scholarly journals Epigenetic modifications in pancreas development, diabetes, and therapeutics

2022 ◽  
Author(s):  
Suneesh Kaimala ◽  
Challagandla Anil Kumar ◽  
Mohammed Z. Allouh ◽  
Suraiya Anjum Ansari ◽  
Bright Starling Emerald
Keyword(s):  
Epigenetic Modifications ◽  
Pancreas Development

Identification of MicroRNAs Regulating Ptf1a Expression in Mouse Pancreas Development*

2010 ◽  
Vol 2009 (12) ◽  
pp. 1607-1612
Author(s):  
Yang AN ◽  
Yan-Kun YANG ◽  
Fei GAO ◽  
Kuan-Yu ZHU ◽  
Tan-Wei MU ◽  
...  
Keyword(s):  
Pancreas Development ◽  
Mouse Pancreas

Epigenetic Modifications as Therapeutic Targets

2020 ◽  
Vol 21 (11) ◽  
pp. 1046-1046
Author(s):  
Yi-Chao Zheng ◽  
Si-Qi Feng
Keyword(s):  
Therapeutic Targets ◽  
Epigenetic Modifications

Epigenetic Studies in Psychotherapy: A Systematic Review

2020 ◽  
Vol 16 (2) ◽  
pp. 86-92
Author(s):  
Rafael Penadés ◽  
Bárbara Arias ◽  
Mar Fatjó-Vilas ◽  
Laura González-Vallespí ◽  
Clemente García-Rizo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dna Methylation ◽  
Mental Disorders ◽  
Epigenetic Modifications ◽  
Symptom Improvement ◽  
Epigenetic Changes ◽  
Main Hypothesis ◽  
Psychological Treatments ◽  
Time Period ◽  
The Impact

Background: Epigenetic modifications appear to be dynamic and they might be affected by environmental factors. The possibility of influencing these processes through psychotherapy has been suggested. Objective: To analyse the impact of psychotherapy on epigenetics when applied to mental disorders. The main hypothesis is that psychological treatments will produce epigenetic modifications related to the improvement of treated symptoms. Methods: A computerised and systematic search was completed throughout the time period from 1990 to 2019 on the PubMed, ScienceDirect and Scopus databases. Results: In total, 11 studies were selected. The studies were evaluated for the theoretical framework, genes involved, type of psychotherapy and clinical challenges and perspectives. All studies showed detectable changes at the epigenetic level, like DNA methylation changes, associated with symptom improvement after psychotherapy. Conclusion: Methylation profiles could be moderating treatment effects of psychotherapy. Beyond the detected epigenetic changes after psychotherapy, the epigenetic status before the implementation could act as an effective predictor of response.

Sign in / Sign up

Export Citation Format

Share Document