Dopamine Metabolism May Have Unexpected Benefits for Mitochondrial Energy Production

2020 ◽  
Vol 35 (4) ◽  
pp. 562-562
Author(s):  
Laurie H. Sanders ◽  
Nicole Calakos
Keyword(s):  
Energy Production ◽  
Dopamine Metabolism ◽  
Mitochondrial Energy Production

scholarly journals Lower Mitochondrial Energy Production of the Thigh Muscles in Patients With Low‐Normal Ankle‐Brachial Index

2017 ◽  
Vol 6 (9) ◽  
Author(s):  
Majd AlGhatrif ◽  
Ariel Zane ◽  
Matt Oberdier ◽  
Marco Canepa ◽  
Stephanie Studenski ◽  
...  
Keyword(s):  
Energy Production ◽  
Ankle Brachial Index ◽  
Thigh Muscles ◽  
Mitochondrial Energy Production

Effect of mangiferin on mitochondrial energy production in experimentally induced myocardial infarcted rats

2006 ◽  
Vol 44 (6) ◽  
pp. 519-525 ◽  
Author(s):  
S. Prabhu ◽  
Mallika Jainu ◽  
K.E. Sabitha ◽  
C.S. Shyamala Devi
Keyword(s):  
Energy Production ◽  
Mitochondrial Energy Production ◽  
Experimentally Induced

scholarly journals Methylpiperidinopyrazole Attenuates Estrogen-Induced Mitochondrial Energy Production and Subsequent Osteoblast Maturation via an Estrogen Receptor Alpha-Dependent Mechanism

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2876
Author(s):  
Poh-Shiow Yeh ◽  
Jui-Tai Chen ◽  
Yih-Giun Cherng ◽  
Shun-Tai Yang ◽  
Yu-Ting Tai ◽  
...  
Keyword(s):  
Energy Production ◽  
Estrogen Receptor Alpha ◽  
Type I Collagen ◽  
Atp Synthesis ◽  
Neonatal Rat ◽  
Type I ◽  
Collagen Mrna ◽  
Adenosine Phosphate ◽  
Mitochondrial Energy Production ◽  
Osteoblast Maturation

An estrogen deficiency is the main cause of osteoporosis in postmenopausal women. In bone remodeling, estrogen receptors (ERs) can mediate estrogen-transducing signals. Methylpiperidinopyrazole (MPP) is a highly specific antagonist of ER-alpha (ERα). This study was designed to evaluate the effects of MPP on estrogen-induced energy production, subsequent osteoblast maturation, and the possible mechanisms. Exposure of primary osteoblasts isolated from neonatal rat calvarias to MPP did not affect cell morphology or survival. Estradiol can induce translocation of ERα into mitochondria from the cytoplasm. Interestingly, pretreatment of rat calvarial osteoblasts with MPP lowered estrogen-induced ERα translocation. Sequentially, estrogen-triggered expressions of mitochondrial energy production-linked cytochrome c oxidase (COX) I and COX II messenger (m)RNAs were inhibited following pretreatment with MPP. Consequently, MPP caused decreases in estrogen-triggered augmentation of the activities of mitochondrial respiratory complex enzymes and levels of cellular adenosine phosphate (ATP). During progression of osteoblast maturation, estrogen induced bone morphogenetic protein (BMP)-6 and type I collagen mRNA expressions, but MPP treatment inhibited such induction. Consequently, estrogen-induced osteoblast activation and mineralization were attenuated after exposure to MPP. Taken together, MPP suppressed estrogen-induced osteoblast maturation through decreasing chromosomal osteogenesis-related BMP-6 and type I collagen mRNA expressions and mitochondrial ATP synthesis due to inhibiting energy production-linked COX I and II mRNA expressions. MPP can appropriately be applied to evaluate estrogen-involved bioenergetics and osteoblast maturation.

Hormonal regulation of mitochondrial energy production

2005 ◽  
Vol 8 (4) ◽  
pp. 415-418 ◽  
Author(s):  
Patrick Ritz ◽  
Jean-François Dumas ◽  
Pierre-Henri Ducluzeau ◽  
Gilles Simard
Keyword(s):  
Hormonal Regulation ◽  
Energy Production ◽  
Mitochondrial Energy Production

Cdk1 boosts mitochondrial energy production

2014 ◽  
Vol 16 (6) ◽  
pp. 511-511 ◽  
Author(s):  
Christina Karlsson Rosenthal
Keyword(s):  
Energy Production ◽  
Mitochondrial Energy Production

scholarly journals Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress

PLoS Biology ◽  
2015 ◽  
Vol 13 (7) ◽  
pp. e1002197 ◽  
Author(s):  
Manish Jaiswal ◽  
Nele A. Haelterman ◽  
Hector Sandoval ◽  
Bo Xiong ◽  
Taraka Donti ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Energy Production ◽  
Photoreceptor Degeneration ◽  
Mitochondrial Energy Production

scholarly journals p53-Dependent Regulation of Mitochondrial Energy Production by the RelA Subunit of NF-κB

2011 ◽  
Vol 71 (16) ◽  
pp. 5588-5597 ◽  
Author(s):  
Renée F. Johnson ◽  
Ini-Isabée Witzel ◽  
Neil D. Perkins
Keyword(s):  
Energy Production ◽  
Mitochondrial Energy Production
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