◽  
pp. ddw399 ◽  
Author(s):  
Henriët Springelkamp ◽  
Adriana I. Iglesias ◽  
Aniket Mishra ◽  
René Höhn ◽  
Robert Wojciechowski ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Disc ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Meta Analyses

scholarly journals Relationship of the 24-Hour Pattern of Intraocular Pressure with Optic Disc Appearance in Primary Open-Angle Glaucoma

Ophthalmology ◽  
2009 ◽  
Vol 116 (5) ◽  
pp. 833-839 ◽  
Author(s):  
Sunil P. Deokule ◽  
Amish Doshi ◽  
Gianmarco Vizzeri ◽  
Felipe A. Medeiros ◽  
John H.K. Liu ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Disc ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
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