scholarly journals Visual Impairment Is More Common in Parkinson’s Disease and Is a Risk Factor for Poor Health Outcomes

2020 ◽  
Vol 35 (9) ◽  
pp. 1542-1549 ◽  
Author(s):  
Ali G. Hamedani ◽  
Danielle S. Abraham ◽  
Maureen G. Maguire ◽  
Allison W. Willis
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Risk Factor ◽  
Health Outcomes ◽  
Visual Impairment ◽  
Poor Health

Variation in the miRNA-433 binding site of FGF20 is a risk factor for Parkinson's disease in Iranian population

2015 ◽  
Vol 355 (1-2) ◽  
pp. 72-74 ◽  
Author(s):  
Leyla Haghnejad ◽  
Babak Emamalizadeh ◽  
Javad Jamshidi ◽  
Alireza Zare Bidoki ◽  
Hamid Ghaedi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Risk Factor ◽  
Binding Site ◽  
Iranian Population

Apolipoprotein E genotype as a risk factor for susceptibility to and dementia in Parkinson’s Disease

2009 ◽  
Vol 256 (3) ◽  
pp. 493-498 ◽  
Author(s):  
C. H. Williams-Gray ◽  
A. Goris ◽  
M. Saiki ◽  
T. Foltynie ◽  
D. A. S. Compston ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Risk Factor ◽  
Apolipoprotein E ◽  
Apolipoprotein E Genotype

scholarly journals Genetic Analysis of LRRK2 R1628P in Parkinson’s Disease in Asian Populations

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Yuan Zhang ◽  
Qiying Sun ◽  
Minhan Yi ◽  
Xun Zhou ◽  
Jifeng Guo ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Risk Factor ◽  
Chinese Population ◽  
Genetic Factors ◽  
Meta Analysis ◽  
Asian Population ◽  
High Quality ◽  
Asian Populations ◽  
Risk Variants

Although the etiology of Parkinson’s disease (PD) remains unclear, there is increasing evidence of genetic factors contributing to the onset of PD. Various mutations and risk variants of the gene LRRK2 have been reported, but the association between LRRK2 R1628P and PD is still inconsistent. Thus, we conducted a meta-analysis to determine the potential relationship between R1628P and PD. Our study sample was an aggregate of 17 publications, which in total consisted of 9,275 PD patients and 8,114 controls. All of these articles are of high quality according to NOS, and there was no obvious reporting bias or heterogeneity. In a general Asian population, the pooled OR of the risk genotype contrasts was 1.83 (95% CI: 1.57, 2.13). When stratified by ethnicity, the pooled ORs were 1.84 (95% CI: 1.56, 2.18) in a Chinese population and 1.79 (95% CI: 1.27, 2.52) in a non-Chinese population. Our study suggests that LRRK2 R1628P appears to be a risk factor for PD in Asian populations, both Chinese and non-Chinese.

scholarly journals Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease

2019 ◽  
Vol 12 (6) ◽  
pp. 609-616
Author(s):  
Sacha Bohler ◽  
Xiaosong Liu ◽  
Julian Krauskopf ◽  
Florian Caiment ◽  
Jiri Aubrecht ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Risk Factor ◽  
Potential Risk ◽  
Potential Risk Factor ◽  
Acetaminophen Overdose
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