Sustained effect of high-dose intrathecal baclofen in primary generalized dystonia: A 2-year follow-up study

1997 ◽  
Vol 12 (6) ◽  
pp. 1100-1102 ◽  
Author(s):  
N. J. Diederich ◽  
C. L. Comella ◽  
G. Matge ◽  
G. Becker ◽  
F. Schiltz ◽  
...  
2017 ◽  
Vol 15 (2) ◽  
pp. 173-182 ◽  
Author(s):  
Afsane Bahrami ◽  
Seyed Reza Mazloum ◽  
Shahrokh Maghsoudi ◽  
Davood Soleimani ◽  
Sayyed Saeid Khayyatzadeh ◽  
...  

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Takeshi Satow ◽  
Masafumi Ogawa ◽  
Taro Komuro

BACKGROUNDLesch-Nyhan disease (LND) is a very rare metabolic disorder involving the purine salvage pathway. LND manifests hyperuricemia, self-mutilation, cognitive impairment, and movement disorders such as spasticity and dystonia, whose control is difficult pharmaceutically.OBSERVATIONSIntrathecal baclofen (ITB) therapy was received by a 22-year-old male for generalized dystonia. His paroxysmal abnormal dystonic posturing reduced after surgery, making the task of caregivers easier despite the unchanged assignment on the dystonia scale during a follow-up period of 4 years.LESSONSITB may be a safe and feasible option for dystonic symptoms and difficulty with nursing care in patients with LND.


2014 ◽  
Vol 95 (6) ◽  
pp. 1032-1038 ◽  
Author(s):  
Léo Borrini ◽  
Djamel Bensmail ◽  
Jean-Baptiste Thiebaut ◽  
Caroline Hugeron ◽  
Célia Rech ◽  
...  

2015 ◽  
Vol 25 (9) ◽  
pp. 1633-1638 ◽  
Author(s):  
Enrique Lanzarini ◽  
Xavier Nogués ◽  
Albert Goday ◽  
David Benaiges ◽  
Marta de Ramón ◽  
...  

2009 ◽  
Vol 90 (2) ◽  
pp. 105-110 ◽  
Author(s):  
S. T. F. M. Frequin ◽  
K. J. B. Lamers ◽  
F. Barkhof ◽  
G. F. Borm ◽  
O. R. Hommes

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