scholarly journals Identification of key genes and pathways of diagnosis and prognosis in cervical cancer by bioinformatics analysis

2020 ◽  
Vol 8 (6) ◽  
Author(s):  
Hua‐ju Yang ◽  
Jin‐min Xue ◽  
Jie Li ◽  
Ling‐hong Wan ◽  
Yu‐xi Zhu
Keyword(s):  
Cervical Cancer ◽  
Bioinformatics Analysis ◽  
Diagnosis And Prognosis ◽  
Key Genes

scholarly journals Identification of candidate biomarkers correlated with the diagnosis and prognosis of cervical cancer via integrated bioinformatics analysis

2019 ◽  
Vol Volume 12 ◽  
pp. 4517-4532 ◽  
Author(s):  
Fangfang Dai ◽  
Gantao Chen ◽  
Yanqing Wang ◽  
Li Zhang ◽  
Youmei Long ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Bioinformatics Analysis ◽  
Diagnosis And Prognosis

scholarly journals Identification of Key Genes and Pathways in Cervical Cancer by Bioinformatics Analysis

2019 ◽  
Vol 16 (6) ◽  
pp. 800-812 ◽  
Author(s):  
Xuan Wu ◽  
Li Peng ◽  
Yaqin Zhang ◽  
Shilian Chen ◽  
Qian Lei ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Bioinformatics Analysis ◽  
Key Genes

scholarly journals Bioinformatics Analysis of Key Genes and Pathways of Cervical Cancer

2020 ◽  
Vol Volume 13 ◽  
pp. 13275-13283
Author(s):  
Huan Chen ◽  
Xi Wang ◽  
Huanhuan Jia ◽  
Yin Tao ◽  
Hong Zhou ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Bioinformatics Analysis ◽  
Key Genes

scholarly journals Small Non-Coding-RNA in Gynecological Malignancies

Cancers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1085
Author(s):  
Shailendra Kumar Dhar Dwivedi ◽  
Geeta Rao ◽  
Anindya Dey ◽  
Priyabrata Mukherjee ◽  
Jonathan D. Wren ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Noncoding Rna ◽  
Molecular Mechanisms ◽  
P Element ◽  
Gynecologic Malignancies ◽  
Diagnosis And Prognosis ◽  
Gynecological Malignancies ◽  
Non Coding Rna ◽  
Therapeutic Research ◽  
Regulatory Functions

Gynecologic malignancies, which include cancers of the cervix, ovary, uterus, vulva, vagina, and fallopian tube, are among the leading causes of female mortality worldwide, with the most prevalent being endometrial, ovarian, and cervical cancer. Gynecologic malignancies are complex, heterogeneous diseases, and despite extensive research efforts, the molecular mechanisms underlying their development and pathology remain largely unclear. Currently, mechanistic and therapeutic research in cancer is largely focused on protein targets that are encoded by about 1% of the human genome. Our current understanding of 99% of the genome, which includes noncoding RNA, is limited. The discovery of tens of thousands of noncoding RNAs (ncRNAs), possessing either structural or regulatory functions, has fundamentally altered our understanding of genetics, physiology, pathophysiology, and disease treatment as they relate to gynecologic malignancies. In recent years, it has become clear that ncRNAs are relatively stable, and can serve as biomarkers for cancer diagnosis and prognosis, as well as guide therapy choices. Here we discuss the role of small non-coding RNAs, i.e., microRNAs (miRs), P-Element induced wimpy testis interacting (PIWI) RNAs (piRNAs), and tRNA-derived small RNAs in gynecological malignancies, specifically focusing on ovarian, endometrial, and cervical cancer.

Identification of diagnosis and prognosis gene markers in B-ALL with ETV6-RUNX1 fusion by Integrated Bioinformatics Analysis

Gene ◽  
2022 ◽  
pp. 146132
Author(s):  
Hongkai Zhu ◽  
Rong Zhang ◽  
Ruijuan Li ◽  
Zhihua Wang ◽  
Heng Li ◽  
...  
Keyword(s):  
Bioinformatics Analysis ◽  
Gene Markers ◽  
Diagnosis And Prognosis
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